HIV molecular immunology database
Found 12 matching records:
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(419-427) | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Epitope Name | RW9 | |
Species (MHC/HLA) | human(A*32) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120 | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Epitope Name | RW9(gp120) | |
Subtype | B | |
Species (MHC/HLA) | human(A32) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | chronic infection |
Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120(420-428) | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Species (MHC/HLA) | human(A32) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords |
Ferris1999 R. L. Ferris, C. Hall, N. V. Sipsas, J. T. Safrit, A. Trocha, R. A. Koup, R. P. Johnson, and R. F. Siliciano. Processing of HIV-1 Envelope Glycoprotein for Class I-Restricted Recognition: Dependence on TAP1/2 and Mechanisms for Cytosolic Localization. J. Immunol., 162:1324-1332, 1999. PubMed ID: 9973386. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120 | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Epitope Name | A32-RW10(gp120) | |
Subtype | B | |
Species (MHC/HLA) | human(A32) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A32, B44; A30, A32, B18, B27 | |
Experimental methods | ||
Keywords | HAART, ART, supervised treatment interruptions (STI) |
Altfeld2002 Marcus Altfeld, Jan van Lunzen, Nicole Frahm, Xu G. Yu, Claus Schneider, Robert L. Eldridge, Margaret E. Feeney, Dirk Meyer-Olson, Hans-Juergen Stellbrink, and Bruce D. Walker. Expansion of Pre-existing, Lymph Node-localized CD8+ T Cells During Supervised Treatment Interruptions in Chronic HIV-1 Infection. J. Clin. Invest., 109(6):837-843, Mar 2002. PubMed ID: 11901192. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(424-432 BRU) | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Subtype | B, CRF02_AG | |
Species (MHC/HLA) | human(A32) | |
Immunogen | HIV-1 infection | |
Country | Cote D'Ivoire | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | subtype comparisons |
Inwoley2005 André Inwoley, Patricia Recordon-Pinson, Marion Dupuis, Jessintha Gaston, Mathieu Genête, Albert Minga, Franck Letourneur, François Rouet, Jeannine Choppin, Hervé Fleury, Jean-Gérard Guillet, Muriel Andrieu, and ANRS 1220 PRIMO-CI Study Group. Cross-Clade Conservation of HIV Type 1 Nef Immunodominant Regions Recognized by CD8+ T Cells of HIV Type 1 CRF02\_AG-Infected Ivorian (West Africa). AIDS Res. Hum. Retroviruses, 21(7):620-628, Jul 2005. PubMed ID: 16060833. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120(424-432 HXB2) | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Show epitope variants | ||
Subtype | B | |
Species (MHC/HLA) | human(A*32:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | 15160: A*03, A*32, B*14, B*44 | |
Country | United States | |
Experimental methods | Chromium-release assay | |
Keywords | autologous responses, novel epitope |
Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120(419-427 HXB2) | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(A*32:01) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | ||
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(A*32:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A*32:04, A*74:12, B*07:02, B*44:03, C*02:10, C*07:02 | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay | |
Keywords | rate of progression |
Gray2009 Clive M. Gray, Mandla Mlotshwa, Catherine Riou, Tiyani Mathebula, Debra de Assis Rosa, Tumelo Mashishi, Cathal Seoighe, Nobubelo Ngandu, Francois van Loggerenberg, Lynn Morris, Koleka Mlisana, Carolyn Williamson, Salim Abdool Karim, and CAPRISA 002 Acute Infection Study Team. Human Immunodeficiency Virus-Specific gamma Interferon Enzyme-Linked Immunospot Assay Responses Targeting Specific Regions of the Proteome during Primary Subtype C Infection Are Poor Predictors of the Course of Viremia and Set Point. J. Virol., 83(1):470-478, Jan 2009. PubMed ID: 18945774. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(419-427) | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Epitope Name | RW9 | |
Species (MHC/HLA) | human(C*06) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(419-427) | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Epitope Name | RW9 | |
Species (MHC/HLA) | human(C*12) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | Env | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | EnvRW9 | |
Subtype | A, B, C, D | |
Species (MHC/HLA) | human | |
Immunogen | vaccine | |
Patient MHC/HLA | Subject A: A*01, A*26, B*56:01, B*57, C*01, C*06 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other | |
Keywords | subtype comparisons, vaccine-induced immune responses |
Vaccine type | DNA prime with Ad5 boost |
---|---|
Vaccine strain | A clade, B clade, C clade |
Koup2010 Richard A. Koup, Mario Roederer, Laurie Lamoreaux, Jennifer Fischer, Laura Novik, Martha C. Nason, Brenda D. Larkin, Mary E. Enama, Julie E. Ledgerwood, Robert T. Bailer, John R. Mascola, Gary J. Nabel, Barney S. Graham, VRC 009 Study Team, and VRC 010 Study Team. Priming Immunization with DNA Augments Immunogenicity of Recombinant Adenoviral Vectors for Both HIV-1 Specific Antibody and T-Cell Responses. PLoS One, 5(2):e9015, 2010. PubMed ID: 20126394. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(419-427) gp120(419-427) DNA(7479..7505) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120(419-427) | |
Epitope |
RIKQIINMW
|
Epitope Alignment
|
Epitope Name | RW9 | |
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A26, A32, B27, Cw1, Cw2 | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | HIV exposed persistently seronegative (HEPS), acute/early infection |
Liu2009b Yi Liu, Amanda Woodward, Haiying Zhu, Thomas Andrus, John McNevin, Jean Lee, James I. Mullins, Lawrence Corey, M. Juliana McElrath, and Tuofu Zhu. Preinfection Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T Lymphocytes Failed to Prevent HIV Type 1 Infection from Strains Genetically Unrelated to Viruses in Long-Term Exposed Partners. J. Virol., 83(20):10821-10829, Oct 2009. PubMed ID: 19706711. Show all entries for this paper.