HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 12 matching records:

Displaying record number 55956

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location gp120
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Epitope Name RW9(gp120)
Subtype B
Species (MHC/HLA) human(A32)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 793

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location gp120(420-428)
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Species (MHC/HLA) human(A32)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Ferris1999 R. L. Ferris, C. Hall, N. V. Sipsas, J. T. Safrit, A. Trocha, R. A. Koup, R. P. Johnson, and R. F. Siliciano. Processing of HIV-1 Envelope Glycoprotein for Class I-Restricted Recognition: Dependence on TAP1/2 and Mechanisms for Cytosolic Localization. J. Immunol., 162:1324-1332, 1999. PubMed ID: 9973386. Show all entries for this paper.


Displaying record number 52277

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location gp120
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Epitope Name A32-RW10(gp120)
Subtype B
Species (MHC/HLA) human(A32)
Immunogen HIV-1 infection
Patient MHC/HLA A32, B44; A30, A32, B18, B27
Experimental methods  
Keywords HAART, ART, supervised treatment interruptions (STI)

Notes

References

Altfeld2002 Marcus Altfeld, Jan van Lunzen, Nicole Frahm, Xu G. Yu, Claus Schneider, Robert L. Eldridge, Margaret E. Feeney, Dirk Meyer-Olson, Hans-Juergen Stellbrink, and Bruce D. Walker. Expansion of Pre-existing, Lymph Node-localized CD8+ T Cells During Supervised Treatment Interruptions in Chronic HIV-1 Infection. J. Clin. Invest., 109(6):837-843, Mar 2002. PubMed ID: 11901192. Show all entries for this paper.


Displaying record number 53730

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location Env(424-432 BRU)
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Subtype B, CRF02_AG
Species (MHC/HLA) human(A32)
Immunogen HIV-1 infection
Country Cote D'Ivoire
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons

Notes

References

Inwoley2005 André Inwoley, Patricia Recordon-Pinson, Marion Dupuis, Jessintha Gaston, Mathieu Genête, Albert Minga, Franck Letourneur, François Rouet, Jeannine Choppin, Hervé Fleury, Jean-Gérard Guillet, Muriel Andrieu, and ANRS 1220 PRIMO-CI Study Group. Cross-Clade Conservation of HIV Type 1 Nef Immunodominant Regions Recognized by CD8+ T Cells of HIV Type 1 CRF02\_AG-Infected Ivorian (West Africa). AIDS Res. Hum. Retroviruses, 21(7):620-628, Jul 2005. PubMed ID: 16060833. Show all entries for this paper.


Displaying record number 60108

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location Env(419-427)
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Epitope Name RW9
Species (MHC/HLA) human(A*32)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 791

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location gp120(424-432 HXB2)
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Subtype B
Species (MHC/HLA) human(A*3201)
Immunogen  
Experimental methods  
Keywords  

Notes

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.


Displaying record number 1136

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location gp120(419-427 HXB2)
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Subtype B
Species (MHC/HLA) human(A*3201)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 56254

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location  
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Subtype C
Species (MHC/HLA) human(A*3201)
Immunogen HIV-1 infection
Patient MHC/HLA A*3204, A*7412, B*0702, B*4403, Cw*0210, Cw*0702
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords rate of progression

Notes

References

Gray2009 Clive M. Gray, Mandla Mlotshwa, Catherine Riou, Tiyani Mathebula, Debra de Assis Rosa, Tumelo Mashishi, Cathal Seoighe, Nobubelo Ngandu, Francois van Loggerenberg, Lynn Morris, Koleka Mlisana, Carolyn Williamson, Salim Abdool Karim, and CAPRISA 002 Acute Infection Study Team. Human Immunodeficiency Virus-Specific gamma Interferon Enzyme-Linked Immunospot Assay Responses Targeting Specific Regions of the Proteome during Primary Subtype C Infection Are Poor Predictors of the Course of Viremia and Set Point. J. Virol., 83(1):470-478, Jan 2009. PubMed ID: 18945774. Show all entries for this paper.


Displaying record number 60107

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location Env(419-427)
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Epitope Name RW9
Species (MHC/HLA) human(C*06)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60109

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location Env(419-427)
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Epitope Name RW9
Species (MHC/HLA) human(C*12)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 57675

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location Env
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Show epitope variants
Epitope Name EnvRW9
Subtype A, B, C, D
Species (MHC/HLA) human
Immunogen vaccine
Patient MHC/HLA A1, A26, B*5601, B57, Cw1, Cw6
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords subtype comparisons, vaccine-induced immune responses

Vaccine Details

Vaccine type DNA prime with Ad5 boost
Vaccine strain A clade, B clade, C clade

Notes

References

Koup2010 Richard A. Koup, Mario Roederer, Laurie Lamoreaux, Jennifer Fischer, Laura Novik, Martha C. Nason, Brenda D. Larkin, Mary E. Enama, Julie E. Ledgerwood, Robert T. Bailer, John R. Mascola, Gary J. Nabel, Barney S. Graham, VRC 009 Study Team, and VRC 010 Study Team. Priming Immunization with DNA Augments Immunogenicity of Recombinant Adenoviral Vectors for Both HIV-1 Specific Antibody and T-Cell Responses. PLoS One, 5(2):e9015, 2010. PubMed ID: 20126394. Show all entries for this paper.


Displaying record number 57168

HXB2 Location gp160(419-427)
gp120(419-427)
DNA(7479..7505)
gp160 Epitope Map
Author Location gp120(419-427)
Epitope RIKQIINMW Epitope Alignment
RIKQIINMW epitope logo
Epitope Name RW9
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA A26, A32, B27, Cw1, Cw2
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HIV exposed persistently seronegative (HEPS), acute/early infection

Notes

References

Liu2009b Yi Liu, Amanda Woodward, Haiying Zhu, Thomas Andrus, John McNevin, Jean Lee, James I. Mullins, Lawrence Corey, M. Juliana McElrath, and Tuofu Zhu. Preinfection Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T Lymphocytes Failed to Prevent HIV Type 1 Infection from Strains Genetically Unrelated to Viruses in Long-Term Exposed Partners. J. Virol., 83(20):10821-10829, Oct 2009. PubMed ID: 19706711. Show all entries for this paper.


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