HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 24 matching records:

Displaying record number 53102

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location Env(786-778)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Country Spain
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Proliferation
Keywords HAART, ART, supervised treatment interruptions (STI)

Notes

References

Plana2004 Montserrat Plana, Felipe Garcia, Annette Oxenius, Gabriel M. Ortiz, Anna Lopez, Anna Cruceta, Gabriel Mestre, Emilio Fumero, Catherine Fagard, Maria Antonia Sambeat, Ferran Segura, José M. Miró, Mireia Arnedo, L. Lopalcos, Tomas Pumarola, Bernard Hirschel, Rodney E. Phillips, Douglas F. Nixon, Teresa Gallart, and Jose M. Gatell. Relevance of HIV-1-Specific CD4+ Helper T-Cell Responses During Structured Treatment Interruptions in Patients With CD4+ T-Cell Nadir Above 400/mm3. J. Acquir. Immune Defic. Syndr., 36(3):791-799, 1 Jul 2004. PubMed ID: 15213562. Show all entries for this paper.


Displaying record number 57293

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location  
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Epitope Name RR11
Subtype B
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Country Barbados, Haiti, Jamaica
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords mother-to-infant transmission, elite controllers

Notes

References

Schneidewind2009 Arne Schneidewind, Yanhua Tang, Mark A. Brockman, Elizabeth G. Ryland, Jacqueline Dunkley-Thompson, Julianne C. Steel-Duncan, M. Anne St. John, Joseph A. Conrad, Spyros A. Kalams, Francine Noel, Todd M. Allen, Celia D. Christie, and Margaret E. Feeney. Maternal Transmission of Human Immunodeficiency Virus Escape Mutations Subverts HLA-B57 Immunodominance but Facilitates Viral Control in the Haploidentical Infant. J. Virol., 83(17):8616-8627, Sep 2009. PubMed ID: 19515764. Show all entries for this paper.


Displaying record number 1779

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(770-780)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Experimental methods  
Keywords rate of progression, acute/early infection

Notes

References

Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.


Displaying record number 1780

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location Nef(73-82)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Experimental methods  
Keywords rate of progression, acute/early infection

Notes

References

Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.


Displaying record number 60127

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location Env(770-780)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Epitope Name RR11
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 58980

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(259-269)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Subtype B
Species (MHC/HLA) human(A*0301)
Immunogen HIV-1 infection
Country Australia, Canada, Spain, Switzerland
Experimental methods Other
Keywords mutation acquisition

Notes

References

Bartha2013 István Bartha, Jonathan M. Carlson, Chanson J. Brumme, Paul J. McLaren, Zabrina L. Brumme, Mina John, David W. Haas, Javier Martinez-Picado, Judith Dalmau, Cecilio López-Galíndez, Concepción Casado, Andri Rauch, Huldrych F. Günthard, Enos Bernasconi, Pietro Vernazza, Thomas Klimkait, Sabine Yerly, Stephen J. O'Brien, Jennifer Listgarten, Nico Pfeifer, Christoph Lippert, Nicolo Fusi, Zoltán Kutalik, Todd M. Allen, Viktor Müller, P. Richard Harrigan, David Heckerman, Amalio Telenti, and Jacques Fellay. A Genome-to-Genome Analysis of Associations between Human Genetic Variation, HIV-1 Sequence Diversity, and Viral Control. eLife, 2:e01123, 2013. PubMed ID: 24171102. Show all entries for this paper.


Displaying record number 1121

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(775-785 LAI)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Subtype B
Species (MHC/HLA) human(A*0301)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 863

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(768-778 NL43)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A*0301)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Takahashi1991 K. Takahashi, L.-C. Dai, T. R. Fuerst, W. E. Biddison, P. L. Earl, B. Moss, and F. A. Ennis. Specific Lysis of Human Immunodeficiency Virus Type 1-Infected Cells by a HLA-A3.1-Restricted CD8+ Cytotoxic T-Lymphocyte Clone That Recognizes a Conserved Peptide Sequence within the gp41 Subunit of the Envelope Protein. Proc. Natl. Acad. Sci. U.S.A., 88:10277-10281, 1991. gp41 epitope: RLRDLLLIVTR, HLA A3.1 (NL43). Synthetic peptides of RF and CDC4 were recognized by CTL clone despite non-conservative Thr to (Val or Ala) change, but an MN peptide with four natural substitutions was not recognized. PubMed ID: 1719555. Show all entries for this paper.


Displaying record number 1653

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(775-785)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A3)
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


Displaying record number 864

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(768-778 NL43)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Show epitope variants
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons

Notes

References

Cao1997a H. Cao, P. Kanki, J. L. Sankale, A. Dieng-Sarr, Gail P. Mazzara, S. Kalams, B. Korber, S. M'Boup, and B. D. Walker. CTL Cross-Reactivity among Different HIV-1 Clades: Implications for Vaccine Development. J. Virol., 71:8615-8623, 1997. PubMed ID: 9343219. Show all entries for this paper.


