HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 7 matching records:

Displaying record number 60603

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HXB2 Location Gag(151-159)
p24(19-27)
DNA(1240..1266)
Gag Epitope Map
Author Location p24(19-27)
Epitope TLNAWVKVI Epitope Alignment
TLNAWVKVI epitope logo
Epitope Name TI-9
Subtype B, C
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 54313

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HXB2 Location Gag(151-159)
p24(19-27)
DNA(1240..1266)
Gag Epitope Map
Author Location p24(19-27)
Epitope TLNAWVKVI Epitope Alignment
TLNAWVKVI epitope logo
Species (MHC/HLA) human(A*02:01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Cytokine production, HLA binding, Other
Keywords vaccine-induced immune responses, HLA cross-presentation, HLA associated polymorphism

Notes

References

Reche2006 Pedro A. Reche, Derin B. Keskin, Rebecca E. Hussey, Petronela Ancuta, Dana Gabuzda, and Ellis L. Reinherz. Elicitation from Virus-Naive Individuals of Cytotoxic T Lymphocytes Directed against Conserved HIV-1 Epitopes. Med. Immunol., 5:1, 2006. PubMed ID: 16674822. Show all entries for this paper.


Displaying record number 55360

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HXB2 Location Gag(151-159)
p24(19-27)
DNA(1240..1266)
Gag Epitope Map
Author Location p24(19-27)
Epitope TLNAWVKVI Epitope Alignment
TLNAWVKVI epitope logo
Epitope Name 9I
Species (MHC/HLA) human(A*02:01)
Immunogen in vitro stimulation or selection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, HLA binding
Keywords binding affinity, immunodominance, dendritic cells

Notes

References

Schaubert2007 Keri L. Schaubert, David A. Price, Nicole Frahm, Jinzhu Li, Hwee L. Ng, Aviva Joseph, Elyse Paul, Biswanath Majumder, Velpandi Ayyavoo, Emma Gostick, Sharon Adams, Francesco M. Marincola, Andrew K. Sewell, Marcus Altfeld, Jason M. Brenchley, Daniel C. Douek, Otto O. Yang, Christian Brander, Harris Goldstein, and June Kan-Mitchell. Availability of a Diversely Avid CD8+ T Cell Repertoire Specific for the Subdominant HLA-A2-Restricted HIV-1 Gag p24(19-27) Epitope. J. Immunol., 178(12):7756-7766, 15 Jun 2007. PubMed ID: 17548613. Show all entries for this paper.


Displaying record number 57070

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HXB2 Location Gag(151-159)
p24(19-27)
DNA(1240..1266)
Gag Epitope Map
Author Location p24(19-27 DU422)
Epitope TLNAWVKVI Epitope Alignment
TLNAWVKVI epitope logo
Subtype B
Species (MHC/HLA) human(A*02:01)
Immunogen in vitro stimulation or selection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Tetramer binding
Keywords dendritic cells

Notes

References

Colleton2009 Bonnie A. Colleton, Xiao-Li Huang, Nada M. Melhem, Zheng Fan, Luann Borowski, Giovanna Rappocciolo, and Charles R. Rinaldo. Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells. J. Virol., 83(12):6288-6299, Jun 2009. PubMed ID: 19357176. Show all entries for this paper.


Displaying record number 55749

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HXB2 Location Gag(151-159)
p24(19-27)
DNA(1240..1266)
Gag Epitope Map
Author Location Gag
Epitope TLNAWVKVI Epitope Alignment
TLNAWVKVI epitope logo
Subtype A, C, D
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords subtype comparisons

Notes

References

Gudmundsdotter2008 L. Gudmundsdotter, D. Bernasconi, B. Hejdeman, E. Sandstrom, A. Alaeus, K. Lidman, B. Ensoli, B. Wahren, and S. Buttò. Cross-Clade Immune Responses to Gag p24 in Patients Infected with Different HIV-1 Subtypes and Correlation with HLA Class I and II Alleles. Vaccine, 26(40):5182-5187, 19 Sep 2008. PubMed ID: 18479789. Show all entries for this paper.


Displaying record number 53623

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HXB2 Location Gag(151-159)
p24(19-27)
DNA(1240..1266)
Gag Epitope Map
Author Location p24(19-27 HXB2)
Epitope TLNAWVKVI Epitope Alignment
TLNAWVKVI epitope logo
Epitope Name 24D
Subtype B
Species (MHC/HLA) transgenic mouse(A2)
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Cytokine production
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine strain multiple epitope immunogen
Vaccine component p17/p24 Gag, Pol
Adjuvant IL-12

Notes

References

Bolesta2005a Elizabeth Bolesta, Jaroslaw Gzyl, Andrzej Wierzbicki, Dariusz Kmieciak, Aleksandra Kowalczyk, Yutaro Kaneko, Alagarsamy Srinivasan, and Danuta Kozbor. Clustered Epitopes within the Gag-Pol Fusion Protein DNA Vaccine Enhance Immune Responses and Protection against Challenge with Recombinant Vaccinia Viruses Expressing HIV-1 Gag and Pol Antigens. Virology, 332(2):467-479, 20 Feb 2005. PubMed ID: 15680412. Show all entries for this paper.


Displaying record number 1650

Download this epitope record as JSON.

HXB2 Location Gag(151-159)
p24(19-27)
DNA(1240..1266)
Gag Epitope Map
Author Location p24(150-159)
Epitope TLNAWVKVI Epitope Alignment
TLNAWVKVI epitope logo
Species (MHC/HLA) human(A2)
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords subtype comparisons, HIV exposed persistently seronegative (HEPS)

Notes

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


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