HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 52667

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HXB2 Location Vpr(41-49)
DNA(5679..5705)
Vpr Epitope Map
Author Location Vpr
Epitope SLGQHIYET Epitope Alignment
SLGQHIYET epitope logo
Epitope Name Vpr41
Species (MHC/HLA) human, transgenic mouse(A2)
Immunogen HIV-1 infection, vaccine
Experimental methods Chromium-release assay, Flow cytometric T-cell cytokine assay, T-cell Elispot
Keywords binding affinity, subtype comparisons, computational epitope prediction

Vaccine Details

Vaccine type peptide
Vaccine component anchored gp120, Vpr
Adjuvant Incomplete Freund's Adjuvant (IFA)

Notes

References

Corbet2003 Sylvie Corbet, Henrik Vedel Nielsen, Lasse Vinner, Sanne Lauemoller, Dominic Therrien, Sheila Tang, Gitte Kronborg, Lars Mathiesen, Paul Chaplin, Søren Brunak, Søren Buus, and Anders Fomsgaard. Optimization and Immune Recognition of Multiple Novel Conserved HLA-A2, Human Immunodeficiency Virus Type 1-Specific CTL Epitopes. J. Gen. Virol., 84(Pt 9):2409-2421, Sep 2003. PubMed ID: 12917462. Show all entries for this paper.


Displaying record number 55391

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HXB2 Location Vpr(41-49)
DNA(5679..5705)
Vpr Epitope Map
Author Location  
Epitope SLGQHIYET Epitope Alignment
SLGQHIYET epitope logo
Show epitope variants
Epitope Name Vpr 41
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country Denmark
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords computational epitope prediction, immunodominance, escape, variant cross-reactivity

Notes

References

Thorn2007 Mette Thorn, Sheila Tang, Dominic Therrien, Henrik Kløverpris, Lasse Vinner, Gitte Kronborg, Jan Gerstoft, Sylvie Corbet, and Anders Fomsgaard. Sequence Conservation of Subdominant HLA-A2-Binding CTL Epitopes in HIV-1 Clinical Isolates and CD8+ T-Lymphocyte Cross-Recognition May Explain the Immune Reaction in Infected Individuals. APMIS, 115(6):757-768, Jun 2007. PubMed ID: 17550385. Show all entries for this paper.


Displaying record number 55801

Download this epitope record as JSON.

HXB2 Location Vpr(41-49)
DNA(5679..5705)
Vpr Epitope Map
Author Location Vpr(41-49)
Epitope SLGQHIYET Epitope Alignment
SLGQHIYET epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords computational epitope prediction, HLA associated polymorphism

Notes

References

Srinivasan2008 Alagarsamy Srinivasan, Velpandi Ayyavoo, Sundarasamy Mahalingam, Aarthi Kannan, Anne Boyd, Debduti Datta, Vaniambadi S. Kalyanaraman, Anthony Cristillo, Ronald G. Collman, Nelly Morellet, Bassel E. Sawaya, and Ramachandran Murali. A Comprehensive Analysis of the Naturally Occurring Polymorphisms in HIV-1 Vpr: Potential Impact on CTL Epitopes. Virol. J., 5:99, 2008. PubMed ID: 18721481. Show all entries for this paper.


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