HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 53957

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HXB2 Location Gag(20-29)
p17(20-29)
DNA(847..876)
Gag Epitope Map
Author Location ( C consensus)
Epitope RLRPGGKKHY Epitope Alignment
RLRPGGKKHY epitope logo
Subtype C
Species (MHC/HLA) human(A*30:02)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 56587

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HXB2 Location Gag(20-29)
p17(20-29)
DNA(847..876)
Gag Epitope Map
Author Location p17(20-29)
Epitope RLRPGGKKHY Epitope Alignment
RLRPGGKKHY epitope logo
Epitope Name RY10
Subtype C
Species (MHC/HLA) human(B*42:01)
Immunogen HIV-1 infection
Country South Africa, Zambia
Experimental methods  
Keywords viral fitness and reversion, HLA associated polymorphism

Notes

References

Goepfert2008 Paul A. Goepfert, Wendy Lumm, Paul Farmer, Philippa Matthews, Andrew Prendergast, Jonathan M. Carlson, Cynthia A. Derdeyn, Jianming Tang, Richard A. Kaslow, Anju Bansal, Karina Yusim, David Heckerman, Joseph Mulenga, Susan Allen, Philip J. R. Goulder, and Eric Hunter. Transmission of HIV-1 Gag Immune Escape Mutations Is Associated with Reduced Viral Load in Linked Recipients. J. Exp. Med., 205(5):1009-1017, 12 May 2008. PubMed ID: 18426987. Show all entries for this paper.


Displaying record number 57875

Download this epitope record as JSON.

HXB2 Location Gag(20-29)
p17(20-29)
DNA(847..876)
Gag Epitope Map
Author Location p17
Epitope RLRPGGKKHY Epitope Alignment
RLRPGGKKHY epitope logo
Show epitope variants
Subtype C
Species (MHC/HLA) human(B*42:01)
Immunogen HIV-1 infection
Patient MHC/HLA CAP239: A*01:01, A*29:02, B*42:01, B*58:01, C*06:02, C*07:02
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, escape, acute/early infection

Notes

References

Chopera2011 D. R. Chopera, M. Mlotshwa, Z. Woodman, K. Mlisana, D. de Assis Rosa, D. P. Martin, S. Abdool Karim, C. M. Gray, C. Williamson, and CAPRISA 002 Study Team. Virological and Immunological Factors Associated with HIV-1 Differential Disease Progression in HLA-B*58:01-Positive Individuals. J. Virol., 85(14):7070-7080, Jul 2011. PubMed ID: 21613398. Show all entries for this paper.


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