HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 13 matching records:

Displaying record number 58542

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location gp41
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Epitope Name A1-RY9
Subtype B
Species (MHC/HLA) human(A*01)
Immunogen HIV-1 infection
Country United States
Experimental methods  
Keywords review, rate of progression, acute/early infection

Notes

References

Streeck2010 Hendrik Streeck and Douglas F. Nixon. T Cell Immunity in Acute HIV-1 Infection. J. Infect. Dis., 202(Suppl 2):S302-8, 15 Oct 2010. PubMed ID: 20846037. Show all entries for this paper.


Displaying record number 59308

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location gp41
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Epitope Name RY9
Species (MHC/HLA) human(A*01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression

Notes

References

Streeck2014 Hendrik Streeck, Richard Lu, Noor Beckwith, Mark Milazzo, Michelle Liu, Jean-Pierre Routy, Susan Little, Heiko Jessen, Anthony D. Kelleher, Frederick Hecht, Rafick-Pierre Sekaly, Galit Alter, David Heckerman, Mary Carrington, Eric S. Rosenberg, and Marcus Altfeld. Emergence of Individual HIV-Specific CD8 T Cell Responses during Primary HIV-1 Infection Can Determine Long-Term Disease Outcome. J. Virol., 88(21):12793-12801, Nov 2014. PubMed ID: 25165102. Show all entries for this paper.


Displaying record number 52521

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location gp160(787-795)
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Species (MHC/HLA) human(A*0101)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

References

Llano2019 Anuska Llano, Samandhy CedeƱo, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 57090

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location gp41(276-284 DU422)
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Subtype B
Species (MHC/HLA) human(A*0101)
Immunogen in vitro stimulation or selection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Tetramer binding
Keywords dendritic cells

Notes

References

Colleton2009 Bonnie A. Colleton, Xiao-Li Huang, Nada M. Melhem, Zheng Fan, Luann Borowski, Giovanna Rappocciolo, and Charles R. Rinaldo. Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells. J. Virol., 83(12):6288-6299, Jun 2009. PubMed ID: 19357176. Show all entries for this paper.


Displaying record number 61000

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location gp160(787-795)
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Subtype B
Species (MHC/HLA) human(A*0101)
Immunogen HIV-1 infection
Patient MHC/HLA 71101: A*0101, A*0301, B*0801, B*3503, Cw*0401, Cw*0701
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 56460

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location gp41
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Epitope Name RY9(gp41)
Subtype B
Species (MHC/HLA) human(A1)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords non-susceptible form

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 57928

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location Env(787-795)
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(A1)
Immunogen HIV-1 infection
Patient MHC/HLA A*0101, A*0301, B*0801, B*3503, Cw*0401, Cw*0701
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Herbeck2011 Joshua T. Herbeck, Morgane Rolland, Yi Liu, Sherry McLaughlin, John McNevin, Hong Zhao, Kim Wong, Julia N. Stoddard, Dana Raugi, Stephanie Sorensen, Indira Genowati, Brian Birditt, Angela McKay, Kurt Diem, Brandon S. Maust, Wenjie Deng, Ann C. Collier, Joanne D. Stekler, M. Juliana McElrath, and James I. Mullins. Demographic Processes Affect HIV-1 Evolution in Primary Infection before the Onset of Selective Processes. J. Virol., 85(15):7523-7534, Aug 2011. PubMed ID: 21593162. Show all entries for this paper.


Displaying record number 54219

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location gp41
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Epitope Name A1-RY9(gp41)
Species (MHC/HLA) human(A1)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 52637

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location gp41(787-795)
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Species (MHC/HLA) human(A1)
Immunogen HIV-1 infection
Patient MHC/HLA A1, A1, B14, B8, Cw7, Cw8
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords binding affinity, acute/early infection, early-expressed proteins

Notes

References

Cao2003 Jianhong Cao, John McNevin, Sarah Holte, Lisa Fink, Lawrence Corey, and M. Juliana McElrath. Comprehensive Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon-Secreting CD8+ T Cells in Primary HIV-1 Infection. J. Virol., 77(12):6867-6878, Jun 2003. PubMed ID: 12768006. Show all entries for this paper.


Displaying record number 60203

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location Env(787-795)
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Epitope Name RY9
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60201

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location Env(787-795)
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Epitope Name RY9
Species (MHC/HLA) human(C*02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60202

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location Env(787-795)
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Epitope Name RY9
Species (MHC/HLA) human(C*14)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54935

HXB2 Location gp160(787-795)
gp41(276-284)
DNA(8583..8609)
gp160 Epitope Map
Author Location  
Epitope RRGWEVLKY Epitope Alignment
RRGWEVLKY epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection, vaccine
Patient MHC/HLA A1, A2; B38, B8
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type canarypox
Vaccine strain B clade LAI, B clade MN
Vaccine component Gag-Pol, gp120, gp41

Notes

References

Horton2006a Helen Horton, Colin Havenar-Daughton, Deborah Lee, Erin Moore, Jianhong Cao, John McNevin, Thomas Andrus, Haiying Zhu, Abbe Rubin, Tuofu Zhu, Connie Celum, and M. Juliana McElrath. Induction of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses in HIV Vaccine Trial Participants Who Subsequently Acquire HIV-1 Infection. J. Virol., 80(19):9779-9788, Oct 2006. PubMed ID: 16973582. Show all entries for this paper.


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