Displaying record number 52149

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(769-780)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Epitope Name A3-RR11
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A3, B7, Cw7
Experimental methods  
Keywords dynamics, supervised treatment interruptions (STI), acute/early infection

Notes

References

Yu2002b Xu G. Yu, Marylyn M. Addo, Eric S. Rosenberg, William R. Rodriguez, Paul K. Lee, Cecily A. Fitzpatrick, Mary N. Johnston, Daryld. Strick, Philip J. R. Goulder, Bruce D. Walker, and Marcus Altfeld. Consistent Patterns in the Development and Immunodominance of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T-Cell Responses Following Acute HIV-1 Infection. J. Virol., 76(17):8690-8701, Sep 2002. PubMed ID: 12163589. Show all entries for this paper.


Displaying record number 52990

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location Env(770-780)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Show epitope variants
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A3, A32, B15, B51, Cw03, Cw6, DQ7, DR4, DR8
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, escape

Notes

References

Geels2003 Mark J. Geels, Marion Cornelissen, Hanneke Schuitemaker, Kiersten Anderson, David Kwa, Jolanda Maas, John T. Dekker, Elly Baan, Fokla Zorgdrager, Remco van den Burg, Martijn van Beelen, Vladimir V. Lukashov, Tong-Ming Fu, William A. Paxton, Lia van der Hoek, Sheri A. Dubey, John W. Shiver, and Jaap Goudsmit. Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual. J. Virol., 77(23):12430-12440, Dec 2003. PubMed ID: 14610167. Show all entries for this paper.


Displaying record number 55018

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location  
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A3, A31)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, immunodominance, optimal epitope

Notes

References

Bihl2006 Florian Bihl, Nicole Frahm, Loriana Di Giammarino, John Sidney, Mina John, Karina Yusim, Tonia Woodberry, Kaori Sango, Hannah S. Hewitt, Leah Henry, Caitlyn H. Linde, John V. Chisholm, III, Tauheed M. Zaman, Eunice Pae, Simon Mallal, Bruce D Walker, Alessandro Sette, Bette T. Korber, David Heckerman, and Christian Brander. Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses. J. Immunol., 176(7):4094-4101, 1 Apr 2006. PubMed ID: 16547245. Show all entries for this paper.


Displaying record number 56428

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp160
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Epitope Name RR11(gp160)
Subtype B
Species (MHC/HLA) human(A3, A31)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55192

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location  
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A3, A31)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords supertype, HLA cross-presentation

Notes

References

Frahm2007b Nicole Frahm, Karina Yusim, Todd J. Suscovich, Sharon Adams, John Sidney, Peter Hraber, Hannah S. Hewitt, Caitlyn H. Linde, Daniel G. Kavanagh, Tonia Woodberry, Leah M. Henry, Kellie Faircloth, Jennifer Listgarten, Carl Kadie, Nebojsa Jojic, Kaori Sango, Nancy V. Brown, Eunice Pae, M. Tauheed Zaman, Florian Bihl, Ashok Khatri, Mina John, Simon Mallal, Francesco M. Marincola, Bruce D . Walker, Alessandro Sette, David Heckerman, Bette T. Korber, and Christian Brander. Extensive HLA Class I Allele Promiscuity among Viral CTL Epitopes. Eur. J. Immunol., 37(9):2419-2433, Sep 2007. PubMed ID: 17705138. Show all entries for this paper.


Displaying record number 60125

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location Env(770-780)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Epitope Name RR11
Species (MHC/HLA) human(A*31)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 52919

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location Env
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Epitope Name RR11
Subtype C
Species (MHC/HLA) human(A31)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords epitope processing, escape

Notes

References

Draenert2004a Rika Draenert, Sylvie Le Gall, Katja J. Pfafferott, Alasdair J. Leslie, Polan Chetty, Christian Brander, Edward C. Holmes, Shih-Chung Chang, Margaret E. Feeney, Marylyn M. Addo, Lidia Ruiz, Danni Ramduth, Prakash Jeena, Marcus Altfeld, Stephanie Thomas, Yanhua Tang, Cori L. Verrill, Catherine Dixon, Julia G. Prado, Photini Kiepiela, Javier Martinez-Picado, Bruce D. Walker, and Philip J. R. Goulder. Immune Selection for Altered Antigen Processing Leads to Cytotoxic T Lymphocyte Escape in Chronic HIV-1 Infection. J. Exp. Med., 199(7):905-915, 5 Apr 2004. PubMed ID: 15067030. Show all entries for this paper.


Displaying record number 866

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(770-780)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A31)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Ferris1999 R. L. Ferris, C. Hall, N. V. Sipsas, J. T. Safrit, A. Trocha, R. A. Koup, R. P. Johnson, and R. F. Siliciano. Processing of HIV-1 Envelope Glycoprotein for Class I-Restricted Recognition: Dependence on TAP1/2 and Mechanisms for Cytosolic Localization. J. Immunol., 162:1324-1332, 1999. PubMed ID: 9973386. Show all entries for this paper.

