HIV molecular immunology database
Found 13 matching records:
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev(66-75) | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Epitope Name | RL10 | |
Species (MHC/HLA) | human(A*80) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev(66-75) | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Epitope Name | RL10 | |
Species (MHC/HLA) | human(B*07) | |
Immunogen | HIV-1 infection | |
Experimental methods | CTL suppression of replication | |
Keywords | class I down-regulation by Nef |
Adnan2006 Sama Adnan, Arumugam Balamurugan, Alicja Trocha, Michael S. Bennett, Hwee L. Ng, Ayub Ali, Christian Brander, and Otto O. Yang. Nef Interference with HIV-1-Specific CTL Antiviral Activity Is Epitope Specific. Blood, 108(10):3414-3419, 15 Nov 2006. PubMed ID: 16882705. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | RL10 | |
Subtype | A, B, C, D, F, G | |
Species (MHC/HLA) | human(B*07) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | Chromium-release assay, Other | |
Keywords | subtype comparisons |
Bennett2008 Michael S. Bennett, Hwee L. Ng, Ayub Ali, and Otto O. Yang. Cross-Clade Detection of HIV-1-Specific Cytotoxic T Lymphocytes Does Not Reflect Cross-Clade Antiviral Activity. J. Infect. Dis., 197(3):390-397, 1 Feb 2008. PubMed ID: 18184090. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev(66-75) | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | RL10 | |
Subtype | B | |
Species (MHC/HLA) | human(B*07) | |
Immunogen | in vitro stimulation or selection | |
Experimental methods | Chromium-release assay, Cytokine production, Gene expression assay/analyses, Other | |
Keywords | characterizing CD8+ T cells |
Grossman2019 Mark A. Grossman, Christian Hofmann, Hwee L. Ng, and Otto O. Yang. Suboptimal Stimulation by Weak Agonist Epitope Variants Does Not Drive Dysfunction of HIV-1-Specific Cytotoxic T Lymphocyte Clones. AIDS, 33(10):1565-1574, 1 Aug 2019. PubMed ID: 31306165. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev(66-75) | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Epitope Name | RL10 | |
Species (MHC/HLA) | human(B*07) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | ||
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Epitope Name | RL10 | |
Species (MHC/HLA) | human(B*07) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Epitope Name | RL10-Rev | |
Subtype | B, C | |
Species (MHC/HLA) | human(B*07:02) | |
Immunogen | HIV-1 infection | |
Country | Japan, South Africa, United Kingdom, United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, HLA binding | |
Keywords | binding affinity, subtype comparisons |
Kloverpris2014 Henrik N. Kløverpris, Emily Adland, Madoka Koyanagi, Anette Stryhn, Mikkel Harndahl, Philippa C. Matthews, Roger Shapiro, Bruce D. Walker, Thumbi Ndung'u, Christian Brander, Masafumi Takiguchi, Søren Buus, and Philip Goulder. HIV Subtype Influences HLA-B*07:02-Associated HIV Disease Outcome. AIDS Res. Hum. Retroviruses, 30(5):468-475, May 2014. PubMed ID: 24010680. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev(66-75) | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | RL10 | |
Subtype | B | |
Species (MHC/HLA) | human(B*07:02) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other | |
Keywords | acute/early infection, variant cross-reactivity |
Du2016 Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, and Paul A. Goepfert. HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection. J. Immunol., 196(8):3276-3286, 15 Apr 2016. PubMed ID: 26983786. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev(66-75) | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Epitope Name | Rev-RL10 | |
Subtype | C | |
Species (MHC/HLA) | human(B*42:02) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*30:01, B*42:02, C*17:01 | |
Country | Botswana, South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | HLA associated polymorphism, novel epitope |
Kloverpris2012a Henrik N. Kløverpris, Mikkel Harndahl, Alasdair J. Leslie, Jonathan M. Carlson, Nasreen Ismail, Mary van der Stok, Kuan-Hsiang Gary Huang, Fabian Chen, Lynn Riddell, Dewald Steyn, Dominique Goedhals, Cloete van Vuuren, John Frater, Bruce D. Walker, Mary Carrington, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HIV Control through a Single Nucleotide on the HLA-B Locus. J. Virol., 86(21):11493-11500, Nov 2012. PubMed ID: 22896606. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev(66-75) | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Epitope Name | RL10 | |
Species (MHC/HLA) | human(B7) | |
Immunogen | HIV-1 infection | |
Experimental methods | Chromium-release assay, Other | |
Keywords | binding affinity |
Bennett2007 Michael S. Bennett, Hwee L. Ng, Mirabelle Dagarag, Ayub Ali, and Otto O. Yang. Epitope-Dependent Avidity Thresholds for Cytotoxic T-Lymphocyte Clearance of Virus-Infected Cells. J. Virol., 81(10):4973-4980, May 2007. PubMed ID: 17329324. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev(66-75) | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B7) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | 17543: A*01:01, A*02:02, B*07:02, B*15:03, C*02:10, C*07:02 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | acute/early infection |
Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev(66-75) | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Epitope Name | RL10 | |
Species (MHC/HLA) | human(C*12) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Rev(66-75) DNA(8498..8527) |
Rev Epitope Map |
---|---|---|
Author Location | Rev(66-75) | |
Epitope |
RPAEPVPLQL
|
Epitope Alignment
|
Epitope Name | RL10 | |
Species (MHC/HLA) | human(C*17) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.