HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 60306

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HXB2 Location Gag(84-91)
p17(84-91)
DNA(1039..1062)
Gag Epitope Map
Author Location Gag(84-91)
Epitope TLYCVHQK Epitope Alignment
TLYCVHQK epitope logo
Epitope Name TK8
Species (MHC/HLA) human(A*11)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 110

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HXB2 Location Gag(84-91)
p17(84-91)
DNA(1039..1062)
Gag Epitope Map
Author Location p17(84-91)
Epitope TLYCVHQK Epitope Alignment
TLYCVHQK epitope logo
Species (MHC/HLA) human(A*11:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope, A-list

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 62780

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HXB2 Location Gag(84-91)
p17(84-91)
DNA(1039..1062)
Gag Epitope Map
Author Location p17(84-91)
Epitope TLYCVHQK Epitope Alignment
TLYCVHQK epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen engineered
Experimental methods Other, Relative replication capacity assay
Keywords assay or method development, protective allele

Notes

References

Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.


Displaying record number 62889

Download this epitope record as JSON.

HXB2 Location Gag(84-91)
p17(84-91)
Gag Epitope Map
Author Location Gag
Epitope TLYCVHQK Epitope Alignment
TLYCVHQK epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection, vaccine
Experimental methods Other
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type polyepitope, adenovirus type 5 (Ad5)
Vaccine component Gag, Nef, Pol

Notes

References

Boppana2020 Sushma Boppana, Andrew Fiore-Gartland, Anju Bansal, and Paul Goepfert. Cross-Reactive CD8 T-Cell Responses Elicited by Adenovirus Type 5-Based HIV-1 Vaccines Contributed to Early Viral Evolution in Vaccine Recipients Who Became Infected. J Virol, 94(2):JVI01632-19 doi, Jan 2020. PubMed ID: 31645444 Show all entries for this paper.


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