HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 27 matching records:

Displaying record number 60256

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location Env(375-383)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Epitope Name SF9
Species (MHC/HLA) human(A*23)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 52996

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120(375-383)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Show epitope variants
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Patient MHC/HLA A3, A32, B15, B51, Cw03, Cw6, DQ7, DR4, DR8
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, escape

Notes

References

Geels2003 Mark J. Geels, Marion Cornelissen, Hanneke Schuitemaker, Kiersten Anderson, David Kwa, Jolanda Maas, John T. Dekker, Elly Baan, Fokla Zorgdrager, Remco van den Burg, Martijn van Beelen, Vladimir V. Lukashov, Tong-Ming Fu, William A. Paxton, Lia van der Hoek, Sheri A. Dubey, John W. Shiver, and Jaap Goudsmit. Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual. J. Virol., 77(23):12430-12440, Dec 2003. PubMed ID: 14610167. Show all entries for this paper.


Displaying record number 56006

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Epitope Name SF9(gp120)
Subtype B
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 1569

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120(375-383 SF2)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.


Displaying record number 55136

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120(375-383)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Show epitope variants
Species (MHC/HLA) human(B*1516, B15, B63)
Immunogen  
Experimental methods  
Keywords subtype comparisons, viral fitness and reversion

Notes

References

Queiroz2007 Artur Trancoso Lopo de Queiroz, Luciane Amorim Santos, Domingos Ramon Moreau, Tulio de Oliveira, David I. Watkins, Bernardo Galvão-Castro, and Luiz Carlos Junior Alcantara. Identification and Characterization of Previously Described Epitopes in HIV-1 Subtypes B, C, F and BF in Brazil. Braz. J. Infect. Dis., 11(1):27-30, Feb 2007. PubMed ID: 17625722. Show all entries for this paper.


Displaying record number 779

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120(375-383 IIIB)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Species (MHC/HLA) human(B15, B63)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Wilson1997 C. C. Wilson, S. A. Kalams, B. M. Wilkes, D. J. Ruhl, F. Gao, B. H. Hahn, I. C. Hanson, K. Luzuriaga, S. Wolinsky, R. Koup, S. P. Buchbinder, R. P. Johnson, and B. D. Walker. Overlapping Epitopes in Human Immunodeficiency Virus Type 1 gp120 Presented by HLA A, B, and C Molecules: Effects of Viral Variation on Cytotoxic T-Lymphocyte Recognition. J. Virol., 71:1256-1264, 1997. CTL clones were isolated from four individuals that interact with the same 25 amino-acid peptide using three different HLA presenting molecules. PubMed ID: 8995649. Show all entries for this paper.


Displaying record number 55838

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location Env(375-383)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Species (MHC/HLA) human(B15, Cw*0401, Cw*0407, Cw4)
Immunogen HIV-1 infection
Country Philippines, Taiwan
Experimental methods  
Keywords escape

Notes

References

Liang2008 Binhua Liang, Ma Luo, T Blake Ball, Xiaojian Yao, Gary Van Domselaar, Wilfred R. Cuff, Mary Cheang, Steven J. M. Jones, and Francis A. Plummer. Systematic Analysis of Host Immunological Pressure on the Envelope Gene of Human Immunodeficiency Virus Type 1 by an Immunobioinformatics Approach. Curr. HIV Res., 6(4):370-379, Jun 2008. PubMed ID: 18691035. Show all entries for this paper.


Displaying record number 53911

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location Env
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Subtype B
Species (MHC/HLA) human(B*1516)
Immunogen HIV-1 infection
Patient MHC/HLA A*0202, A*0301, B*0702, B*1516
Country United States
Experimental methods  
Keywords escape, acute/early infection

Notes

References

Bernardin2005 Flavien Bernardin, Denice Kong, Lorraine Peddada, Lee Ann Baxter-Lowe, and Eric Delwart. Human Immunodeficiency Virus Mutations During the First Month of Infection are Preferentially Found in Known Cytotoxic T-Lymphocyte Epitopes. J. Virol., 79(17):11523-11528, Sep 2005. PubMed ID: 16103205. Show all entries for this paper.


