HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 1583

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HXB2 Location Tat(49-57)
DNA(5975..6001)
Tat Epitope Map
Author Location Tat(49-57)
Epitope RKKRRQRRR Epitope Alignment
RKKRRQRRR epitope logo
Species (MHC/HLA) mouse(H-2d)
Immunogen vaccine
Experimental methods  
Keywords Th1

Vaccine Details

Vaccine type DNA, DNA with protein boost
Vaccine strain B clade LAI
Vaccine component Gag, Nef, Tat
Adjuvant IL-18

Notes

References

BillautMulot2001 O. Billaut-Mulot, T. Idziorek, M. Loyens, A. Capron, and G. M. Bahr. Modulation of cellular and humoral immune responses to a multiepitopic HIV-1 DNA vaccine by interleukin-18 DNA immunization/viral protein boost. Vaccine, 19(20-22):2803-11, 6 Apr 2001. PubMed ID: 11282190. Show all entries for this paper.


Displaying record number 609

Download this epitope record as JSON.

HXB2 Location Tat(49-57)
DNA(5975..6001)
Tat Epitope Map
Author Location Tat(49-57)
Epitope RKKRRQRRR Epitope Alignment
RKKRRQRRR epitope logo
Species (MHC/HLA) mouse
Immunogen  
Experimental methods  
Keywords  

Notes

References

Kim1997b D. T. Kim, D. J. Mitchell, D. G. Brockstedt, L. Fong, G. P. Nolan, C. G. Fathman, E. G. Engleman, and J. B. Rothbard. Introduction of Soluble Proteins into the MHC Class I Pathway by Conjugation to an HIV Tat Peptide. J. Immunol., 159(4):1666-1668, 1997. A vaccine based on the conjugation of OVA to an HIV Tat peptide that enhances protein uptake by APC cells stimulated MHC Class I-restricted T cell response in vitro and CTL generation in vivo in a murine system. PubMed ID: 9257826. Show all entries for this paper.


Displaying record number 58836

Download this epitope record as JSON.

HXB2 Location Tat(49-57)
DNA(5975..6001)
Tat Epitope Map
Author Location Tat(49-57)
Epitope RKKRRQRRR Epitope Alignment
RKKRRQRRR epitope logo
Epitope Name Tat49-57
Species (MHC/HLA) mouse
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords vaccine antigen design

Vaccine Details

Vaccine type nanoparticle
Vaccine component other
Adjuvant Incomplete Freund's Adjuvant (IFA)

Notes

References

Tang2012 Jun Tang, Rui Yin, Yi Tian, Zeming Huang, Jinglei Shi, Xiaolan Fu, Li Wang, Yuzhang Wu, Fei Hao, and Bing Ni. A Novel Self-Assembled Nanoparticle Vaccine with HIV-1 Tat(49--57)/HPV16 E7(49--57) Fusion Peptide and GM-CSF DNA Elicits Potent and Prolonged CD8+ T Cell-Dependent Anti-Tumor Immunity in Mice. Vaccine, 30(6):1071-1082, 1 Feb 2012. PubMed ID: 22178528. Show all entries for this paper.


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