HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 1216

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HXB2 Location gp160(103-111)
gp120(103-111)
DNA(6531..6557)
gp160 Epitope Map
Author Location Env(102-110)
Epitope QMHEDIISL Epitope Alignment
QMHEDIISL epitope logo
Species (MHC/HLA) human(A*02:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords binding affinity, TCR usage

Notes

References

Kmieciak1998b D. Kmieciak, I. Bednarek, M. Takiguchi, T. J. Wasik, J. Bratosiewicz, A. Wierzbicki, H. Teppler, J. Pientka, S. H. Hsu, Y. Kaneko, and D. Kozbor. The Effect of Epitope Variation on the Profile of Cytotoxic T Lymphocyte Responses to the HIV Envelope Glycoprotein. Int. Immunol., 10:1789-1799, 1998. PubMed ID: 9885899. Show all entries for this paper.


Displaying record number 57081

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HXB2 Location gp160(103-111)
gp120(103-111)
DNA(6531..6557)
gp160 Epitope Map
Author Location gp120(103-111 DU422)
Epitope QMHEDIISL Epitope Alignment
QMHEDIISL epitope logo
Subtype B
Species (MHC/HLA) human(A*02:01)
Immunogen in vitro stimulation or selection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Tetramer binding
Keywords dendritic cells

Notes

References

Colleton2009 Bonnie A. Colleton, Xiao-Li Huang, Nada M. Melhem, Zheng Fan, Luann Borowski, Giovanna Rappocciolo, and Charles R. Rinaldo. Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells. J. Virol., 83(12):6288-6299, Jun 2009. PubMed ID: 19357176. Show all entries for this paper.


Displaying record number 61317

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HXB2 Location gp160(103-111)
gp120(103-111)
DNA(6531..6557)
gp160 Epitope Map
Author Location  
Epitope QMHEDIISL Epitope Alignment
QMHEDIISL epitope logo
Show epitope variants
Subtype A, B, C, D
Species (MHC/HLA) humanized mouse(A*02:01)
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining, Other
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type modified vaccinia Ankara (MVA), adenovirus
Vaccine strain A clade, B clade, other, C clade

Notes

References

Abdul-Jawad2016 Sultan Abdul-Jawad, Beatrice Ondondo, Andy van Hateren, Andrew Gardner, Tim Elliott, Bette Korber, and Tomáš Hanke. Increased Valency of Conserved-Mosaic Vaccines Enhances the Breadth and Depth of Epitope Recognition. Mol. Ther., 24(2):375-384, Feb 2016. PubMed ID: 26581160. Show all entries for this paper.


Displaying record number 57624

Download this epitope record as JSON.

HXB2 Location gp160(103-111)
gp120(103-111)
DNA(6531..6557)
gp160 Epitope Map
Author Location  
Epitope QMHEDIISL Epitope Alignment
QMHEDIISL epitope logo
Epitope Name QMH
Subtype A, B, C
Species (MHC/HLA) transgenic mouse(A2)
Immunogen vaccine
Experimental methods Flow cytometric T-cell cytokine assay
Keywords epitope processing, vaccine antigen design

Vaccine Details

Vaccine type DNA prime with vaccinia boost, polyepitope
Vaccine strain A clade, B clade, C clade
Vaccine component Env, Gag, Nef, Pol, Vpr

Notes

References

Bazhan2010 S. I. Bazhan, L. I. Karpenko, T. N. Ilyicheva, P. A. Belavin, S. V. Seregin, N. K. Danilyuk, D. V. Antonets, and A. A. Ilyichev. Rational Design Based Synthetic Polyepitope DNA Vaccine for Eliciting HIV-Specific CD8+ T Cell Responses. Mol Immunol, 47(7-8):1507-1515, Apr 2010. PubMed ID: 20189249. Show all entries for this paper.


Displaying record number 57001

Download this epitope record as JSON.

HXB2 Location gp160(103-111)
gp120(103-111)
DNA(6531..6557)
gp160 Epitope Map
Author Location Env
Epitope QMHEDIISL Epitope Alignment
QMHEDIISL epitope logo
Subtype CRF01_AE
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


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