HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 59183

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HXB2 Location Nef(188-196)
DNA(9358..9384)
Nef Epitope Map
Author Location Nef(188-196 NL432)
Epitope SLAFRHVAR Epitope Alignment
SLAFRHVAR epitope logo
Subtype B
Species (MHC/HLA) human(A*31)
Immunogen HIV-1 infection
Patient MHC/HLA AC05: A*24:02, A*31:01, B*39:01, B*52:01, C*07:02, C*12:02; AC08: A*02:01, A*31:01, B*08:01, B*44:02, C*05, C*07
Country Australia, Germany, United States
Experimental methods Other
Keywords class I down-regulation by Nef, acute/early infection

Notes

References

Kuang2014 Xiaomei T. Kuang, Xiaoguang Li, Gursev Anmole, Philip Mwimanzi, Aniqa Shahid, Anh Q. Le, Louise Chong, Hua Qian, Toshiyuki Miura, Tristan Markle, Bemuluyigza Baraki, Elizabeth Connick, Eric S. Daar, Heiko Jessen, Anthony D. Kelleher, Susan Little, Martin Markowitz, Florencia Pereyra, Eric S. Rosenberg, Bruce D. Walker, Takamasa Ueno, Zabrina L. Brumme, and Mark A. Brockman. Impaired Nef Function Is Associated with Early Control of HIV-1 Viremia. J. Virol., 88(17):10200-10213, 1 Sep 2014. PubMed ID: 24965469. Show all entries for this paper.


Displaying record number 56635

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HXB2 Location Nef(188-196)
DNA(9358..9384)
Nef Epitope Map
Author Location Nef(187-196)
Epitope SLAFRHVAR Epitope Alignment
SLAFRHVAR epitope logo
Show epitope variants
Species (MHC/HLA) human(A*31:01)
Immunogen HIV-1 infection
Patient MHC/HLA A*02:01, A*31:01, B*40:01, B*44:02, C*03:02, C*05:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords escape, acute/early infection, novel epitope

Notes

References

Goonetilleke2009 Nilu Goonetilleke, Michael K. P. Liu, Jesus F. Salazar-Gonzalez, Guido Ferrari, Elena Giorgi, Vitaly V. Ganusov, Brandon F. Keele, Gerald H. Learn, Emma L. Turnbull, Maria G Salazar, Kent J Weinhold, Stephen Moore, CHAVI Clinical Core B, Norman Letvin, Barton F. Haynes, Myron S. Cohen, Peter Hraber, Tanmoy Bhattacharya, Persephone Borrow, Alan S. Perelson, Beatrice H. Hahn, George M. Shaw, Bette T. Korber, and Andrew J. McMichael. The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. J. Exp. Med., 206(6):1253-1272, 8 Jun 2009. PubMed ID: 19487423. Show all entries for this paper.


Displaying record number 62130

Download this epitope record as JSON.

HXB2 Location Nef(188-196)
DNA(9358..9384)
Nef Epitope Map
Author Location Nef(188-196)
Epitope SLAFRHVAR Epitope Alignment
SLAFRHVAR epitope logo
Show epitope variants
Species (MHC/HLA) human(A*31:01)
Immunogen HIV-1 infection
Experimental methods Other, Relative replication capacity assay
Keywords escape

Notes

References

Barton2019 John P. Barton, Erasha Rajkoomar, Jaclyn K. Mann, Dariusz K. Murakowski, Mako Toyoda, Macdonald Mahiti, Phillip Mwimanzi, Takamasa Ueno, Arup K. Chakraborty, and Thumbi Ndung'u. Modelling and In Vitro Testing of the HIV-1 Nef Fitness Landscape. Virus Evol., 5(2):vez029, Jul 2019. PubMed ID: 31392033. Show all entries for this paper.


Displaying record number 57431

Download this epitope record as JSON.

HXB2 Location Nef(188-196)
DNA(9358..9384)
Nef Epitope Map
Author Location Nef
Epitope SLAFRHVAR Epitope Alignment
SLAFRHVAR epitope logo
Show epitope variants
Epitope Name SR9
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country United States
Experimental methods  
Keywords escape, acute/early infection

Notes

References

Fischer2010 Will Fischer, Vitaly V. Ganusov, Elena E. Giorgi, Peter T. Hraber, Brandon F. Keele, Thomas Leitner, Cliff S. Han, Cheryl D. Gleasner, Lance Green, Chien-Chi Lo, Ambarish Nag, Timothy C. Wallstrom, Shuyi Wang, Andrew J. McMichael, Barton F. Haynes, Beatrice H. Hahn, Alan S. Perelson, Persephone Borrow, George M. Shaw, Tanmoy Bhattacharya, and Bette T. Korber. Transmission of Single HIV-1 Genomes and Dynamics of Early Immune Escape Revealed by Ultra-Deep Sequencing. PLoS One, 5(8):e12303, 2010. PubMed ID: 20808830. Show all entries for this paper.


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