HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 12 matching records:

Displaying record number 55756

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location Gag
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Epitope Name SFL9
Species (MHC/HLA) human(A*02)
Immunogen  
Experimental methods Other
Keywords TCR usage

Notes

References

Frankild2008 Sune Frankild, Rob J. de Boer, Ole Lund, Morten Nielsen, and Can Kesmir. Amino Acid Similarity Accounts for T Cell Cross-Reactivity and for ``holes'' in the T Cell Repertoire. PLoS ONE, 3(3):e1831, 2008. PubMed ID: 18350167. Show all entries for this paper.


Displaying record number 57623

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location p17
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Subtype A
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses

Notes

References

Howles2010 Sarah Howles, Ana Guimarães-Walker, Hongbing Yang, Gemma Hancock, Katalin di Gleria, Tony Tarragona-Fiol, Peter Hayes, Jill Gilmour, Anne Bridgeman, Tomáš Hanke, Andrew McMichael, and Lucy Dorrell. Vaccination with a Modified Vaccinia Virus Ankara (MVA)-Vectored HIV-1 Immunogen Induces Modest Vector-Specific T Cell Responses in Human Subjects. Vaccine, 28(45):7306-7312, 21 Oct 2010. PubMed ID: 20816902. Show all entries for this paper.


Displaying record number 56349

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location Gag(77-85)
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Subtype C
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Country Canada, South Africa
Experimental methods  
Keywords escape

Notes

References

Carlson2008 Jonathan M. Carlson, Zabrina L. Brumme, Christine M. Rousseau, Chanson J. Brumme, Philippa Matthews, Carl Kadie, James I. Mullins, Bruce D. Walker, P. Richard Harrigan, Philip J. R. Goulder, and David Heckerman. Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag. PLoS Comput Biol, 4(11):e1000225, Nov 2008. PubMed ID: 19023406. Show all entries for this paper.


Displaying record number 59229

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location Gag(77-85)
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(A*02:01)
Immunogen HIV-1 infection
Patient MHC/HLA Subject 8: A*02:01, A*24:02, B*07:02, B*40:01, C*03:04, C*07:02
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords dynamics, acute/early infection, dendritic cells

Notes

References

Melhem2014 Nada M Melhem, Kellie N. Smith, Xiao-Li Huang, Bonnie A Colleton, Weimin Jiang, Robbie B. Mailliard, James I. Mullins, and Charles R. Rinaldo. The Impact of Viral Evolution and Frequency of Variant Epitopes on Primary and Memory Human Immunodeficiency Virus Type 1-Specific CD8+ T Cell Responses. Virology, 450-451:34-48, Feb 2014. PubMed ID: 24503065. Show all entries for this paper.


Displaying record number 55362

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location (77-85)
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Epitope Name 3F
Species (MHC/HLA) human(A*02:01)
Immunogen in vitro stimulation or selection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, HLA binding, Tetramer binding
Keywords binding affinity, immunodominance, dendritic cells

Notes

References

Schaubert2007 Keri L. Schaubert, David A. Price, Nicole Frahm, Jinzhu Li, Hwee L. Ng, Aviva Joseph, Elyse Paul, Biswanath Majumder, Velpandi Ayyavoo, Emma Gostick, Sharon Adams, Francesco M. Marincola, Andrew K. Sewell, Marcus Altfeld, Jason M. Brenchley, Daniel C. Douek, Otto O. Yang, Christian Brander, Harris Goldstein, and June Kan-Mitchell. Availability of a Diversely Avid CD8+ T Cell Repertoire Specific for the Subdominant HLA-A2-Restricted HIV-1 Gag p24(19-27) Epitope. J. Immunol., 178(12):7756-7766, 15 Jun 2007. PubMed ID: 17548613. Show all entries for this paper.


Displaying record number 102

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location p17(77-85 subtype A)
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Show epitope variants
Epitope Name SL9
Subtype A
Species (MHC/HLA) human(A*02:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons

Notes

References

Dorrell1999 L. Dorrell, T. Dong, G. S. Ogg, S. Lister, S. McAdam, T. Rostron, C. Conlon, A. J. McMichael, and S. L. Rowland-Jones. Distinct Recognition of Non-Clade B Human Immunodeficiency Virus Type 1 Epitopes by Cytotoxic T Lymphocytes Generated from Donors Infected in Africa. J. Virol., 73:1708-1714, 1999. PubMed ID: 9882385. Show all entries for this paper.


