HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 55323

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HXB2 Location gp160(767-775)
gp41(256-264)
DNA(8523..8549)
gp160 Epitope Map
Author Location gp41
Epitope SYHRLRDFI Epitope Alignment
SYHRLRDFI epitope logo
Show epitope variants
Epitope Name E
Subtype A
Species (MHC/HLA) mouse(H-2Kd)
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords subtype comparisons, vaccine-induced immune responses, variant cross-reactivity, antagonism

Vaccine Details

Vaccine type DNA with CMV promotor, modified vaccinia Ankara (MVA), DNA prime with modified vaccinia Ankara (MVA) boost
Vaccine strain A clade
Vaccine component Env, Gag, Nef, RT

Notes

References

Larke2007 Natasha Larke, Eung-Jun Im, Ralf Wagner, Carolyn Williamson, Anna-Lise Williamson, Andrew J. McMichael, and Tomáš Hanke. Combined Single-Clade Candidate HIV-1 Vaccines Induce T Cell Responses Limited by Multiple Forms of In Vivo Immune Interference. Eur. J. Immunol., 37(2):566-577, Feb 2007. PubMed ID: 17230443. Show all entries for this paper.


Displaying record number 59108

Download this epitope record as JSON.

HXB2 Location gp160(767-775)
gp41(256-264)
DNA(8523..8549)
gp160 Epitope Map
Author Location gp160(767-775)
Epitope SYHRLRDFI Epitope Alignment
SYHRLRDFI epitope logo
Subtype B
Species (MHC/HLA) human, mouse(H-2d)
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ, CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type DNA
Vaccine strain A clade, B clade, C clade
Vaccine component Env, Gag, Nef, Pol, Tat

Notes

References

Reguzova2015 Alena Reguzova, Denis Antonets, Larisa Karpenko, Alexander Ilyichev, Rinat Maksyutov, and Sergei Bazhan. Design and Evaluation of Optimized Artificial HIV-1 Poly-T Cell-Epitope Immunogens. PLoS One, 10(3):e0116412, 2015. PubMed ID: 25786238. Show all entries for this paper.


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