HIV molecular immunology database
Found 7 matching records:
Download this epitope record as JSON.
HXB2 Location | Pol(113-122) Protease(57-66) DNA(2421..2450) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(113-122) | |
Epitope |
RQYDQILIEI
|
Epitope Alignment
|
Epitope Name | RI10 | |
Species (MHC/HLA) | human(A*11) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(113-122) Protease(57-66) DNA(2421..2450) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(113-122) | |
Epitope |
RQYDQILIEI
|
Epitope Alignment
|
Epitope Name | RI10 | |
Species (MHC/HLA) | human(A*32) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(113-122) Protease(57-66) DNA(2421..2450) |
Pol Epitope Map |
---|---|---|
Author Location | Protease(57-66) | |
Epitope |
RQYDQILIEI
|
Epitope Alignment
|
Epitope Name | RI10 | |
Subtype | B | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | HIV-1 infection | |
Country | Australia, Canada, Germany, United States | |
Experimental methods | ||
Keywords | escape, HLA associated polymorphism |
Brumme2008 Zabrina L. Brumme, Chanson J. Brumme, Jonathan Carlson, Hendrik Streeck, Mina John, Quentin Eichbaum, Brian L Block, Brett Baker, Carl Kadie, Martin Markowitz, Heiko Jessen, Anthony D. Kelleher, Eric Rosenberg, John Kaldor, Yuko Yuki, Mary Carrington, Todd M. Allen, Simon Mallal, Marcus Altfeld, David Heckerman, and Bruce D. Walker. Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection. J. Virol., 82(18):9216-9227, Sep 2008. PubMed ID: 18614631. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(113-122) Protease(57-66) DNA(2421..2450) |
Pol Epitope Map |
---|---|---|
Author Location | ||
Epitope |
RQYDQILIEI
|
Epitope Alignment
|
Epitope Name | RI10 | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(113-122) Protease(57-66) DNA(2421..2450) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(113-122) | |
Epitope |
RQYDQILIEI
|
Epitope Alignment
|
Epitope Name | RI10 | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(113-122) Protease(57-66) DNA(2421..2450) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(113-122) | |
Epitope |
RQYDQILIEI
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*03:01, A*30:01, B*13:01, B*14:02, C*06:02, C*08:02 | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining | |
Keywords | epitope processing, escape, mutation acquisition, viral fitness and reversion, HLA associated polymorphism |
Honeyborne2007 Isobella Honeyborne, Andrew Prendergast, Florencia Pereyra, Alasdair Leslie, Hayley Crawford, Rebecca Payne, Shabashini Reddy, Karen Bishop, Eshia Moodley, Kriebashnie Nair, Mary van der Stok, Noel McCarthy, Christine M. Rousseau, Marylyn Addo, James I. Mullins, Christian Brander, Photini Kiepiela, Bruce D. Walker, and Philip J. R. Goulder. Control of Human Immunodeficiency Virus Type 1 Is Associated with HLA-B*13 and Targeting of Multiple Gag-Specific CD8+ T-Cell Epitopes. J. Virol., 81(7):3667-3672, Apr 2007. PubMed ID: 17251285. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(113-122) Protease(57-66) DNA(2421..2450) |
Pol Epitope Map |
---|---|---|
Author Location | Protease(57-66) | |
Epitope |
RQYDQILIEI
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | RI10 | |
Subtype | B | |
Species (MHC/HLA) | human(B*13:02) | |
Immunogen | HIV-1 infection | |
Experimental methods | Relative replication capacity assay | |
Keywords | class I down-regulation by Nef, escape, novel epitope |
Shahid2015 Aniqa Shahid, Alex Olvera, Gursev Anmole, Xiaomei T. Kuang, Laura A. Cotton, Montserrat Plana, Christian Brander, Mark A. Brockman, and Zabrina L. Brumme. Consequences of HLA-B*13-Associated Escape Mutations on HIV-1 Replication and Nef Function. J. Virol., 89(22):11557-11571, Nov 2015. PubMed ID: 26355081. Show all entries for this paper.