Displaying record number 54763

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location Gag
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Epitope Name A2-SL9 Gag (77-85)
Subtype B
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Patient MHC/HLA A2, A3, B60, B7
Country France
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords binding affinity, immunodominance, TCR usage, characterizing CD8+ T cells

Notes

References

Almeida2007 Jorge R. Almeida, David A. Price, Laura Papagno, Zaïna Aït Arkoub, Delphine Sauce, Ethan Bornstein, Tedi E. Asher, Assia Samri, Aurélie Schnuriger, Ioannis Theodorou, Dominique Costagliola, Christine Rouzioux, Henri Agut, Anne-Geneviève Marcelin, Daniel Douek, Brigitte Autran, and Victor Appay. Superior Control of HIV-1 Replication by CD8+ T Cells Is Reflected by their Avidity, Polyfunctionality, and Clonal Turnover. J. Exp. Med., 204(10):2473-2485, 1 Oct 2007. PubMed ID: 17893201. Show all entries for this paper.


Displaying record number 53411

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location p17(77-85)
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Show epitope variants
Epitope Name SLF
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Patient MHC/HLA A2, A68.1, B*07, B*35:03, C*04:01, C*07:02, DQ2, DQ6, DR15, DR17, DR51, DR52
Experimental methods CD4 T-cell Elispot - IFNγ, CD8 T-cell Elispot - IFNγ, Tetramer binding
Keywords rate of progression, immunodominance, escape

Notes

References

Oxenius2004 Annette Oxenius, David A. Price, Alexandra Trkola, Charles Edwards, Emma Gostick, Hua-Tang Zhang, Philippa J. Easterbrook, Tin Tun, Andrew Johnson, Anele Waters, Edward C. Holmes, and Rodney E. Phillips. Loss of Viral Control in Early HIV-1 Infection Is Temporally Associated with Sequential Escape from CD8+ T Cell Responses and Decrease in HIV-1-Specific CD4+ and CD8+ T Cell Frequencies. J. Infect. Dis., 190(4):713-721, 15 Aug 2004. PubMed ID: 15272399. Show all entries for this paper.


Displaying record number 57213

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location Gag
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords mother-to-infant transmission

Notes

References

Lohman-Payne2009 B. Lohman-Payne, J. A. Slyker, B. A. Richardson, C. Farquhar, M. Majiwa, E. Maleche-Obimbo, D. Mbori-Ngacha, J. Overbaugh, S. Rowland-Jones, and G. John-Stewart. Infants with Late Breast Milk Acquisition of HIV-1 Generate Interferon-gamma Responses More Rapidly than Infants with Early Peripartum Acquisition. Clin. Exp. Immunol., 156(3):511-517, Jun 2009. PubMed ID: 19438605. Show all entries for this paper.


Displaying record number 1649

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location p17(77-85)
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Show epitope variants
Species (MHC/HLA) human(A2)
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords subtype comparisons, HIV exposed persistently seronegative (HEPS), immunodominance

Notes

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


Displaying record number 55409

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HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location  
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Species (MHC/HLA) human(A2)
Immunogen peptide-HLA interaction
Experimental methods  
Keywords HLA cross-presentation

Notes

References

Li2008 Fusheng Li, Denise M. McKenney, Uma Malhotra, Claire Crimi, Jessica Nolin, Lawrence Corey, Juliana M. McElrath, Mark J. Newman, and Steven G. Self. Towards Prediction of Degenerate CTL Epitope Recognition. Hum. Vaccin., 4(2):115-121, Mar-Apr 2008. PubMed ID: 18382130. Show all entries for this paper.


Displaying record number 55762

Download this epitope record as JSON.

HXB2 Location Gag(77-85)
p17(77-85)
DNA(1018..1044)
Gag Epitope Map
Author Location p17
Epitope SLFNTVATL Epitope Alignment
SLFNTVATL epitope logo
Epitope Name SL9(p17)
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords immunodominance, optimal epitope, chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


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