HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 55662

HXB2 Location gp160(577-587)
gp41(66-76)
DNA(7953..7985)
gp160 Epitope Map
Author Location gp41(6558-6568)
Epitope QTRVLAIERYL Epitope Alignment
QTRVLAIERYL epitope logo
Show epitope variants
Epitope Name QL11
Subtype C
Species (MHC/HLA) human(B*5801, B*5802)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords HLA associated polymorphism

Notes

References

Ngumbela2008 K. C. Ngumbela, C. L. Day, Z. Mncube, K. Nair, D. Ramduth, C. Thobakgale, E. Moodley, S. Reddy, C. de Pierres, N. Mkhwanazi, K. Bishop, M. van der Stok, N. Ismail, I. Honeyborne, H. Crawford, D. G. Kavanagh, C. Rousseau, D. Nickle, J. Mullins, D. Heckerman, B. Korber, H. Coovadia, P. Kiepiela, P. J. R. Goulder, and B. D. Walker. Targeting of a CD8 T Cell Env Epitope Presented by HLA-B*5802 Is Associated with Markers of HIV Disease Progression and Lack of Selection Pressure. AIDS Res. Hum. Retroviruses, 24(1):72-82, Jan 2008. PubMed ID: 18275350. Show all entries for this paper.


Displaying record number 54064

HXB2 Location gp160(577-587)
gp41(66-76)
DNA(7953..7985)
gp160 Epitope Map
Author Location ( C consensus)
Epitope QTRVLAIERYL Epitope Alignment
QTRVLAIERYL epitope logo
Subtype C
Species (MHC/HLA) human(B*5802)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 58620

HXB2 Location gp160(577-587)
gp41(66-76)
DNA(7953..7985)
gp160 Epitope Map
Author Location  
Epitope QTRVLAIERYL Epitope Alignment
QTRVLAIERYL epitope logo
Epitope Name QL11
Subtype C
Species (MHC/HLA) human(B*5802)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy CedeƱo, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 61579

HXB2 Location gp160(577-587)
gp41(66-76)
DNA(7953..7985)
gp160 Epitope Map
Author Location gp41(577-587)
Epitope QTRVLAIERYL Epitope Alignment
QTRVLAIERYL epitope logo
Species (MHC/HLA) human(B*5802)
Immunogen vaccine
Experimental methods Other
Keywords review, vaccine-induced immune responses, vaccine antigen design, protective allele

Notes

References

Goulder2008 Philip J. R. Goulder and David I. Watkins. Impact of MHC Class I Diversity on Immune Control of Immunodeficiency Virus Replication. Nat. Rev. Immunol., 8(8):619-630, Aug 2008. PubMed ID: 18617886. Show all entries for this paper.


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