HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 54962

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HXB2 Location Nef(188-196)
DNA(9358..9384)
Nef Epitope Map
Author Location Nef(188-196)
Epitope RLAFHHVAR Epitope Alignment
RLAFHHVAR epitope logo
Species (MHC/HLA) (A11, A3)
Immunogen peptide-HLA interaction
Experimental methods HLA binding
Keywords binding affinity, immunodominance

Notes

References

Racape2006a Judith Racape, Francine Connan, Johan Hoebeke, Jeannine Choppin, and Jean-Gérard Guillet. Influence of Dominant HIV-1 Epitopes on HLA-A3/Peptide Complex Formation. Proc. Natl. Acad. Sci. U.S.A., 103(48):18208-18213, 28 Nov 2006. PubMed ID: 17116886. Show all entries for this paper.


Displaying record number 1093

Download this epitope record as JSON.

HXB2 Location Nef(188-196)
DNA(9358..9384)
Nef Epitope Map
Author Location Nef(188-196 LAI)
Epitope RLAFHHVAR Epitope Alignment
RLAFHHVAR epitope logo
Subtype B
Species (MHC/HLA) human(B52)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Hadida1995 F. Hadida, G. Haas, G. Zimmermann, A. Hosmalin, R. Spohn, A. Samri, G. Jung, P. Debre, and B. Autran. CTLs from Lymphoid Organs Recognize an Optimal HLA-A2 Restricted and HLA-B52 Restricted Nonapeptide and Several Epitopes in the C-Terminal Region of HIV-1 Nef. J. Immunol., 154:4174-4186, 1995. An in vitro limiting dilution analysis showed CTL recognition in the context of HLA B52 and A2.1, A2.2 and A2.4 in nanomolar concentrations. Molecular modeling suggests motifs important for peptide binding to the pocket of an HLA-A2.1 molecule. PubMed ID: 7535824. Show all entries for this paper.


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