HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 16 matching records:

Displaying record number 55942

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location gp120
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Epitope Name SY9(gp120)
Subtype B
Species (MHC/HLA) human(A29)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 52631

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location gp120(209-217)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Species (MHC/HLA) human(A29)
Immunogen HIV-1 infection
Patient MHC/HLA 1168: A*0201, A29, B44, B60, Cw16, Cw3
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords binding affinity, acute/early infection, early-expressed proteins

Notes

References

Cao2003 Jianhong Cao, John McNevin, Sarah Holte, Lisa Fink, Lawrence Corey, and M. Juliana McElrath. Comprehensive Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon-Secreting CD8+ T Cells in Primary HIV-1 Infection. J. Virol., 77(12):6867-6878, Jun 2003. PubMed ID: 12768006. Show all entries for this paper.


Displaying record number 1535

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location gp120(213-221 SF2)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Species (MHC/HLA) human(A29)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.


Displaying record number 53363

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location ( B consensus)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Epitope Name SY9
Subtype B
Species (MHC/HLA) human(A29)
Immunogen HIV-1 infection
Patient MHC/HLA A28, A29, B14, B44, Cw8
Country United States
Experimental methods Chromium-release assay, Cytokine production, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords assay or method development, memory cells, characterizing CD8+ T cells

Notes

References

Lichterfeld2004b Mathias Lichterfeld, Xu G. Yu, Michael T. Waring, Stanley K. Mui, Mary N. Johnston, Daniel Cohen, Marylyn M. Addo, John Zaunders, Galit Alter, Eunice Pae, Daryld Strick, Todd M. Allen, Eric S. Rosenberg, Bruce D. Walker, and Marcus Altfeld. HIV-1-Specific Cytotoxicity Is Preferentially Mediated by a Subset of CD8+ T Cells Producing both Interferon-gamma and Tumor Necrosis Factor-alpha. Blood, 104(2):487-394, 15 Jul 2004. PubMed ID: 15059848. Show all entries for this paper.


Displaying record number 57576

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location gp160(209-217)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Epitope Name SY9
Subtype B
Species (MHC/HLA) (A*29)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Dinges2010 Warren L. Dinges, Julia Richardt, David Friedrich, Emilie Jalbert, Yi Liu, Claire E. Stevens, Janine Maenza, Ann C. Collier, Daniel E. Geraghty, Jeremy Smith, Zoe Moodie, James I. Mullins, M. Juliana McElrath, and Helen Horton. Virus-Specific CD8+ T-Cell Responses Better Define HIV Disease Progression than HLA Genotype. J. Virol., 84(9):4461-4468, May 2010. PubMed ID: 20147397. Show all entries for this paper.


Displaying record number 60248

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location Env(209-217)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Epitope Name SY9
Species (MHC/HLA) human(A*29)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 1207

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location ( LAI)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Subtype B
Species (MHC/HLA) human(A*2902)
Immunogen  
Experimental methods  
Keywords optimal epitope

References

Altfeld2000c M. Altfeld. Personal communication, 2000. Show all entries for this paper.

Llano2019 Anuska Llano, Samandhy CedeƱo, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 53219

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location gp160(207-215 BORI, WEAU)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Show epitope variants
Epitope Name gp160 SY9
Subtype B
Species (MHC/HLA) human(A*2902)
Immunogen HIV-1 infection
Patient MHC/HLA A*2902, B*1402, Cw*0802; A*2902, B*0801, B*4403
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords dynamics, immunodominance, escape, acute/early infection, characterizing CD8+ T cells, viral fitness and reversion

Notes

References

Jones2004 Nicola A. Jones, Xiping Wei, Darren R. Flower, MaiLee Wong, Franziska Michor, Michael S. Saag, Beatrice H. Hahn, Martin A. Nowak, George M. Shaw, and Persephone Borrow. Determinants of Human Immunodeficiency Virus Type 1 Escape from the Primary CD8+ Cytotoxic T Lymphocyte Response. J. Exp. Med., 200(10):1243-1256, 15 Nov 2004. PubMed ID: 15545352. Show all entries for this paper.


Displaying record number 61006

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location gp160(209-217)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Subtype B
Species (MHC/HLA) human(A*2902)
Immunogen HIV-1 infection
Patient MHC/HLA 11439: A*0101, A*2902, B*3801, B*4403, Cw*1203, Cw*1601; 41325: A*2902, A*3201, B*3501, B*4403, Cw*0401, Cw*1601
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 60251

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location Env(209-217)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Epitope Name SY9
Species (MHC/HLA) human(B*14)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60252

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location Env(209-217)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Epitope Name SY9
Species (MHC/HLA) human(B*5801)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60250

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location Env(209-217)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Epitope Name SY9
Species (MHC/HLA) human(B*82)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60249

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location Env(209-217)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Epitope Name SY9
Species (MHC/HLA) human(C*18)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 55320

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location Env
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Subtype B, D
Species (MHC/HLA) human, mouse
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Cytokine production
Keywords subtype comparisons, epitope processing, optimal epitope

Notes

References

Zhan2007 Xiaoyan Zhan, Julia L. Hurwitz, Scott A. Brown, and Karen S. Slobod. HIV-1 Envelope T Cell Epitope ``Hotspots'' among Mice and Humans and among CD4+ and CD8+ T Cell Subpopulations. AIDS Res. Hum. Retroviruses, 23(3):471-476, Mar 2007. PubMed ID: 17411381. Show all entries for this paper.


Displaying record number 54687

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location gp160(209-217)
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA A*2902, B*1402; A*2902, B*0801, B*4403
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords HAART, ART, escape, viral fitness and reversion

Notes

References

Asquith2006 Becca Asquith, Charles T. T. Edwards, Marc Lipsitch, and Angela R. McLean. Inefficient Cytotoxic T Lymphocyte-Mediated Killing of HIV-1-Infected Cells In Vivo. PLoS Biol., 4(4):e90, Apr 2006. PubMed ID: 16515366. Show all entries for this paper.


Displaying record number 56210

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location gp160
Epitope SFEPIPIHY Epitope Alignment
SFEPIPIHY epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection, in vitro stimulation or selection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Garrison2007 Keith E. Garrison, R. Brad Jones, Duncan A. Meiklejohn, Naveed Anwar, Lishomwa C. Ndhlovu, Joan M. Chapman, Ann L. Erickson, Ashish Agrawal, Gerald Spotts, Frederick M. Hecht, Seth Rakoff-Nahoum, Jack Lenz, Mario A. Ostrowski, and Douglas F. Nixon. T Cell Responses to Human Endogenous Retroviruses in HIV-1 Infection. PLoS Pathog., 3(11):e165, Nov 2007. PubMed ID: 17997601. Show all entries for this paper.


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