HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 34 matching records:

Displaying record number 60280

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name SV9
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60278

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name SV9
Species (MHC/HLA) human(A*6802)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 53104

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(16-24)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Species (MHC/HLA) human(B*07)
Immunogen HIV-1 infection
Country Spain
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Proliferation
Keywords HAART, ART, supervised treatment interruptions (STI)

Notes

References

Plana2004 Montserrat Plana, Felipe Garcia, Annette Oxenius, Gabriel M. Ortiz, Anna Lopez, Anna Cruceta, Gabriel Mestre, Emilio Fumero, Catherine Fagard, Maria Antonia Sambeat, Ferran Segura, José M. Miró, Mireia Arnedo, L. Lopalcos, Tomas Pumarola, Bernard Hirschel, Rodney E. Phillips, Douglas F. Nixon, Teresa Gallart, and Jose M. Gatell. Relevance of HIV-1-Specific CD4+ Helper T-Cell Responses During Structured Treatment Interruptions in Patients With CD4+ T-Cell Nadir Above 400/mm3. J. Acquir. Immune Defic. Syndr., 36(3):791-799, 1 Jul 2004. PubMed ID: 15213562. Show all entries for this paper.


Displaying record number 58527

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(16-24)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Subtype B
Species (MHC/HLA) human(B*07)
Immunogen HIV-1 infection
Country Canada
Experimental methods Other
Keywords characterizing CD8+ T cells, elite controllers

Notes

References

Peretz2011 Yoav Peretz, Olivia Marra, Réjean Thomas, Danielle Legault, Pierre Côté, Mohamed-Rachid Boulassel, Danielle Rouleau, Jean-Pierre Routy, Rafick-Pierre Sékaly, Christos M Tsoukas, Cécile Tremblay, and Nicole F. Bernard. Relative Contribution of HIV-Specific Functional Lymphocyte Subsets Restricted by Protective and Non-Protective HLA Alleles. Viral Immunol, 24(3):189-198, Jun 2011. PubMed ID: 21668360. Show all entries for this paper.


Displaying record number 59005

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag(73-)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name Gag148
Subtype A
Species (MHC/HLA) human(B*07)
Immunogen HIV-1 infection, vaccine
Country Guinea-Bissau
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type peptide
Vaccine strain A clade
Adjuvant CAF01

Notes

References

Roman2013 Victor Raúl Gómez Román, Kristoffer Jarlov Jensen, Sanne Skov Jensen, Christian Leo-Hansen, Sanne Jespersen, David da Silva Té, Candida Medina Rodrigues, Christoph Mikkel Janitzek, Lasse Vinner, Terese Lea Katzenstein, Peter Andersen, Ingrid Kromann, Lars Vibe Andreasen, Ingrid Karlsson, and Anders Fomsgaard. Therapeutic Vaccination Using Cationic Liposome-Adjuvanted HIV Type 1 Peptides Representing HLA-Supertype-Restricted Subdominant T Cell Epitopes: Safety, Immunogenicity, and Feasibility in Guinea-Bissau. AIDS Res Hum Retroviruses, 29(11):1504-1512, Nov 2013. PubMed ID: 23634822. Show all entries for this paper.


Displaying record number 57525

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(16-24)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name S9WV
Species (MHC/HLA) human, transgenic mouse(B*07)
Immunogen HIV-1 infection, vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, HLA binding
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine strain multiple epitope immunogen
Vaccine component HIV-1

Notes

References

Cardinaud2009 Sylvain Cardinaud, Romain Bouziat, Pierre-Simon Rohrlich, Sophie Tourdot, Laurence Weiss, Pierre Langlade-Demoyen, Anne Burgevin, Susana Fiorentino, Peter van Endert, and François A. Lemonnier. Design of a HIV-1-Derived HLA-B07.02-Restricted Polyepitope Construct. AIDS, 23(15):1945-1954, 24 Sep 2009. PubMed ID: 19644347. Show all entries for this paper.


Displaying record number 1781

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(16-24)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Species (MHC/HLA) human(B*07)
Immunogen HIV-1 infection
Experimental methods  
Keywords rate of progression, acute/early infection

Notes

References

Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.


Displaying record number 1992

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name Gag-SV9; p24-SV9
Subtype B
Species (MHC/HLA) human(B*07, B*81)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HAART, ART

Notes

References

Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.


