HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 53955

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HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location ( C consensus)
Epitope SFDPIPIHY Epitope Alignment
SFDPIPIHY epitope logo
Subtype C
Species (MHC/HLA) human(A*29)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 62240

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HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location Env(206-217)
Epitope SFDPIPIHY Epitope Alignment
SFDPIPIHY epitope logo
Show epitope variants
Epitope Name Env-SY9
Subtype C
Species (MHC/HLA) human(A*29)
Immunogen HIV-1 infection
Patient MHC/HLA 021-C: A*02:05, A*29:02, B*42:01, B*44:03, C*02:10, C*17:01; 021-M: A*02:05, A*33:01, B*42:01, B*44:03, C*02:10, C*17:01
Country South Africa, United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords dynamics, responses in children, mother-to-infant transmission, rate of progression, escape

Notes

References

Leitman2017 Ellen M. Leitman, Christina F. Thobakgale, Emily Adland, M. Azim Ansari, Jayna Raghwani, Andrew J. Prendergast, Gareth Tudor-Williams, Photini Kiepiela, Joris Hemelaar, Jacqui Brener, Ming-Han Tsai, Masahiko Mori, Lynn Riddell, Graz Luzzi, Pieter Jooste, Thumbi Ndung'u, Bruce D. Walker, Oliver G. Pybus, Paul Kellam, Vivek Naranbhai, Philippa C. Matthews, Astrid Gall, and Philip J. R. Goulder. Role of HIV-Specific CD8+ T Cells in Pediatric HIV Cure Strategies after Widespread Early Viral Escape. J. Exp. Med., 214(11):3239-3261, 6 Nov 2017. PubMed ID: 28983013. Show all entries for this paper.


Displaying record number 53282

Download this epitope record as JSON.

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location ( C consensus)
Epitope SFDPIPIHY Epitope Alignment
SFDPIPIHY epitope logo
Subtype C
Species (MHC/HLA) human(A29)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords characterizing CD8+ T cells

Notes

References

Kiepiela2004 Photini Kiepiela, Alasdair J. Leslie, Isobella Honeyborne, Danni Ramduth, Christina Thobakgale, Senica Chetty, Prinisha Rathnavalu, Corey Moore, Katja J. Pfafferott, Louise Hilton, Peter Zimbwa, Sarah Moore, Todd Allen, Christian Brander, Marylyn M. Addo, Marcus Altfeld, Ian James, Simon Mallal, Michael Bunce, Linda D. Barber, James Szinger, Cheryl Day, Paul Klenerman, James Mullins, Bette Korber, Hoosen M. Coovadia, Bruce D. Walker, and Philip J. R. Goulder. Dominant Influence of HLA-B in Mediating the Potential Co-Evolution of HIV and HLA. Nature, 432(7018):769-775, 9 Dec 2004. LA-UR 04-5920. PubMed ID: 15592417. Show all entries for this paper.


Displaying record number 56261

Download this epitope record as JSON.

HXB2 Location gp160(209-217)
gp120(209-217)
DNA(6849..6875)
gp160 Epitope Map
Author Location  
Epitope SFDPIPIHY Epitope Alignment
SFDPIPIHY epitope logo
Subtype C
Species (MHC/HLA) human(A29)
Immunogen HIV-1 infection
Patient MHC/HLA A*23:01, A*29:02, B*41:01, B*42:01, C*17:01
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords rate of progression

Notes

References

Gray2009 Clive M. Gray, Mandla Mlotshwa, Catherine Riou, Tiyani Mathebula, Debra de Assis Rosa, Tumelo Mashishi, Cathal Seoighe, Nobubelo Ngandu, Francois van Loggerenberg, Lynn Morris, Koleka Mlisana, Carolyn Williamson, Salim Abdool Karim, and CAPRISA 002 Acute Infection Study Team. Human Immunodeficiency Virus-Specific gamma Interferon Enzyme-Linked Immunospot Assay Responses Targeting Specific Regions of the Proteome during Primary Subtype C Infection Are Poor Predictors of the Course of Viremia and Set Point. J. Virol., 83(1):470-478, Jan 2009. PubMed ID: 18945774. Show all entries for this paper.


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