HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 56504

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HXB2 Location Pol(838-847)
Integrase(123-132)
DNA(4596..4625)
Pol Epitope Map
Author Location Integrase
Epitope SAAVKAACWW Epitope Alignment
SAAVKAACWW epitope logo
Subtype C
Species (MHC/HLA) human(B*58:01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords viral fitness and reversion, HLA associated polymorphism

Notes

References

Matthews2008 Philippa C. Matthews, Andrew Prendergast, Alasdair Leslie, Hayley Crawford, Rebecca Payne, Christine Rousseau, Morgane Rolland, Isobella Honeyborne, Jonathan Carlson, Carl Kadie, Christian Brander, Karen Bishop, Nonkululeko Mlotshwa, James I. Mullins, Hoosen Coovadia, Thumbi Ndung'u, Bruce D. Walker, David Heckerman, and Philip J. R. Goulder. Central Role of Reverting Mutations in HLA Associations with Human Immunodeficiency Virus Set Point. J. Virol., 82(17):8548-8559, Sep 2008. PubMed ID: 18596105. Show all entries for this paper.


Displaying record number 57896

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HXB2 Location Pol(838-847)
Integrase(123-132)
DNA(4596..4625)
Pol Epitope Map
Author Location Integrase
Epitope SAAVKAACWW Epitope Alignment
SAAVKAACWW epitope logo
Subtype C
Species (MHC/HLA) human(B*58:01)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, acute/early infection

Notes

References

Chopera2011 D. R. Chopera, M. Mlotshwa, Z. Woodman, K. Mlisana, D. de Assis Rosa, D. P. Martin, S. Abdool Karim, C. M. Gray, C. Williamson, and CAPRISA 002 Study Team. Virological and Immunological Factors Associated with HIV-1 Differential Disease Progression in HLA-B*58:01-Positive Individuals. J. Virol., 85(14):7070-7080, Jul 2011. PubMed ID: 21613398. Show all entries for this paper.


Displaying record number 57904

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HXB2 Location Pol(838-847)
Integrase(123-132)
DNA(4596..4625)
Pol Epitope Map
Author Location Integrase
Epitope SAAVKAACWW Epitope Alignment
SAAVKAACWW epitope logo
Subtype C
Species (MHC/HLA) human(B*58:01)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, acute/early infection

Notes

References

Chopera2011 D. R. Chopera, M. Mlotshwa, Z. Woodman, K. Mlisana, D. de Assis Rosa, D. P. Martin, S. Abdool Karim, C. M. Gray, C. Williamson, and CAPRISA 002 Study Team. Virological and Immunological Factors Associated with HIV-1 Differential Disease Progression in HLA-B*58:01-Positive Individuals. J. Virol., 85(14):7070-7080, Jul 2011. PubMed ID: 21613398. Show all entries for this paper.


Displaying record number 61626

Download this epitope record as JSON.

HXB2 Location Pol(838-847)
Integrase(123-132)
DNA(4596..4625)
Pol Epitope Map
Author Location Integrase
Epitope SAAVKAACWW Epitope Alignment
SAAVKAACWW epitope logo
Epitope Name B*57-SW10
Subtype C
Species (MHC/HLA) human(B*58:01)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords elite controllers

Notes

References

Koofhethile2016 Catherine K. Koofhethile, Zaza M. Ndhlovu, Christina Thobakgale-Tshabalala, Julia G. Prado, Nasreen Ismail, Zenele Mncube, Lungile Mkhize, Mary van der Stok, Nonhlanhla Yende, Bruce D. Walker, Philip J. R. Goulder, and Thumbi Ndung'u. CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles. J. Virol., 90(15):6818-6831, 1 Aug 2016. PubMed ID: 27194762. Show all entries for this paper.


Displaying record number 62883

Download this epitope record as JSON.

HXB2 Location Pol(838-847)
Integrase(123-132)
Pol Epitope Map
Author Location Integrase(123-132)
Epitope SAAVKAACWW Epitope Alignment
SAAVKAACWW epitope logo
Show epitope variants
Subtype B, C
Species (MHC/HLA) human
Immunogen HIV-1 infection, engineered
Experimental methods Other, Relative replication capacity assay
Keywords vaccine antigen design

Notes

References

Ojwach2021 Doty B. A. Ojwach, Paradise Madlala, Michelle Gordon, Thumbi Ndung'u, and Jaclyn K. Mann. Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design. Virology, 554:1-8 doi, Feb 2021. PubMed ID: 33316731 Show all entries for this paper.


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