Displaying record number 59230

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(16-24)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(B*0702)
Immunogen HIV-1 infection
Patient MHC/HLA Subject 8: A*0201, A*2402, B*0702, B*4001, Cw*0304, Cw*0702
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords dynamics, acute/early infection, dendritic cells

Notes

References

Melhem2014 Nada M Melhem, Kellie N. Smith, Xiao-Li Huang, Bonnie A Colleton, Weimin Jiang, Robbie B. Mailliard, James I. Mullins, and Charles R. Rinaldo. The Impact of Viral Evolution and Frequency of Variant Epitopes on Primary and Memory Human Immunodeficiency Virus Type 1-Specific CD8+ T Cell Responses. Virology, 450-451:34-48, Feb 2014. PubMed ID: 24503065. Show all entries for this paper.


Displaying record number 147

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Species (MHC/HLA) human(B*0702)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 59042

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name SV9-p24
Subtype B, C
Species (MHC/HLA) human(B*0702)
Immunogen HIV-1 infection
Country Japan, South Africa, United Kingdom, United States
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, subtype comparisons

Notes

References

Kloverpris2014 Henrik N. Kløverpris, Emily Adland, Madoka Koyanagi, Anette Stryhn, Mikkel Harndahl, Philippa C. Matthews, Roger Shapiro, Bruce D. Walker, Thumbi Ndung'u, Christian Brander, Masafumi Takiguchi, Søren Buus, and Philip Goulder. HIV Subtype Influences HLA-B*07:02-Associated HIV Disease Outcome. AIDS Res. Hum. Retroviruses, 30(5):468-475, May 2014. PubMed ID: 24010680. Show all entries for this paper.


Displaying record number 61972

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Subtype A, D
Species (MHC/HLA) human(B*0702)
Immunogen HIV-1 infection
Patient MHC/HLA 2230: A*0101, A*0301, B*0702, B*5802, Cw*0606, Cw*0702; 2044: A*0308, A*2901, B*0702, B*0801, Cw*0702
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ, Other, Tetramer binding
Keywords HIV exposed persistently seronegative (HEPS), assay or method development

Notes

References

Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.


Displaying record number 61957

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag(148-)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name AV9
Subtype A3 (CRF02_AG+C), B
Species (MHC/HLA) human(B*0702)
Immunogen HIV-1 infection
Patient MHC/HLA 1127: A*0202, A*3002, B*0705, B*1801; 1214: A*0201, A*3402, B*4403, B*8201; 1224: A*3001, B*1503, B*4201
Country Denmark, Guinea-Bissau
Experimental methods HLA binding, Intracellular cytokine staining, Tetramer binding
Keywords binding affinity, vaccine antigen design

Notes

References

Karlsson2012 Ingrid Karlsson, Henrik Kløverpris, Kristoffer Jarlov Jensen, Anette Stryhn, Søren Buus, Annika Karlsson, Lasse Vinner, Philip Goulder, and Anders Fomsgaard. Identification of Conserved Subdominant HIV Type 1 CD8+ T Cell Epitopes Restricted within Common HLA Supertypes for Therapeutic HIV Type 1 Vaccines. AIDS Res. Hum. Retroviruses, 28(11):1434-1443, Nov 2012. PubMed ID: 22747336. Show all entries for this paper.


Displaying record number 54308

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(16-24)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Species (MHC/HLA) human(B*0702)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Cytokine production, HLA binding, Other
Keywords computational epitope prediction, vaccine-induced immune responses, HLA cross-presentation

Notes

References

Reche2006 Pedro A. Reche, Derin B. Keskin, Rebecca E. Hussey, Petronela Ancuta, Dana Gabuzda, and Ellis L. Reinherz. Elicitation from Virus-Naive Individuals of Cytotoxic T Lymphocytes Directed against Conserved HIV-1 Epitopes. Med. Immunol., 5:1, 2006. PubMed ID: 16674822. Show all entries for this paper.


