HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 13 matching records:

Displaying record number 56357

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HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location p17(84-92)
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Epitope Name TI9
Subtype B
Species (MHC/HLA) human(A*11)
Immunogen HIV-1 infection
Country Australia, Canada, Germany, United States
Experimental methods  
Keywords escape, HLA associated polymorphism

Notes

References

Brumme2008 Zabrina L. Brumme, Chanson J. Brumme, Jonathan Carlson, Hendrik Streeck, Mina John, Quentin Eichbaum, Brian L Block, Brett Baker, Carl Kadie, Martin Markowitz, Heiko Jessen, Anthony D. Kelleher, Eric Rosenberg, John Kaldor, Yuko Yuki, Mary Carrington, Todd M. Allen, Simon Mallal, Marcus Altfeld, David Heckerman, and Bruce D. Walker. Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection. J. Virol., 82(18):9216-9227, Sep 2008. PubMed ID: 18614631. Show all entries for this paper.


Displaying record number 57303

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HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location p17(84-92)
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Epitope Name TI9
Subtype B
Species (MHC/HLA) (A*11)
Immunogen peptide-HLA interaction
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Other
Keywords epitope processing

Notes

References

Tenzer2009 Stefan Tenzer, Edmund Wee, Anne Burgevin, Guillaume Stewart-Jones, Lone Friis, Kasper Lamberth, Chih-hao Chang, Mikkel Harndahl, Mirjana Weimershaus, Jan Gerstoft, Nadja Akkad, Paul Klenerman, Lars Fugger, E. Yvonne Jones, Andrew J. McMichael, Søren Buus, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. Antigen Processing Influences HIV-Specific Cytotoxic T Lymphocyte Immunodominance. Nat. Immunol., 10(6):636-646, Jun 2009. PubMed ID: 19412183. Show all entries for this paper.


Displaying record number 61636

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HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location p17
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Epitope Name A11-TI9
Subtype B
Species (MHC/HLA) human(A*11)
Immunogen HIV-1 infection
Country Canada
Experimental methods Chromium-release assay, Other
Keywords epitope processing, escape

Notes

References

Zhang2012 Shao Chong Zhang, Eric Martin, Mariko Shimada, Sasha Blue Godfrey, Jennifer Fricke, Shirley Locastro, Nicole Y. Lai, Paul Liebesny, Jonathan M. Carlson, Chanson J. Brumme, Oluwatobi Awele Ogbechie, Huabiao Chen, Bruce D. Walker, Zabrina L. Brumme, Daniel G. Kavanagh, and Sylvie Le Gall. Aminopeptidase Substrate Preference Affects HIV Epitope Presentation and Predicts Immune Escape Patterns in HIV-Infected Individuals. J. Immunol., 188(12):5924-5934, 15 Jun 2012. PubMed ID: 22586036. Show all entries for this paper.


Displaying record number 1539

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HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location p17(84-92 SF2)
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.


Displaying record number 1659

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HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location p17(84-92)
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Species (MHC/HLA) human(A11)
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


Displaying record number 55715

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HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location Gag
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Epitope Name TI9-A11
Subtype B, F
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Country Argentina
Experimental methods  
Keywords dynamics, HLA associated polymorphism

Notes

References

Dilernia2008 Dario Alberto Dilernia, Leandro Jones, Sabrina Rodriguez, Gabriela Turk, Andrea E Rubio, Sandra Pampuro, Manuel Gomez-Carrillo, Christian Bautista, Gabriel Deluchi, Jorge Benetucci, María Beatriz Lasala, Leonardo Lourtau, Marcelo Horacio Losso, Héctor Perez, Pedro Cahn, and Horacio Salomón. HLA-Driven Convergence of HIV-1 Viral Subtypes B and F Toward the Adaptation to Immune Responses in Human Populations. PLoS ONE, 3(10):e3429, 2008. PubMed ID: 18941505. Show all entries for this paper.


Displaying record number 108

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HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location p17(84-92)
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Experimental methods  
Keywords responses in children, mother-to-infant transmission

Notes

References

Brander1995a Christian Brander and Bruce Walker. The HLA-Class I Restricted CTL Response in HIV-1 Infection: Identification of Optimal Epitopes. In The HLA-Class I Restricted CTL Response in HIV-1 Infection: Identification of Optimal Epitopes. pages IV--1--IV--9. Los Alamos National Laboratory, Theoretical Biology and Biophysics, Los Alamos, New Mexico, 1995. URL: http://hiv-web.lanl.gov/immunology. Show all entries for this paper.


Displaying record number 55917

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HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location p17
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Epitope Name TI9(p17)
Subtype B
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 109

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HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location p17(84-92)
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Birk1998 M. Birk, A. Vahlne, A. Sonnerborg, and M. Sallberg. Nonsynonymous Mutations within the Human Immunodeficiency Virus Type 1 p17 Gene Are Clustered to Sequences Binding to the Host Human Leukocyte Antigen Class I Molecules. AIDS Res. Hum. Retroviruses, 14:241-248, 1998. PubMed ID: 9491914. Show all entries for this paper.


Displaying record number 1445

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HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location p17(84-92)
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Ferrari2000 G. Ferrari, D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. AIDS Res. Hum. Retroviruses, 16(14):1433-43, 20 Sep 2000. PubMed ID: 11018863. Show all entries for this paper.


Displaying record number 60307

Download this epitope record as JSON.

HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location Gag(84-92)
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Epitope Name TI9
Species (MHC/HLA) human(A*32)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60308

Download this epitope record as JSON.

HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location Gag(84-92)
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Epitope Name TI9
Species (MHC/HLA) human(B*13)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60309

Download this epitope record as JSON.

HXB2 Location Gag(84-92)
p17(84-92)
DNA(1039..1065)
Gag Epitope Map
Author Location Gag(84-92)
Epitope TLYCVHQRI Epitope Alignment
TLYCVHQRI epitope logo
Epitope Name TI9
Species (MHC/HLA) human(C*12)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


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