HIV molecular immunology database
Found 6 matching records:
Download this epitope record as JSON.
HXB2 Location | Gag(263-272) p24(131-140) DNA(1576..1605) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(263-272) | |
Epitope |
RRWIQLGLQK
|
Epitope Alignment
|
Epitope Name | RK10 | |
Species (MHC/HLA) | human(B*18) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(263-272) p24(131-140) DNA(1576..1605) |
Gag Epitope Map |
---|---|---|
Author Location | p24(260-299) | |
Epitope |
RRWIQLGLQK
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*27) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | rate of progression, acute/early infection |
Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(263-272) p24(131-140) DNA(1576..1605) |
Gag Epitope Map |
---|---|---|
Author Location | p24(260-269 HIV-2) | |
Epitope |
RRWIQLGLQK
|
Epitope Alignment
|
Species (MHC/HLA) | human(B27) | |
Immunogen | ||
Experimental methods | ||
Keywords |
Brander1996 Christian Brander and Bruce Walker. The HLA-Class I Restricted CTL Response in HIV-1 Infection: Systematic Identification of Optimal Epitopes. In The HLA-Class I Restricted CTL Response in HIV-1 Infection: Systematic Identification of Optimal Epitopes. pages IV--50--IV--60. Los Alamos National Laboratory, Theoretical Biology and Biophysics, Los Alamos, New Mexico, 1996. URL: http://hiv-web.lanl.gov/immunology. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(263-272) p24(131-140) DNA(1576..1605) |
Gag Epitope Map |
---|---|---|
Author Location | p24(260-269 HIV-2) | |
Epitope |
RRWIQLGLQK
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*27:03) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(263-272) p24(131-140) DNA(1576..1605) |
Gag Epitope Map |
---|---|---|
Author Location | p24 | |
Epitope |
RRWIQLGLQK
|
Epitope Alignment
|
Species (MHC/HLA) | human, macaque(B*27:05) | |
Immunogen | peptide-HLA interaction | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | binding affinity |
Loffredo2009 John T. Loffredo, John Sidney, Alex T. Bean, Dominic R. Beal, Wilfried Bardet, Angela Wahl, Oriana E. Hawkins, Shari Piaskowski, Nancy A. Wilson, William H. Hildebrand, David I. Watkins, and Alessandro Sette. Two MHC Class I Molecules Associated with Elite Control of Immunodeficiency Virus Replication, Mamu-B*08 and HLA-B*2705, Bind Peptides with Sequence Similarity. J. Immunol., 182(12):7763-7775, 15 Jun 2009. PubMed ID: 19494300. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(263-272) p24(131-140) DNA(1576..1605) |
Gag Epitope Map |
---|---|---|
Author Location | p24(263-272) | |
Epitope |
RRWIQLGLQK
|
Epitope Alignment
|
Show epitope variants | ||
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | assay or method development, protective allele |
Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.