Displaying record number 60630

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(16-24)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name SV-9
Subtype B, C
Species (MHC/HLA) human(B*0702, B*81)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 59446

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name Gag-SV9
Subtype C
Species (MHC/HLA) human(B*4201)
Immunogen HIV-1 infection
Country Botswana, South Africa, United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, Other, Tetramer binding
Keywords immunodominance, optimal epitope

Notes

References

Kloverpris2015 Henrik N Kløverpris, Reuben McGregor, James E. McLaren, Kristin Ladell, Mikkel Harndahl, Anette Stryhn, Jonathan M. Carlson, Catherine Koofhethile, Bram Gerritsen, Can Keşmir, Fabian Chen, Lynn Riddell, Graz Luzzi, Alasdair Leslie, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, David A. Price, and Philip J. Goulder. CD8+ TCR Bias and Immunodominance in HIV-1 Infection. J. Immunol., 194(11):5329-5345, 1 Jun 2015. PubMed ID: 25911754. Show all entries for this paper.


Displaying record number 60281

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name SV9
Species (MHC/HLA) human(B*5802)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 143

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Species (MHC/HLA) human(B7)
Immunogen  
Experimental methods  
Keywords  

Notes

References

Brander1997 Christian Brander and Bruce Walker. Systematic Identification of Optimal HIV-1 CTL Epitopes. In Systematic Identification of Optimal HIV-1 CTL Epitopes. pages IV--1--IV--11. Los Alamos National Laboratory, Theoretical Biology and Biophysics, Los Alamos, New Mexico, 1997. URL: http://hiv-web.lanl.gov/immunology. Show all entries for this paper.


Displaying record number 149

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Brodie2000 S. J. Brodie, B. K. Patterson, D. A. Lewinsohn, K. Diem, D. Spach, P. D. Greenberg, S. R. Riddell, and L. Corey. HIV-Specific Cytotoxic T Lymphocytes Traffic to Lymph Nodes and Localize at Sites of HIV Replication and Cell Death. J. Clin. Invest., 105:1407-1417, 2000. PubMed ID: 10811848. Show all entries for this paper.


Displaying record number 1671

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Species (MHC/HLA) human(B7)
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


Displaying record number 52156

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(16-24)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name B7-SV9
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Patient MHC/HLA A3, B7, Cw7
Experimental methods  
Keywords dynamics, supervised treatment interruptions (STI), acute/early infection

Notes

References

Yu2002b Xu G. Yu, Marylyn M. Addo, Eric S. Rosenberg, William R. Rodriguez, Paul K. Lee, Cecily A. Fitzpatrick, Mary N. Johnston, Daryld. Strick, Philip J. R. Goulder, Bruce D. Walker, and Marcus Altfeld. Consistent Patterns in the Development and Immunodominance of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T-Cell Responses Following Acute HIV-1 Infection. J. Virol., 76(17):8690-8701, Sep 2002. PubMed ID: 12163589. Show all entries for this paper.


Displaying record number 52817

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(16-24)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name B7-SV9 Gag
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords supervised treatment interruptions (STI), escape, early treatment, superinfection

Notes

References

Altfeld2002a Marcus Altfeld, Todd M. Allen, Xu G. Yu, Mary N. Johnston, Deepak Agrawal, Bette T. Korber, David C. Montefiori, David H. O'Connor, Ben T. Davis, Paul K. Lee, Erica L. Maier, Jason Harlow, Philip J. R. Goulder, Christian Brander, Eric S. Rosenberg, and Bruce D. Walker. HIV-1 Superinfection Despite Broad CD8+ T-Cell Responses Containing Replication of the Primary Virus. Nature, 420(6914):434-439, 28 Nov 2002. PubMed ID: 12459786. Show all entries for this paper.


Displaying record number 53030

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, CD8 T-cell Elispot granzyme B
Keywords characterizing CD8+ T cells

Notes

References

Kleen2004 Thomas O. Kleen, Robert Asaad, Samuel J. Landry, Bernhard O. Boehm, and Magdalena Tary-Lehmann. Tc1 Effector Diversity Shows Dissociated Expression of Granzyme B and Interferon-gamma in HIV Infection. AIDS, 18(3):383-392, 20 Feb 2004. PubMed ID: 15090789. Show all entries for this paper.


