HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 61149

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HXB2 Location Gag(275-282)
p24(143-150)
DNA(1612..1635)
Gag Epitope Map
Author Location  
Epitope RMYSPVSI Epitope Alignment
RMYSPVSI epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human, mouse(B*52:01)
Immunogen HIV-1 infection, vaccine
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type DNA, modified vaccinia Ankara (MVA), adenovirus
Vaccine strain B clade

Notes

References

Ondondo2016 Beatrice Ondondo, Hayato Murakoshi, Genevieve Clutton, Sultan Abdul-Jawad, Edmund G.-T. Wee, Hiroyuki Gatanaga, Shinichi Oka, Andrew J. McMichael, Masafumi Takiguchi, Bette Korber, and Tomáš Hanke. Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection. Mol. Ther., 24(4):832-842, Apr 2016. PubMed ID: 26743582. Show all entries for this paper.


Displaying record number 61539

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HXB2 Location Gag(275-282)
p24(143-150)
DNA(1612..1635)
Gag Epitope Map
Author Location p24(143-150)
Epitope RMYSPVSI Epitope Alignment
RMYSPVSI epitope logo
Show epitope variants
Epitope Name Gag p24 RI8-6V
Subtype CRF01_AE
Species (MHC/HLA) human(B*52:01)
Immunogen HIV-1 infection
Patient MHC/HLA KI-724: B*52:01, C*01:02
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords subtype comparisons, variant cross-reactivity, optimal epitope, novel epitope, chronic infection

Notes

References

Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.


Displaying record number 62765

Download this epitope record as JSON.

HXB2 Location Gag(275-282)
p24(143-150)
DNA(1612..1635)
Gag Epitope Map
Author Location Gag(275-282)
Epitope RMYSPVSI Epitope Alignment
RMYSPVSI epitope logo
Show epitope variants
Epitope Name RI8
Subtype C
Species (MHC/HLA) human(B*52:01)
Immunogen HIV-1 infection
Country India
Experimental methods Other, Relative replication capacity assay
Keywords viral fitness and reversion, HLA associated polymorphism, compensatory mutation, chronic infection, protective allele

Notes

References

Tsai2020 Ming-Han Chloe Tsai, Supriya Singh, Emily Adland, and Philip Goulder. Impact of HLA-B*52:01-Driven Escape Mutations on Viral Replicative Capacity. J. Virol., 94(13), 16 Jun 2020. PubMed ID: 32321820. Show all entries for this paper.


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