HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 60644

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HXB2 Location Gag(241-249)
p24(109-117)
DNA(1510..1536)
Gag Epitope Map
Author Location p24(109-117)
Epitope STLQEQIGW Epitope Alignment
STLQEQIGW epitope logo
Epitope Name SW-9
Subtype B, C
Species (MHC/HLA) human(B*57, B*57:01, B*58, B*58:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 2014

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HXB2 Location Gag(241-249)
p24(109-117)
DNA(1510..1536)
Gag Epitope Map
Author Location p24
Epitope STLQEQIGW Epitope Alignment
STLQEQIGW epitope logo
Epitope Name Gag-SW9; p24-SW9
Subtype B
Species (MHC/HLA) human(B*57, B*58)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HAART, ART

Notes

References

Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.


Displaying record number 226

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HXB2 Location Gag(241-249)
p24(109-117)
DNA(1510..1536)
Gag Epitope Map
Author Location Gag(241-249 LAI)
Epitope STLQEQIGW Epitope Alignment
STLQEQIGW epitope logo
Subtype B
Species (MHC/HLA) human(B*57:01, B*58:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords rate of progression

Notes

References

Klein1998 M. R. Klein, S. H. van der Burg, E. Hovenkamp, A. M. Holwerda, J. W. Drijfhout, C. J. Melief, and F. Miedema. Characterization of HLA-B57-Restricted Human Immunodeficiency Virus Type 1 Gag- and RT-Specific Cytotoxic T Lymphocyte Responses. J. Gen. Virol., 79(Pt 9):2191-2201, 1998. PubMed ID: 9747728. Show all entries for this paper.


Displaying record number 53676

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HXB2 Location Gag(241-249)
p24(109-117)
DNA(1510..1536)
Gag Epitope Map
Author Location p24
Epitope STLQEQIGW Epitope Alignment
STLQEQIGW epitope logo
Show epitope variants
Subtype B, D
Species (MHC/HLA) human(B58)
Immunogen HIV-1 infection
Patient MHC/HLA A23, A24, B35, B58, Cw4, Cw7; M11814: A*23, A*24, B*35, B*58, C*04, C*07
Country Democratic Republic of the Congo
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, variant cross-reactivity

Notes

References

Geels2005 Mark J. Geels, Sheri A. Dubey, Kiersten Anderson, Elly Baan, Margreet Bakker, Georgios Pollakis, William A. Paxton, John W. Shiver, and Jaap Goudsmit. Broad Cross-Clade T-Cell Responses to Gag in Individuals Infected with Human Immunodeficiency Virus Type 1 Non-B Clades (A to G): Importance of HLA Anchor Residue Conservation. J. Virol., 79(17):11247-11258, Sep 2005. PubMed ID: 16103177. Show all entries for this paper.


Displaying record number 57019

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HXB2 Location Gag(241-249)
p24(109-117)
DNA(1510..1536)
Gag Epitope Map
Author Location Gag
Epitope STLQEQIGW Epitope Alignment
STLQEQIGW epitope logo
Subtype CRF02_AG
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


Displaying record number 58023

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HXB2 Location Gag(241-249)
p24(109-117)
DNA(1510..1536)
Gag Epitope Map
Author Location Gag
Epitope STLQEQIGW Epitope Alignment
STLQEQIGW epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type adenovirus type 5 (Ad5), DNA prime with Ad5 boost
Vaccine strain B clade IIIB, B clade JRFL, B clade CAM-1
Vaccine component Gag, Nef, Pol

Notes

References

Li2011a Fusheng Li, Adam C. Finnefrock, Sheri A. Dubey, Bette T. M. Korber, James Szinger, Suzanne Cole, M. Juliana McElrath, John W. Shiver, Danilo R. Casimiro, Lawrence Corey, and Steven G Self. Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias Towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study. PLoS One, 6(6):e20479, 2011. PubMed ID: 21695251. Show all entries for this paper.


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