Displaying record number 1143

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120(379-387 LAI)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Subtype B
Species (MHC/HLA) human(B*1516)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 55035

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location  
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Species (MHC/HLA) human(B*1516, Cw4)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, immunodominance, optimal epitope

Notes

References

Bihl2006 Florian Bihl, Nicole Frahm, Loriana Di Giammarino, John Sidney, Mina John, Karina Yusim, Tonia Woodberry, Kaori Sango, Hannah S. Hewitt, Leah Henry, Caitlyn H. Linde, John V. Chisholm, III, Tauheed M. Zaman, Eunice Pae, Simon Mallal, Bruce D Walker, Alessandro Sette, Bette T. Korber, David Heckerman, and Christian Brander. Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses. J. Immunol., 176(7):4094-4101, 1 Apr 2006. PubMed ID: 16547245. Show all entries for this paper.


Displaying record number 60255

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location Env(375-383)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Epitope Name SF9
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 53670

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Subtype B, C
Species (MHC/HLA) human(B63)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HLA cross-presentation, optimal epitope

Notes

References

Frahm2005a Nicole Frahm, Sharon Adams, Photini Kiepiela, Caitlyn H. Linde, Hannah S. Hewitt, Mathias Lichterfeld, Kaori Sango, Nancy V. Brown, Eunice Pae, Alysse G. Wurcel, Marcus Altfeld, Margaret E. Feeney, Todd M. Allen, Timothy Roach, M. Anne St. John, Eric S. Daar, Eric Rosenberg, Bette Korber, Francesco Marincola, Bruce D. Walker, Philip J. R. Goulder, and Christian Brander. HLA-B63 Presents HLA-B57/B58-Restricted Cytotoxic T-Lymphocyte Epitopes and Is Associated with Low Human Immunodeficiency Virus Load. J. Virol., 79(16):10218-10225, Aug 2005. PubMed ID: 16051815. Show all entries for this paper.


Displaying record number 60253

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location Env(375-383)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Epitope Name SF9
Species (MHC/HLA) human(C*04)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60254

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location Env(375-383)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Epitope Name SF9
Species (MHC/HLA) human(C*14)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 61616

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location Env
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Show epitope variants
Epitope Name Env Cw4-SF9
Subtype B
Species (MHC/HLA) human(Cw*04)
Immunogen HIV-1 infection
Patient MHC/HLA 9213: A*01, A*24, B*38, B*44, Cw*04
Country Germany, Switzerland, United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords escape, acute/early infection

Notes

References

Henn2012 Matthew R. Henn, Christian L. Boutwell, Patrick Charlebois, Niall J. Lennon, Karen A. Power, Alexander R. Macalalad, Aaron M. Berlin, Christine M. Malboeuf, Elizabeth M. Ryan, Sante Gnerre, Michael C. Zody, Rachel L. Erlich, Lisa M. Green, Andrew Berical, Yaoyu Wang, Monica Casali, Hendrik Streeck, Allyson K. Bloom, Tim Dudek, Damien Tully, Ruchi Newman, Karen L. Axten, Adrianne D. Gladden, Laura Battis, Michael Kemper, Qiandong Zeng, Terrance P. Shea, Sharvari Gujja, Carmen Zedlack, Olivier Gasser, Christian Brander, Christoph Hess, Huldrych F. Günthard, Zabrina L. Brumme, Chanson J. Brumme, Suzane Bazner, Jenna Rychert, Jake P. Tinsley, Ken H. Mayer, Eric Rosenberg, Florencia Pereyra, Joshua Z. Levin, Sarah K. Young, Heiko Jessen, Marcus Altfeld, Bruce W. Birren, Bruce D. Walker, and Todd M. Allen. Whole Genome Deep Sequencing of HIV-1 Reveals the Impact of Early Minor Variants Upon Immune Recognition During Acute Infection. PLoS Pathog., 8(3):e1002529, 2012. PubMed ID: 22412369. Show all entries for this paper.


