HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 8 matching records:

Displaying record number 1501

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HXB2 Location Pol(311-320)
RT(156-165)
DNA(3015..3044)
Pol Epitope Map
Author Location RT(311-319 SF2)
Epitope SPAIFQSSMT Epitope Alignment
SPAIFQSSMT epitope logo
Epitope Name P4
Species (MHC/HLA) human(B*07)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART

Notes

References

Mollet2000 L. Mollet, T. S. Li, A. Samri, C. Tournay, R. Tubiana, V. Calvez, P. Debre, C. Katlama, and B. Autran. Dynamics of HIV-specific CD8+ T lymphocytes with changes in viral load. J. Immunol., 165(3):1692-704, 1 Aug 2000. URL: http://www.jimmunol.org/v165n3/1692/1692-abs-frame.html. PubMed ID: 10903781. Show all entries for this paper.


Displaying record number 53108

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HXB2 Location Pol(311-320)
RT(156-165)
DNA(3015..3044)
Pol Epitope Map
Author Location RT Pol(311-319)
Epitope SPAIFQSSMT Epitope Alignment
SPAIFQSSMT epitope logo
Species (MHC/HLA) human(B*07)
Immunogen HIV-1 infection
Country Spain
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Proliferation
Keywords HAART, ART, supervised treatment interruptions (STI)

Notes

References

Plana2004 Montserrat Plana, Felipe Garcia, Annette Oxenius, Gabriel M. Ortiz, Anna Lopez, Anna Cruceta, Gabriel Mestre, Emilio Fumero, Catherine Fagard, Maria Antonia Sambeat, Ferran Segura, José M. Miró, Mireia Arnedo, L. Lopalcos, Tomas Pumarola, Bernard Hirschel, Rodney E. Phillips, Douglas F. Nixon, Teresa Gallart, and Jose M. Gatell. Relevance of HIV-1-Specific CD4+ Helper T-Cell Responses During Structured Treatment Interruptions in Patients With CD4+ T-Cell Nadir Above 400/mm3. J. Acquir. Immune Defic. Syndr., 36(3):791-799, 1 Jul 2004. PubMed ID: 15213562. Show all entries for this paper.


Displaying record number 57530

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HXB2 Location Pol(311-320)
RT(156-165)
DNA(3015..3044)
Pol Epitope Map
Author Location RT(156-165)
Epitope SPAIFQSSMT Epitope Alignment
SPAIFQSSMT epitope logo
Epitope Name S10MT
Species (MHC/HLA) human, transgenic mouse(B*07)
Immunogen HIV-1 infection, vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, HLA binding
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type polyepitope
Vaccine strain multiple epitope immunogen
Vaccine component HIV-1

Notes

References

Cardinaud2009 Sylvain Cardinaud, Romain Bouziat, Pierre-Simon Rohrlich, Sophie Tourdot, Laurence Weiss, Pierre Langlade-Demoyen, Anne Burgevin, Susana Fiorentino, Peter van Endert, and François A. Lemonnier. Design of a HIV-1-Derived HLA-B07.02-Restricted Polyepitope Construct. AIDS, 23(15):1945-1954, 24 Sep 2009. PubMed ID: 19644347. Show all entries for this paper.


Displaying record number 1470

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HXB2 Location Pol(311-320)
RT(156-165)
DNA(3015..3044)
Pol Epitope Map
Author Location RT(311-319 LAI)
Epitope SPAIFQSSMT Epitope Alignment
SPAIFQSSMT epitope logo
Show epitope variants
Epitope Name P4
Subtype B
Species (MHC/HLA) human(B35)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, escape

Notes

References

Samri2000 A. Samri, G. Haas, J. Duntze, J. M. Bouley, V. Calvez, C. Katlama, and B. Autran. Immunogenicity of mutations induced by nucleoside reverse transcriptase inhibitors for human immunodeficiency virus type 1-specific cytotoxic T cells. J. Virol., 74(19):9306-12, Oct 2000. URL: http://jvi.asm.org/cgi/content/full/74/19/9306. PubMed ID: 10982378. Show all entries for this paper.


Displaying record number 52069

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HXB2 Location Pol(311-320)
RT(156-165)
DNA(3015..3044)
Pol Epitope Map
Author Location RT( IIIB)
Epitope SPAIFQSSMT Epitope Alignment
SPAIFQSSMT epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods  
Keywords epitope processing, escape

Notes

References

Moore2002b Corey B. Moore, Mina John, Ian R. James, Frank T. Christiansen, Campbell S. Witt, and Simon A. Mallal. Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level. Science, 296(5572):1439-1443, 24 May 2002. PubMed ID: 12029127. Show all entries for this paper.


Displaying record number 1628

Download this epitope record as JSON.

HXB2 Location Pol(311-320)
RT(156-165)
DNA(3015..3044)
Pol Epitope Map
Author Location Pol
Epitope SPAIFQSSMT Epitope Alignment
SPAIFQSSMT epitope logo
Species (MHC/HLA) human(B7)
Immunogen  
Experimental methods  
Keywords  

Notes

References

DeGroot2001 A. S. De Groot, A. Bosma, N. Chinai, J. Frost, B. M. Jesdale, M. A. Gonzalez, W. Martin, and C. Saint-Aubin. From genome to vaccine: in silico predictions, ex vivo verification. Vaccine, 19(31):4385-95, 14 Aug 2001. PubMed ID: 11483263. Show all entries for this paper.


Displaying record number 443

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HXB2 Location Pol(311-320)
RT(156-165)
DNA(3015..3044)
Pol Epitope Map
Author Location RT(311-319 SF2)
Epitope SPAIFQSSMT Epitope Alignment
SPAIFQSSMT epitope logo
Species (MHC/HLA) human(B7)
Immunogen  
Experimental methods  
Keywords review

Notes

References

Brander1997 Christian Brander and Bruce Walker. Systematic Identification of Optimal HIV-1 CTL Epitopes. In Systematic Identification of Optimal HIV-1 CTL Epitopes. pages IV--1--IV--11. Los Alamos National Laboratory, Theoretical Biology and Biophysics, Los Alamos, New Mexico, 1997. URL: http://hiv-web.lanl.gov/immunology. Show all entries for this paper.

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.


Displaying record number 52885

Download this epitope record as JSON.

HXB2 Location Pol(311-320)
RT(156-165)
DNA(3015..3044)
Pol Epitope Map
Author Location Pol
Epitope SPAIFQSSMT Epitope Alignment
SPAIFQSSMT epitope logo
Epitope Name 1306
Subtype multiple
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Patient MHC/HLA A24, A3, B38, B7, Cw7
Country United States
Experimental methods T-cell Elispot
Keywords binding affinity, computational epitope prediction

Notes

References

DeGroot2003 Anne S. De Groot, Bill Jesdale, William Martin, Caitlin Saint Aubin, Hakima Sbai, Andrew Bosma, Judy Lieberman, Gail Skowron, Fadi Mansourati, and Kenneth H. Mayer. Mapping Cross-Clade HIV-1 Vaccine Epitopes Using a Bioinformatics Approach. Vaccine, 21(27-30):4486-4504, 1 Oct 2003. PubMed ID: 14505932. Show all entries for this paper.


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