HIV molecular immunology database
Found 13 matching records:
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | gp41 | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Epitope Name | A1-RY9 | |
Subtype | B | |
Species (MHC/HLA) | human(A*01) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | ||
Keywords | review, rate of progression, acute/early infection |
Streeck2010 Hendrik Streeck and Douglas F. Nixon. T Cell Immunity in Acute HIV-1 Infection. J. Infect. Dis., 202(Suppl 2):S302-8, 15 Oct 2010. PubMed ID: 20846037. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | gp41 | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Epitope Name | RY9 | |
Species (MHC/HLA) | human(A*01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression |
Streeck2014 Hendrik Streeck, Richard Lu, Noor Beckwith, Mark Milazzo, Michelle Liu, Jean-Pierre Routy, Susan Little, Heiko Jessen, Anthony D. Kelleher, Frederick Hecht, Rafick-Pierre Sekaly, Galit Alter, David Heckerman, Mary Carrington, Eric S. Rosenberg, and Marcus Altfeld. Emergence of Individual HIV-Specific CD8 T Cell Responses during Primary HIV-1 Infection Can Determine Long-Term Disease Outcome. J. Virol., 88(21):12793-12801, Nov 2014. PubMed ID: 25165102. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | gp160(787-795) | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Species (MHC/HLA) | human(A*01:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | gp41(276-284 DU422) | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(A*01:01) | |
Immunogen | in vitro stimulation or selection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay, Tetramer binding | |
Keywords | dendritic cells |
Colleton2009 Bonnie A. Colleton, Xiao-Li Huang, Nada M. Melhem, Zheng Fan, Luann Borowski, Giovanna Rappocciolo, and Charles R. Rinaldo. Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells. J. Virol., 83(12):6288-6299, Jun 2009. PubMed ID: 19357176. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | gp160(787-795) | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(A*01:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | 71101: A*01:01, A*03:01, B*08:01, B*35:03, C*04:01, C*07:01 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | acute/early infection |
Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | gp41 | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Epitope Name | RY9(gp41) | |
Subtype | B | |
Species (MHC/HLA) | human(A1) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | non-susceptible form, chronic infection |
Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(787-795) | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Show epitope variants | ||
Subtype | B | |
Species (MHC/HLA) | human(A1) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*01:01, A*03:01, B*08:01, B*35:03, C*04:01, C*07:01 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | acute/early infection |
Herbeck2011 Joshua T. Herbeck, Morgane Rolland, Yi Liu, Sherry McLaughlin, John McNevin, Hong Zhao, Kim Wong, Julia N. Stoddard, Dana Raugi, Stephanie Sorensen, Indira Genowati, Brian Birditt, Angela McKay, Kurt Diem, Brandon S. Maust, Wenjie Deng, Ann C. Collier, Joanne D. Stekler, M. Juliana McElrath, and James I. Mullins. Demographic Processes Affect HIV-1 Evolution in Primary Infection before the Onset of Selective Processes. J. Virol., 85(15):7523-7534, Aug 2011. PubMed ID: 21593162. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | gp41 | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Epitope Name | A1-RY9(gp41) | |
Species (MHC/HLA) | human(A1) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, immunodominance, early-expressed proteins |
Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | gp41(787-795) | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Species (MHC/HLA) | human(A1) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A1, A1, B14, B8, Cw7, Cw8 | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | binding affinity, acute/early infection, early-expressed proteins |
Cao2003 Jianhong Cao, John McNevin, Sarah Holte, Lisa Fink, Lawrence Corey, and M. Juliana McElrath. Comprehensive Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon-Secreting CD8+ T Cells in Primary HIV-1 Infection. J. Virol., 77(12):6867-6878, Jun 2003. PubMed ID: 12768006. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(787-795) | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Epitope Name | RY9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(787-795) | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Epitope Name | RY9 | |
Species (MHC/HLA) | human(C*02) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(787-795) | |
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Epitope Name | RY9 | |
Species (MHC/HLA) | human(C*14) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(787-795) gp41(276-284) DNA(8583..8609) |
gp160 Epitope Map |
---|---|---|
Author Location | ||
Epitope |
RRGWEVLKY
|
Epitope Alignment
|
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection, vaccine | |
Patient MHC/HLA | 014A-009: A*01, A*02, B*08, B*38, C*04, C*06 | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | vaccine-induced immune responses, acute/early infection |
Vaccine type | canarypox |
---|---|
Vaccine strain | B clade LAI, B clade MN |
Vaccine component | Gag-Pol, gp120, gp41 |
Horton2006a Helen Horton, Colin Havenar-Daughton, Deborah Lee, Erin Moore, Jianhong Cao, John McNevin, Thomas Andrus, Haiying Zhu, Abbe Rubin, Tuofu Zhu, Connie Celum, and M. Juliana McElrath. Induction of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses in HIV Vaccine Trial Participants Who Subsequently Acquire HIV-1 Infection. J. Virol., 80(19):9779-9788, Oct 2006. PubMed ID: 16973582. Show all entries for this paper.