Hammond1995 S. A. Hammond, R. P. Johnson, S. A. Kalams, B. D. Walker, M. Takiguchi, J. T. Safrit, R. A. Koup, and R. F. Siliciano. An Epitope-Selective Transporter Associated with Antigen Presentation TAP-1/2-Independent Pathway and a More General TAP-1/2-Dependent Antigen-Processing Pathway Allow Recognition of the HIV-1 Envelope Glycoprotein by CD8+ CTL. J. Immunol., 154:6140-6156, 1995. Two peptide-processing pathways are utilized for MHC class I presentation of HIV-1 Env epitopes. The previously characterized TAP-1 and TAP-2 dependent pathway can generate all Env epitopes and uses Env protein mislocalized in the cytosol to produce peptides. The second, novel pathway uses a TAP-1/2 independent pathway, and allows a subset of MHC-restricted epitopes to be processed in the endoplasmic reticulum or a Golgi compartment. PubMed ID: 7538543. Show all entries for this paper.


Displaying record number 52632

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(770-780)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A31)
Immunogen HIV-1 infection
Patient MHC/HLA A*0201, A31, B44, B60, Cw16, Cw3
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords binding affinity, acute/early infection, early-expressed proteins

Notes

References

Cao2003 Jianhong Cao, John McNevin, Sarah Holte, Lisa Fink, Lawrence Corey, and M. Juliana McElrath. Comprehensive Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon-Secreting CD8+ T Cells in Primary HIV-1 Infection. J. Virol., 77(12):6867-6878, Jun 2003. PubMed ID: 12768006. Show all entries for this paper.


Displaying record number 1199

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp160(770-780 LAI)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Subtype B
Species (MHC/HLA) human(A*3101)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 865

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(770-780 BH10)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A*3101)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Safrit1994a J. T. Safrit, C. A. Andrews, T. Zhu, D. D. Ho, and R. A. Koup. Characterization of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocyte Clones Isolated during Acute Seroconversion: Recognition of Autologous Virus Sequences within a Conserved Immunodominant Epitope. J. Exp. Med., 179:463-472, 1994. HIV-1 specific CTL clones were isolated from two individuals at acute seroconversion. In one patient, two HLA A31-restricted clones recognized the same fragment of gp41, peptide RLRDLLLIVTR, but one was sensitive to a Thr to Val substitution, while the other was not. A CTL HLA A32-restricted clone from the other patient recognized the gp41 peptide VLSIVNRVRQGYSPLSFQTH. Autologous viral sequences from seroconversion were recognized by the CTL clones, but not the HIV-1 strain MN. PubMed ID: 8294860. Show all entries for this paper.

Safrit1994b J. T. Safrit, A. Y. Lee, C. A. Andrews, and R. A. Koup. A Region of the Third Variable Loop of HIV-1 gp120 Is Recognized by HLA-B7-Restricted CTLs from Two Acute Seroconversion Patients. J. Immunol., 153:3822-3830, 1994. HIV-1 envelope-specific CTL clones were isolated from the peripheral blood of two patients within weeks of seroconversion. These clones were CD8+ and restricted by the HLA-B7 molecule. The minimum epitope was defined, RPNNNTRKSI, with anchor residues at the proline and isoleucine; the anchor residues are relatively well conserved. A Serine to Arginine change at position 9 of the epitope abrogated clone recognition in one of the patients. This amino acid change is one factor that has been associated with a change from a nonsyncytium-inducing to a syncytium-inducing phenotype of HIV-1.. PubMed ID: 7523505. Show all entries for this paper.


Displaying record number 60128

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location Env(770-780)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Epitope Name RR11
Species (MHC/HLA) human(A*34)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60126

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location Env(770-780)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Epitope Name RR11
Species (MHC/HLA) human(A*74)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 1122

HXB2 Location gp160(770-780)
gp41(259-269)
DNA(8532..8564)
gp160 Epitope Map
Author Location gp41(775-785)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection
Experimental methods  
Keywords immunodominance

Notes

References

Betts2000 M. R. Betts, J. P. Casazza, B. A. Patterson, S. Waldrop, W. Trigona, T.-M Fu, F. Kern, L. J. Picker, and R. A. Koup. Putative Immunodominant Human Imunodeficiency Virus-Specific CD8+ T Cell Responses Cannot Be Predicted by Major Histocompatibility Complex Class I Haplotype. J. Virol., 74:9144-9151, 2000. PubMed ID: 10982361. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Operated by Los Alamos National Security, LLC, for the U.S. Department of Energy's National Nuclear Security Administration
Copyright © 2006-2017 LANS LLC All rights reserved | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health