HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 60647

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HXB2 Location Gag(242-250)
p24(110-118)
DNA(1513..1539)
Gag Epitope Map
Author Location p24(110-118)
Epitope TLQEQIGWM Epitope Alignment
TLQEQIGWM epitope logo
Epitope Name TM-9
Subtype B, C
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 52689

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HXB2 Location Gag(242-250)
p24(110-118)
DNA(1513..1539)
Gag Epitope Map
Author Location Gag(242-)
Epitope TLQEQIGWM Epitope Alignment
TLQEQIGWM epitope logo
Epitope Name Gag242
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection, vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay
Keywords binding affinity, subtype comparisons, computational epitope prediction

Vaccine Details

Vaccine type peptide
Vaccine component p24 Gag
Adjuvant Incomplete Freund's Adjuvant (IFA)

Notes

References

Corbet2003 Sylvie Corbet, Henrik Vedel Nielsen, Lasse Vinner, Sanne Lauemoller, Dominic Therrien, Sheila Tang, Gitte Kronborg, Lars Mathiesen, Paul Chaplin, Søren Brunak, Søren Buus, and Anders Fomsgaard. Optimization and Immune Recognition of Multiple Novel Conserved HLA-A2, Human Immunodeficiency Virus Type 1-Specific CTL Epitopes. J. Gen. Virol., 84(Pt 9):2409-2421, Sep 2003. PubMed ID: 12917462. Show all entries for this paper.


Displaying record number 55368

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HXB2 Location Gag(242-250)
p24(110-118)
DNA(1513..1539)
Gag Epitope Map
Author Location  
Epitope TLQEQIGWM Epitope Alignment
TLQEQIGWM epitope logo
Show epitope variants
Epitope Name Gag 242
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country Denmark
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords  

Notes

References

Thorn2007 Mette Thorn, Sheila Tang, Dominic Therrien, Henrik Kløverpris, Lasse Vinner, Gitte Kronborg, Jan Gerstoft, Sylvie Corbet, and Anders Fomsgaard. Sequence Conservation of Subdominant HLA-A2-Binding CTL Epitopes in HIV-1 Clinical Isolates and CD8+ T-Lymphocyte Cross-Recognition May Explain the Immune Reaction in Infected Individuals. APMIS, 115(6):757-768, Jun 2007. PubMed ID: 17550385. Show all entries for this paper.


Displaying record number 56057

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HXB2 Location Gag(242-250)
p24(110-118)
DNA(1513..1539)
Gag Epitope Map
Author Location Gag(242-)
Epitope TLQEQIGWM Epitope Alignment
TLQEQIGWM epitope logo
Show epitope variants
Epitope Name Gag242
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country Denmark
Experimental methods Flow cytometric T-cell cytokine assay
Keywords rate of progression, escape, acute/early infection

Notes

References

Fomsgaard2008 Anders Fomsgaard, Lasse Vinner, Dominic Therrien, Louise B. Jørgensen, Claus Nielsen, Lars Mathiesen, Court Pedersen, and Sylvie Corbet. Full-Length Characterization of A1/D Intersubtype Recombinant Genomes from a Therapy-Induced HIV Type 1 Controller during Acute Infection and His Noncontrolling Partner. AIDS Res. Hum. Retroviruses, 24(3):463-472, Mar 2008. PubMed ID: 18373434. Show all entries for this paper.


Displaying record number 57023

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HXB2 Location Gag(242-250)
p24(110-118)
DNA(1513..1539)
Gag Epitope Map
Author Location Gag
Epitope TLQEQIGWM Epitope Alignment
TLQEQIGWM epitope logo
Subtype CRF01_AE
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


Displaying record number 58468

Download this epitope record as JSON.

HXB2 Location Gag(242-250)
p24(110-118)
DNA(1513..1539)
Gag Epitope Map
Author Location p24(110-118)
Epitope TLQEQIGWM Epitope Alignment
TLQEQIGWM epitope logo
Subtype A1
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Proliferation
Keywords assay or method development, characterizing CD8+ T cells

Notes

References

Richmond2011 Meika Richmond, Lyle R. McKinnon, Sandra A. Koesters Kiazyk, Charles Wachihi, Makobu Kimani, Joshua Kimani, Francis A. Plummer, and T. Blake Ball. Epitope Mapping of HIV-Specific CD8+ T Cell Responses by Multiple Immunological Readouts Reveals Distinct Specificities Defined by Function. J. Virol., 85(3):1275-1286, Feb 2011. PubMed ID: 21084478. Show all entries for this paper.


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