HIV molecular immunology database
Found 11 matching records:
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Epitope Name | RI9 | |
Subtype | B | |
Species (MHC/HLA) | (B*13) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | acute/early infection |
Dinges2010 Warren L. Dinges, Julia Richardt, David Friedrich, Emilie Jalbert, Yi Liu, Claire E. Stevens, Janine Maenza, Ann C. Collier, Daniel E. Geraghty, Jeremy Smith, Zoe Moodie, James I. Mullins, M. Juliana McElrath, and Helen Horton. Virus-Specific CD8+ T-Cell Responses Better Define HIV Disease Progression than HLA Genotype. J. Virol., 84(9):4461-4468, May 2010. PubMed ID: 20147397. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*13) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Epitope Name | RI9 | |
Species (MHC/HLA) | human(B*13) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | RI9 | |
Species (MHC/HLA) | human(B13) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, escape, variant cross-reactivity, optimal epitope |
Harrer2005b Ellen G. Harrer, Silke Bergmann, Kathrin Eismann, Marion Rittmaier, Andreas Goldwich, Sandra M. Müller, Bernd M. Spriewald, and Thomas Harrer. A Conserved HLA B13-Restricted Cytotoxic T Lymphocyte Epitope in Nef is a Dominant Epitope in HLA B13-Positive HIV-1-Infected Patients. AIDS, 19(7):734-735, 29 Apr 2005. PubMed ID: 15821402. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | RI9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*13:02) | |
Immunogen | HIV-1 infection | |
Experimental methods | Relative replication capacity assay | |
Keywords | class I down-regulation by Nef, escape, novel epitope |
Shahid2015 Aniqa Shahid, Alex Olvera, Gursev Anmole, Xiaomei T. Kuang, Laura A. Cotton, Montserrat Plana, Christian Brander, Mark A. Brockman, and Zabrina L. Brumme. Consequences of HLA-B*13-Associated Escape Mutations on HIV-1 Replication and Nef Function. J. Virol., 89(22):11557-11571, Nov 2015. PubMed ID: 26355081. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Epitope Name | RI9 | |
Species (MHC/HLA) | human(B*15:24) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Epitope Name | RI9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114 SF2, HXBc2/Bal R5) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Show epitope variants | ||
Subtype | B | |
Species (MHC/HLA) | human(B7) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A24, A25, B18, B7, C*12, Cw7 | |
Country | United States | |
Experimental methods | Cytokine production, Degranulation, CD107a and b cell surface mobilization, Flow cytometric T-cell cytokine assay | |
Keywords | supervised treatment interruptions (STI), immunodominance, variant cross-reactivity, characterizing CD8+ T cells, drug resistance |
Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Epitope Name | RI9 | |
Species (MHC/HLA) | human(C*01) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Epitope Name | RI9 | |
Species (MHC/HLA) | human(C*15) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Nef(106-114) DNA(9112..9138) |
Nef Epitope Map |
---|---|---|
Author Location | Nef(106-114) | |
Epitope |
RQDILDLWI
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Country | India | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | subtype comparisons, computational epitope prediction, immunodominance |
Thakar2005 Madhuri R. Thakar, Leena S. Bhonge, Samir K. Lakhashe, U. Shankarkumar, Suvarna S. Sane, Smita S. Kulkarni, Bharati A. Mahajan, and Ramesh S. Paranjape. Cytolytic T Lymphocytes (CTLs) from HIV-1 Subtype C-Infected Indian Patients Recognize CTL Epitopes From a Conserved Immunodominant Region of HIV-1 Gag and Nef. J. Infect. Dis., 192(5):749-759, 1 Sep 2005. PubMed ID: 16088824. Show all entries for this paper.