HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 59012

HXB2 Location Gag(22-30)
p17(22-30)
DNA(853..879)
Gag Epitope Map
Author Location Gag(22-30)
Epitope RPGGKKHYM Epitope Alignment
RPGGKKHYM epitope logo
Show epitope variants
Epitope Name RM9-p17
Subtype C
Species (MHC/HLA) human(B*0702)
Immunogen HIV-1 infection
Patient MHC/HLA R045: B*0702; H034: A*2902, A*6802, B*0702, B*4403, Cw*0401, Cw*0702
Country Japan, South Africa, United Kingdom, United States
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, subtype comparisons, optimal epitope, novel epitope

Notes

References

Kloverpris2014 Henrik N. Kløverpris, Emily Adland, Madoka Koyanagi, Anette Stryhn, Mikkel Harndahl, Philippa C. Matthews, Roger Shapiro, Bruce D. Walker, Thumbi Ndung'u, Christian Brander, Masafumi Takiguchi, Søren Buus, and Philip Goulder. HIV Subtype Influences HLA-B*07:02-Associated HIV Disease Outcome. AIDS Res. Hum. Retroviruses, 30(5):468-475, May 2014. PubMed ID: 24010680. Show all entries for this paper.


Displaying record number 61771

HXB2 Location Gag(22-30)
p17(22-30)
DNA(853..879)
Gag Epitope Map
Author Location p17(22-30)
Epitope RPGGKKHYM Epitope Alignment
RPGGKKHYM epitope logo
Epitope Name RM9
Species (MHC/HLA) human(B*0702)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 61204

HXB2 Location Gag(22-30)
p17(22-30)
DNA(853..879)
Gag Epitope Map
Author Location Gag
Epitope RPGGKKHYM Epitope Alignment
RPGGKKHYM epitope logo
Show epitope variants
Epitope Name RM9
Subtype B
Species (MHC/HLA) human(B*0702, B*4201)
Immunogen HIV-1 infection
Experimental methods Other
Keywords review, escape, HLA associated polymorphism

Notes

References

Kloverpris2015a Henrik N. Kløverpris, Alasdair Leslie, and Philip Goulder. Role of HLA Adaptation in HIV Evolution. Front. Immunol., 6:665, 18 Jan 2016. PubMed ID: 26834742. Show all entries for this paper.


Displaying record number 59159

HXB2 Location Gag(22-30)
p17(22-30)
DNA(853..879)
Gag Epitope Map
Author Location Gag(22-30)
Epitope RPGGKKHYM Epitope Alignment
RPGGKKHYM epitope logo
Epitope Name RM9-p17
Subtype C
Species (MHC/HLA) human(B*4201)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Tetramer binding
Keywords TCR usage, characterizing CD8+ T cells

Notes

References

Kloverpris2014a Henrik N. Kløverpris, Reuben McGregor, James E McLaren, Kristin Ladell, Anette Stryhn, Catherine Koofhethile, Jacqui Brener, Fabian Chen, Lynn Riddell, Luzzi Graziano, Paul Klenerman, Alasdair Leslie, Søren Buus, David A. Price, and Philip Goulder. Programmed Death-1 Expression on HIV-1-Specific CD8+ T Cells Is Shaped by Epitope Specificity, T-Cell Receptor Clonotype Usage and Antigen Load. AIDS, 28(14):2007-2021, 10 Sep 2014. PubMed ID: 24906112. Show all entries for this paper.


Displaying record number 59314

HXB2 Location Gag(22-30)
p17(22-30)
DNA(853..879)
Gag Epitope Map
Author Location Gag(22-30)
Epitope RPGGKKHYM Epitope Alignment
RPGGKKHYM epitope logo
Show epitope variants
Epitope Name Gag-RM9
Subtype C
Species (MHC/HLA) human(B*4201)
Immunogen HIV-1 infection
Country Botswana, South Africa, United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, Other, Tetramer binding
Keywords immunodominance, escape, optimal epitope, novel epitope

Notes

References

Kloverpris2015 Henrik N Kløverpris, Reuben McGregor, James E. McLaren, Kristin Ladell, Mikkel Harndahl, Anette Stryhn, Jonathan M. Carlson, Catherine Koofhethile, Bram Gerritsen, Can Keşmir, Fabian Chen, Lynn Riddell, Graz Luzzi, Alasdair Leslie, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, David A. Price, and Philip J. Goulder. CD8+ TCR Bias and Immunodominance in HIV-1 Infection. J. Immunol., 194(11):5329-5345, 1 Jun 2015. PubMed ID: 25911754. Show all entries for this paper.


Displaying record number 58700

HXB2 Location Gag(22-30)
p17(22-30)
DNA(853..879)
Gag Epitope Map
Author Location p17(22-30)
Epitope RPGGKKHYM Epitope Alignment
RPGGKKHYM epitope logo
Show epitope variants
Epitope Name p17-RM9
Subtype C
Species (MHC/HLA) human(B*4201, B*4202)
Immunogen HIV-1 infection
Patient MHC/HLA A*3001, B*4201, Cw*1701; A*3001, B*4202, Cw*1701
Country Botswana, South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Other, Tetramer binding
Keywords HLA associated polymorphism, novel epitope

Notes

References

Kloverpris2012a Henrik N. Kløverpris, Mikkel Harndahl, Alasdair J. Leslie, Jonathan M. Carlson, Nasreen Ismail, Mary van der Stok, Kuan-Hsiang Gary Huang, Fabian Chen, Lynn Riddell, Dewald Steyn, Dominique Goedhals, Cloete van Vuuren, John Frater, Bruce D. Walker, Mary Carrington, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HIV Control through a Single Nucleotide on the HLA-B Locus. J. Virol., 86(21):11493-11500, Nov 2012. PubMed ID: 22896606. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Operated by Los Alamos National Security, LLC, for the U.S. Department of Energy's National Nuclear Security Administration
Copyright © 2006-2017 LANS LLC All rights reserved | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health