HIV molecular immunology database
Found 5 matching records:
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWV
|
Epitope Alignment
|
Subtype | B, C | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*03:01, A*30:01, B*13:01, B*14:02, C*06:02, C*08:02 | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining | |
Keywords | epitope processing, escape, mutation acquisition, viral fitness and reversion, HLA associated polymorphism |
Honeyborne2007 Isobella Honeyborne, Andrew Prendergast, Florencia Pereyra, Alasdair Leslie, Hayley Crawford, Rebecca Payne, Shabashini Reddy, Karen Bishop, Eshia Moodley, Kriebashnie Nair, Mary van der Stok, Noel McCarthy, Christine M. Rousseau, Marylyn Addo, James I. Mullins, Christian Brander, Photini Kiepiela, Bruce D. Walker, and Philip J. R. Goulder. Control of Human Immunodeficiency Virus Type 1 Is Associated with HLA-B*13 and Targeting of Multiple Gag-Specific CD8+ T-Cell Epitopes. J. Virol., 81(7):3667-3672, Apr 2007. PubMed ID: 17251285. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWV
|
Epitope Alignment
|
Epitope Name | RV9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | HIV-1 infection | |
Country | Australia, Canada, Germany, United States | |
Experimental methods | ||
Keywords | HLA associated polymorphism |
Brumme2008 Zabrina L. Brumme, Chanson J. Brumme, Jonathan Carlson, Hendrik Streeck, Mina John, Quentin Eichbaum, Brian L Block, Brett Baker, Carl Kadie, Martin Markowitz, Heiko Jessen, Anthony D. Kelleher, Eric Rosenberg, John Kaldor, Yuko Yuki, Mary Carrington, Todd M. Allen, Simon Mallal, Marcus Altfeld, David Heckerman, and Bruce D. Walker. Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection. J. Virol., 82(18):9216-9227, Sep 2008. PubMed ID: 18614631. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | ||
Epitope |
RQDILDLWV
|
Epitope Alignment
|
Epitope Name | RV9 | |
Subtype | C | |
Species (MHC/HLA) | human(B*13:02) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay | |
Keywords | rate of progression |
Gray2009 Clive M. Gray, Mandla Mlotshwa, Catherine Riou, Tiyani Mathebula, Debra de Assis Rosa, Tumelo Mashishi, Cathal Seoighe, Nobubelo Ngandu, Francois van Loggerenberg, Lynn Morris, Koleka Mlisana, Carolyn Williamson, Salim Abdool Karim, and CAPRISA 002 Acute Infection Study Team. Human Immunodeficiency Virus-Specific gamma Interferon Enzyme-Linked Immunospot Assay Responses Targeting Specific Regions of the Proteome during Primary Subtype C Infection Are Poor Predictors of the Course of Viremia and Set Point. J. Virol., 83(1):470-478, Jan 2009. PubMed ID: 18945774. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | ||
Epitope |
RQDILDLWV
|
Epitope Alignment
|
Epitope Name | RV9 | |
Species (MHC/HLA) | human(B*13:02) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef | |
Epitope |
RQDILDLWV
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | RV9(Nef) | |
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | variant cross-reactivity, chronic infection |
Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.