Displaying record number 57184

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Epitope Name SF9
Species (MHC/HLA) human(Cw*04)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods Chromium-release assay, Tetramer binding
Keywords variant cross-reactivity

Notes

References

Thananchai2009 Hathairat Thananchai, Tariro Makadzange, Katsumi Maenaka, Kimiko Kuroki, Yanchun Peng, Chris Conlon, Sarah Rowland-Jones, and Tao Dong. Reciprocal Recognition of an HLA-Cw4-Restricted HIV-1 gp120 Epitope by CD8+ T Cells and NK Cells. AIDS, 23(2):189-193, 14 Jan 2009. PubMed ID: 19098488. Show all entries for this paper.


Displaying record number 61608

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location Env
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Show epitope variants
Epitope Name Cw4-SF9 Env
Species (MHC/HLA) human(Cw*04)
Immunogen HIV-1 infection
Experimental methods Other
Keywords escape

Notes

References

Pandit2014 Aridaman Pandit and Rob J. de Boer. Reliable Reconstruction of HIV-1 Whole Genome Haplotypes Reveals Clonal Interference and Genetic Hitchhiking among Immune Escape Variants. Retrovirology, 11:56, 4 Jul 2014. PubMed ID: 24996694. Show all entries for this paper.


Displaying record number 57640

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location  
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Epitope Name SF9
Subtype A, B
Species (MHC/HLA) (Cw*0401)
Immunogen HIV-1 infection
Country Kenya, United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Tetramer binding
Keywords  

Notes

References

Makadzange2010 Azure T. Makadzange, Geraldine Gillespie, Tao Dong, Peter Kiama, Job Bwayo, Joshua Kimani, Frank Plummer, Philippa Easterbrook, and Sarah L. Rowland-Jones. Characterization of an HLA-C-Restricted CTL Response in Chronic HIV Infection. Eur. J. Immunol., 40(4):1036-1041, Apr 2010. PubMed ID: 20104487. Show all entries for this paper.


Displaying record number 57927

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location Env(375-383)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(Cw*0401)
Immunogen HIV-1 infection
Patient MHC/HLA A*0101, A*0301, B*0801, B*3503, Cw*0401, Cw*0701
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Herbeck2011 Joshua T. Herbeck, Morgane Rolland, Yi Liu, Sherry McLaughlin, John McNevin, Hong Zhao, Kim Wong, Julia N. Stoddard, Dana Raugi, Stephanie Sorensen, Indira Genowati, Brian Birditt, Angela McKay, Kurt Diem, Brandon S. Maust, Wenjie Deng, Ann C. Collier, Joanne D. Stekler, M. Juliana McElrath, and James I. Mullins. Demographic Processes Affect HIV-1 Evolution in Primary Infection before the Onset of Selective Processes. J. Virol., 85(15):7523-7534, Aug 2011. PubMed ID: 21593162. Show all entries for this paper.


Displaying record number 777

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120(376-383 PV22)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Species (MHC/HLA) human(Cw*0401)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 52249

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Subtype A
Species (MHC/HLA) human(Cw*0401, Cw*0407)
Immunogen HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS), HLA cross-presentation

Notes

References

Bird2002 Thomas G. Bird, Rupert Kaul, Timothy Rostron, Joshua Kimani, Joanne Embree, Paul P. Dunn, Job J. Bwayo, Francis A. Plummer, Sarah L. Rowland-Jones, Tao Dong, and The Oxford-Nairobi HLA Collaborative Group. HLA Typing in a Kenyan Cohort Identifies Novel Class I Alleles that Restrict Cytotoxic T-Cell Responses to Local HIV-1 Clades. AIDS, 16(14):1899-1904, 27 Sep 2002. PubMed ID: 12351949. Show all entries for this paper.