Displaying record number 54297

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name B7-SV9(p24)
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 55212

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location  
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords supertype, HLA cross-presentation

Notes

References

Frahm2007b Nicole Frahm, Karina Yusim, Todd J. Suscovich, Sharon Adams, John Sidney, Peter Hraber, Hannah S. Hewitt, Caitlyn H. Linde, Daniel G. Kavanagh, Tonia Woodberry, Leah M. Henry, Kellie Faircloth, Jennifer Listgarten, Carl Kadie, Nebojsa Jojic, Kaori Sango, Nancy V. Brown, Eunice Pae, M. Tauheed Zaman, Florian Bihl, Ashok Khatri, Mina John, Simon Mallal, Francesco M. Marincola, Bruce D . Walker, Alessandro Sette, David Heckerman, Bette T. Korber, and Christian Brander. Extensive HLA Class I Allele Promiscuity among Viral CTL Epitopes. Eur. J. Immunol., 37(9):2419-2433, Sep 2007. PubMed ID: 17705138. Show all entries for this paper.


Displaying record number 56437

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name SV9(p24)
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 58418

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name Gag148
Subtype B, CRF02_AG
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Country Cote D'Ivoire, Denmark, Ghana, Guinea-Bissau, Mali, Senegal
Experimental methods Intracellular cytokine staining, Pentamer labeling
Keywords vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.

Vinner2011 Lasse Vinner, Birgitta Holmgren, Kristoffer J. Jensen, Joakim Esbjornsson, Marie Borggren, Julie L. Hentze, Ingrid Karlsson, Betina S. Andresen, Gregers J. Gram, Henrik Kloverpris, Peter Aaby, Zacarias José Da Silva, Eva-Maria Fenyö, and Anders Fomsgaard. Sequence Analysis of HIV-1 Isolates from Guinea-Bissau: Selection of Vaccine Epitopes Relevant in Both West African and European Countries. APMIS, 119(8):487-497, Aug 2011. PubMed ID: 21749448. Show all entries for this paper.


Displaying record number 148

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag( subtype B)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Subtype B
Species (MHC/HLA) human(B*8101, B7)
Immunogen HIV-1 exposed seronegative
Experimental methods  
Keywords subtype comparisons

Notes

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 146

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24( subtype B)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Subtype B
Species (MHC/HLA) human(B*8101, B7)
Immunogen HIV-1 exposed seronegative
Experimental methods  
Keywords  

Notes

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.


Displaying record number 60279

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name SV9
Species (MHC/HLA) human(B*81)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 56589

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(148-156)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Epitope Name SV9
Subtype C
Species (MHC/HLA) human(B*8101)
Immunogen HIV-1 infection
Country South Africa, Zambia
Experimental methods  
Keywords viral fitness and reversion, HLA associated polymorphism

Notes

References

Goepfert2008 Paul A. Goepfert, Wendy Lumm, Paul Farmer, Philippa Matthews, Andrew Prendergast, Jonathan M. Carlson, Cynthia A. Derdeyn, Jianming Tang, Richard A. Kaslow, Anju Bansal, Karina Yusim, David Heckerman, Joseph Mulenga, Susan Allen, Philip J. R. Goulder, and Eric Hunter. Transmission of HIV-1 Gag Immune Escape Mutations Is Associated with Reduced Viral Load in Linked Recipients. J. Exp. Med., 205(5):1009-1017, 12 May 2008. PubMed ID: 18426987. Show all entries for this paper.


Displaying record number 58443

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24(16-24)
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Subtype A1
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Proliferation
Keywords assay or method development, characterizing CD8+ T cells

Notes

References

Richmond2011 Meika Richmond, Lyle R. McKinnon, Sandra A. Koesters Kiazyk, Charles Wachihi, Makobu Kimani, Joshua Kimani, Francis A. Plummer, and T. Blake Ball. Epitope Mapping of HIV-Specific CD8+ T Cell Responses by Multiple Immunological Readouts Reveals Distinct Specificities Defined by Function. J. Virol., 85(3):1275-1286, Feb 2011. PubMed ID: 21084478. Show all entries for this paper.


Displaying record number 57016

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location Gag
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Subtype D
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


Displaying record number 144

HXB2 Location Gag(148-156)
p24(16-24)
DNA(1231..1257)
Gag Epitope Map
Author Location p24
Epitope SPRTLNAWV Epitope Alignment
SPRTLNAWV epitope logo
Species (MHC/HLA) chimpanzee
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Santra1999 S. Santra, P. N. Fultz, and N. L. Letvin. Virus-Specific Cytotoxic T Lymphocytes in Human Immunodeficiency Virus Type 1-Infected Chimpanzees. J. Virol., 73:7065-7069, 1999. PubMed ID: 10400811. Show all entries for this paper.


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