HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 9 matching records:

Displaying record number 1663

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HXB2 Location Gag(294-304)
p24(162-172)
DNA(1669..1701)
Gag Epitope Map
Author Location p24(296-306)
Epitope RDYVDRFFKTL Epitope Alignment
RDYVDRFFKTL epitope logo
Species (MHC/HLA) human(A24)
Immunogen HIV-1 exposed seronegative, HIV-1 infection
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


Displaying record number 54264

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HXB2 Location Gag(294-304)
p24(162-172)
DNA(1669..1701)
Gag Epitope Map
Author Location p24
Epitope RDYVDRFFKTL Epitope Alignment
RDYVDRFFKTL epitope logo
Epitope Name A24-RL11(p24)
Species (MHC/HLA) human(A24)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 57855

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HXB2 Location Gag(294-304)
p24(162-172)
DNA(1669..1701)
Gag Epitope Map
Author Location p24(162-172)
Epitope RDYVDRFFKTL Epitope Alignment
RDYVDRFFKTL epitope logo
Species (MHC/HLA) human(A*24:02)
Immunogen HIV-1 infection
Country United Kingdom
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords rate of progression, early treatment

Notes

References

Cellerai2011 Cristina Cellerai, Alexandre Harari, Hans Stauss, Sabine Yerly, Anna-Maria Geretti, Anne Carroll, Thynn Yee, Jonathan Ainsworth, Ian Williams, John Sweeney, Andrew Freedman, Margaret Johnson, Giuseppe Pantaleo, and Sabine Kinloch-de Loes. Early and Prolonged Antiretroviral Therapy Is Associated with an HIV-1-Specific T-Cell Profile Comparable to That of Long-Term Non-Progressors. PLoS One, 6(4):e18164, 2011. PubMed ID: 21483676. Show all entries for this paper.


Displaying record number 57917

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HXB2 Location Gag(294-304)
p24(162-172)
DNA(1669..1701)
Gag Epitope Map
Author Location  
Epitope RDYVDRFFKTL Epitope Alignment
RDYVDRFFKTL epitope logo
Species (MHC/HLA) human(A*24:02)
Immunogen peptide-HLA interaction
Experimental methods Tetramer binding
Keywords  

Notes

References

Fadda2011 Lena Fadda, Geraldine M. O'Connor, Swati Kumar, Alicja Piechocka-Trocha, Clair M. Gardiner, Mary Carrington, Daniel W. McVicar, and Marcus Altfeld. Common HIV-1 Peptide Variants Mediate Differential Binding of KIR3DL1 to HLA-Bw4 Molecules. J Virol, 85(12):5970-5974, Jun 2011. PubMed ID: 21471246. Show all entries for this paper.


Displaying record number 316

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HXB2 Location Gag(294-304)
p24(162-172)
DNA(1669..1701)
Gag Epitope Map
Author Location p24(296-306 subtype A)
Epitope RDYVDRFFKTL Epitope Alignment
RDYVDRFFKTL epitope logo
Show epitope variants
Subtype A
Species (MHC/HLA) human(A*24:02)
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons

Notes

References

Dorrell1999 L. Dorrell, T. Dong, G. S. Ogg, S. Lister, S. McAdam, T. Rostron, C. Conlon, A. J. McMichael, and S. L. Rowland-Jones. Distinct Recognition of Non-Clade B Human Immunodeficiency Virus Type 1 Epitopes by Cytotoxic T Lymphocytes Generated from Donors Infected in Africa. J. Virol., 73:1708-1714, 1999. PubMed ID: 9882385. Show all entries for this paper.


Displaying record number 317

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HXB2 Location Gag(294-304)
p24(162-172)
DNA(1669..1701)
Gag Epitope Map
Author Location p24(296-306 subtype A)
Epitope RDYVDRFFKTL Epitope Alignment
RDYVDRFFKTL epitope logo
Subtype A
Species (MHC/HLA) human(A*24:02)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope, A-list

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 60095

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HXB2 Location Gag(294-304)
p24(162-172)
DNA(1669..1701)
Gag Epitope Map
Author Location Gag(294-304)
Epitope RDYVDRFFKTL Epitope Alignment
RDYVDRFFKTL epitope logo
Epitope Name RL11
Species (MHC/HLA) human(A*68:02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60094

Download this epitope record as JSON.

HXB2 Location Gag(294-304)
p24(162-172)
DNA(1669..1701)
Gag Epitope Map
Author Location Gag(294-304)
Epitope RDYVDRFFKTL Epitope Alignment
RDYVDRFFKTL epitope logo
Epitope Name RL11
Species (MHC/HLA) human(C*03)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 62816

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HXB2 Location Gag(294-304)
p24(162-172)
DNA(1669..1701)
Gag Epitope Map
Author Location p24(294-304)
Epitope RDYVDRFFKTL Epitope Alignment
RDYVDRFFKTL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human
Immunogen engineered
Experimental methods Other, Relative replication capacity assay
Keywords assay or method development, protective allele

Notes

References

Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.


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