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HIV Molecular Immunology Database

Search CTL/CD8+ T-Cell Epitope Database

Found 7 matching records:

Displaying record number 57298

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HXB2 Location Gag(77-86)
p17(77-86)
DNA(1018..1047)
Gag Epitope Map
Author Location p17(77-86)
Epitope SLYNTVATLY Epitope Alignment
SLYNTVATLY epitope logo
Show epitope variants
Epitope Name SY10
Subtype B
Species (MHC/HLA) human(A*02)
Immunogen peptide-HLA interaction
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Other
Keywords epitope processing

Notes

References

Tenzer2009 Stefan Tenzer, Edmund Wee, Anne Burgevin, Guillaume Stewart-Jones, Lone Friis, Kasper Lamberth, Chih-hao Chang, Mikkel Harndahl, Mirjana Weimershaus, Jan Gerstoft, Nadja Akkad, Paul Klenerman, Lars Fugger, E. Yvonne Jones, Andrew J. McMichael, Søren Buus, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. Antigen Processing Influences HIV-Specific Cytotoxic T Lymphocyte Immunodominance. Nat. Immunol., 10(6):636-646, Jun 2009. PubMed ID: 19412183. Show all entries for this paper.


Displaying record number 55232

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HXB2 Location Gag(77-86)
p17(77-86)
DNA(1018..1047)
Gag Epitope Map
Author Location p17(77-85)
Epitope SLYNTVATLY Epitope Alignment
SLYNTVATLY epitope logo
Subtype B
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords assay or method development, optimal epitope

Notes

References

Wang2007 Shaoyang Wang, Yongtao Sun, Song Zhai, Yan Zhuang, Shuguang Zhao, Whenzhen Kang, Xinhong Li, Dedong Huang, Xu G. Yu, Bruce D. Walker, and Marcus A. Altfeld. Identification of HLA-A11-Restricted HIV-1-Specific Cytotoxic T-Lymphocyte Epitopes in China. Curr. HIV Res., 5(1):119-128, Jan 2007. PubMed ID: 17266563. Show all entries for this paper.


Displaying record number 58647

Download this epitope record as JSON.

HXB2 Location Gag(77-86)
p17(77-86)
DNA(1018..1047)
Gag Epitope Map
Author Location  
Epitope SLYNTVATLY Epitope Alignment
SLYNTVATLY epitope logo
Epitope Name SY10
Subtype B
Species (MHC/HLA) human(A*02:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope, A-list

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 52875

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HXB2 Location Gag(77-86)
p17(77-86)
DNA(1018..1047)
Gag Epitope Map
Author Location Gag
Epitope SLYNTVATLY Epitope Alignment
SLYNTVATLY epitope logo
Epitope Name 1261
Subtype multiple
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Patient MHC/HLA A1, A2, B8, C*16; A2, A30, B35, B49, Cw4, Cw7; A2, A3, B58, B7, Cw7; A2, A3, B51, B8, Cw1, Cw7
Country United States
Experimental methods T-cell Elispot
Keywords binding affinity, computational prediction

Notes

References

DeGroot2003 Anne S. De Groot, Bill Jesdale, William Martin, Caitlin Saint Aubin, Hakima Sbai, Andrew Bosma, Judy Lieberman, Gail Skowron, Fadi Mansourati, and Kenneth H. Mayer. Mapping Cross-Clade HIV-1 Vaccine Epitopes Using a Bioinformatics Approach. Vaccine, 21(27-30):4486-4504, 1 Oct 2003. PubMed ID: 14505932. Show all entries for this paper.


Displaying record number 55181

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HXB2 Location Gag(77-86)
p17(77-86)
DNA(1018..1047)
Gag Epitope Map
Author Location  
Epitope SLYNTVATLY Epitope Alignment
SLYNTVATLY epitope logo
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Tetramer binding
Keywords responses in children, rate of progression

Notes

References

Chakraborty2005 Rana Chakraborty, Anne-Sophie Morel, Julian K. Sutton, Victor Appay, Ruth M. Ripley, Tao Dong, Tim Rostron, Simon Ogola, Tresa Palakudy, Rachel Musoke, Angelo D'Agostino, Mary Ritter, and Sarah L. Rowland-Jones. Correlates of Delayed Disease Progression in HIV-1-Infected Kenyan Children. J. Immunol., 174(12):8191-8199, 15 Jun 2005. PubMed ID: 15944328. Show all entries for this paper.


Displaying record number 62887

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HXB2 Location Gag(77-86)
p17(77-86)
DNA(1018..1047)
Gag Epitope Map
Author Location Gag
Epitope SLYNTVATLY Epitope Alignment
SLYNTVATLY epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection, vaccine
Experimental methods Other
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type polyepitope, adenovirus type 5 (Ad5)
Vaccine component Gag, Nef, Pol

Notes

References

Boppana2020 Sushma Boppana, Andrew Fiore-Gartland, Anju Bansal, and Paul Goepfert. Cross-Reactive CD8 T-Cell Responses Elicited by Adenovirus Type 5-Based HIV-1 Vaccines Contributed to Early Viral Evolution in Vaccine Recipients Who Became Infected. J. Virol, 94(2), 6 Jan 2020. PubMed ID: 31645444. Show all entries for this paper.


Displaying record number 62777

Download this epitope record as JSON.

HXB2 Location Gag(77-86)
p17(77-86)
DNA(1018..1047)
Gag Epitope Map
Author Location p17(77-86)
Epitope SLYNTVATLY Epitope Alignment
SLYNTVATLY epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen engineered
Experimental methods Other, Relative replication capacity assay
Keywords assay or method development, protective allele

Notes

References

Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.


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