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HIV Molecular Immunology Database

Search CTL/CD8+ T-Cell Epitope Database

Found 10 matching records:

Displaying record number 60304

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HXB2 Location Pol(781-789)
Integrase(66-74)
DNA(4425..4451)
Pol Epitope Map
Author Location Pol(781-789)
Epitope THLEGKIIL Epitope Alignment
THLEGKIIL epitope logo
Epitope Name TL9
Species (MHC/HLA) human(A*31)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 56003

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HXB2 Location Pol(781-789)
Integrase(66-74)
DNA(4425..4451)
Pol Epitope Map
Author Location Integrase
Epitope THLEGKIIL Epitope Alignment
THLEGKIIL epitope logo
Epitope Name TL9(Integrase)
Subtype B
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 54097

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HXB2 Location Pol(781-789)
Integrase(66-74)
DNA(4425..4451)
Pol Epitope Map
Author Location  
Epitope THLEGKIIL Epitope Alignment
THLEGKIIL epitope logo
Epitope Name TIL9
Species (MHC/HLA) human(B*15:10)
Immunogen  
Experimental methods  
Keywords optimal epitope, A-list

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 53940

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HXB2 Location Pol(781-789)
Integrase(66-74)
DNA(4425..4451)
Pol Epitope Map
Author Location ( C consensus)
Epitope THLEGKIIL Epitope Alignment
THLEGKIIL epitope logo
Subtype C
Species (MHC/HLA) human(B*15:10)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope, HLA associated polymorphism

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 60305

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HXB2 Location Pol(781-789)
Integrase(66-74)
DNA(4425..4451)
Pol Epitope Map
Author Location Pol(781-789)
Epitope THLEGKIIL Epitope Alignment
THLEGKIIL epitope logo
Epitope Name TL9
Species (MHC/HLA) human(B*15:17)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60302

Download this epitope record as JSON.

HXB2 Location Pol(781-789)
Integrase(66-74)
DNA(4425..4451)
Pol Epitope Map
Author Location Pol(781-789)
Epitope THLEGKIIL Epitope Alignment
THLEGKIIL epitope logo
Epitope Name TL9
Species (MHC/HLA) human(B*38)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60301

Download this epitope record as JSON.

HXB2 Location Pol(781-789)
Integrase(66-74)
DNA(4425..4451)
Pol Epitope Map
Author Location Pol(781-789)
Epitope THLEGKIIL Epitope Alignment
THLEGKIIL epitope logo
Epitope Name TL9
Species (MHC/HLA) human(B*39)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 61864

Download this epitope record as JSON.

HXB2 Location Pol(781-789)
Integrase(66-74)
DNA(4425..4451)
Pol Epitope Map
Author Location  
Epitope THLEGKIIL Epitope Alignment
THLEGKIIL epitope logo
Epitope Name TL9
Subtype B
Species (MHC/HLA) human(B*39:01)
Immunogen HIV-1 infection, vaccine
Patient MHC/HLA KI-1247: A*11:01, A*31:01, B*15:01, B*39:01, C*04:01, C*07:02
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords vaccine-induced immune responses, novel epitope

Notes

References

Zou2019 Chengcheng Zou, Hayato Murakoshi, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, and Masafumi Takiguchi. Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens. J. Virol., 93(7), 1 Apr 2019. PubMed ID: 30674626. Show all entries for this paper.


Displaying record number 60303

Download this epitope record as JSON.

HXB2 Location Pol(781-789)
Integrase(66-74)
DNA(4425..4451)
Pol Epitope Map
Author Location Pol(781-789)
Epitope THLEGKIIL Epitope Alignment
THLEGKIIL epitope logo
Epitope Name TL9
Species (MHC/HLA) human(C*16)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 61037

Download this epitope record as JSON.

HXB2 Location Pol(781-789)
Integrase(66-74)
DNA(4425..4451)
Pol Epitope Map
Author Location Integrase(66-74)
Epitope THLEGKIIL Epitope Alignment
THLEGKIIL epitope logo
Subtype C
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA CAP045: A*23:01, A*29:02, B*15:10, B*45:01, C*16:01, C*16:02
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords computational prediction, escape, acute/early infection, mutation acquisition

Notes

References

Barton2016 John P. Barton, Nilu Goonetilleke, Thomas C. Butler, Bruce D. Walker, Andrew J. McMichael, and Arup K. Chakraborty. Relative Rate and Location of Intra-Host HIV Evolution to Evade Cellular Immunity Are Predictable. Nat. Commun., 7:11660, 23 May 2016. PubMed ID: 27212475. Show all entries for this paper.


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