Displaying record number 776

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120(376-383 PV22)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Species (MHC/HLA) human(Cw4)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Johnson1993 R. P. Johnson, A. Trocha, T. M. Buchanan, and B. D. Walker. Recognition of a Highly Conserved Region of Human Immunodeficiency Virus Type 1 gp120 by an HLA-Cw4-Restricted Cytotoxic T-Lymphocyte Clone. J. Virol., 67:438-445, 1993. The epitope sequence FNCGGEFF stimulates CTL response; the natural variants FNCRGEFF (SF2), TNCRGEFL (ROD) and LNCGGEFF (NDK) do not serve as epitopes. This was the first report of an HIV antigen specific target cells restricted by an HLA-C molecule, Cw4. PubMed ID: 7677956. Show all entries for this paper.


Displaying record number 57840

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Epitope Name SF9
Subtype B
Species (MHC/HLA) human(Cw4)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, TCR binding
Keywords rate of progression, TCR usage, optimal epitope

Notes

References

Berger2011 Christoph T. Berger, Nicole Frahm, David A. Price, Beatriz Mothe, Musie Ghebremichael, Kari L. Hartman, Leah M. Henry, Jason M. Brenchley, Laura E. Ruff, Vanessa Venturi, Florencia Pereyra, John Sidney, Alessandro Sette, Daniel C. Douek, Bruce D. Walker, Daniel E. Kaufmann, and Christian Brander. High-Functional-Avidity Cytotoxic T Lymphocyte Responses to HLA-B-Restricted Gag-Derived Epitopes Associated with Relative HIV Control. J. Virol., 85(18):9334-9345, Sep 2011. PubMed ID: 21752903. Show all entries for this paper.


Displaying record number 1697

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120(376-383)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Species (MHC/HLA) human(Cw4)
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS), immunodominance

Notes

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


Displaying record number 778

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location gp120(376-383 PV22)
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Species (MHC/HLA) human(Cw4)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Wolinsky1996 S. M. Wolinsky, B. T. M. Korber, A. U. Neumann, M. Daniels, K. J. Kuntsman, A. J. Whetsell, M. R. Furtado, Y. Chao, D. D. Ho, J. T. Safrit, and R. A. Koup. Adaptive Evolution of Human Immunodeficiency Virus-Type 1 during the Natural Course of Infection. Science, 272:537-542, 1996. In a longitudinal study of six patients, epitope variation occurred only when there was a notable CTLp frequency and the individual had the appropriate HLA type. PubMed ID: 8614801. Show all entries for this paper.


Displaying record number 54951

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location  
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection, vaccine
Patient MHC/HLA A3, A33; B15 (63), B27
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type canarypox prime with gp120 boost
Vaccine strain other
Vaccine component gp160

Notes

References

Horton2006a Helen Horton, Colin Havenar-Daughton, Deborah Lee, Erin Moore, Jianhong Cao, John McNevin, Thomas Andrus, Haiying Zhu, Abbe Rubin, Tuofu Zhu, Connie Celum, and M. Juliana McElrath. Induction of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses in HIV Vaccine Trial Participants Who Subsequently Acquire HIV-1 Infection. J. Virol., 80(19):9779-9788, Oct 2006. PubMed ID: 16973582. Show all entries for this paper.


Displaying record number 56130

HXB2 Location gp160(375-383)
gp120(375-383)
DNA(7347..7373)
gp160 Epitope Map
Author Location Env
Epitope SFNCGGEFF Epitope Alignment
SFNCGGEFF epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA A*0101, B*1567, B*8101, Cw*1402, Cw*1801
Country Kenya
Experimental methods CD8 T-cell Elispot - IFNγ, Proliferation
Keywords assay or method development

Notes

References

McKinnon2008 Lyle R. McKinnon, T. Blake Ball, Charles Wachihi, Nyakio Chinga, Anne Maingi, Ma Luo, Keith R. Fowke, and Francis A. Plummer. Substantial Intrapatient Differences in the Breadth and Specificity of HIV-Specific CD8+ T-Cell Interferon-gamma and Proliferation Responses. J. Acquir. Immune Defic. Syndr., 49(2):123-127, 1 Oct 2008. PubMed ID: 18769359. Show all entries for this paper.


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