HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 55470

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HXB2 Location Pol(522-530)
RT(367-375)
DNA(3648..3674)
Pol Epitope Map
Author Location Pol
Epitope QLTEAVQKI Epitope Alignment
QLTEAVQKI epitope logo
Subtype B, C
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


Displaying record number 58073

Download this epitope record as JSON.

HXB2 Location Pol(522-530)
RT(367-375)
DNA(3648..3674)
Pol Epitope Map
Author Location Pol
Epitope QLTEAVQKI Epitope Alignment
QLTEAVQKI epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen vaccine
Patient MHC/HLA A*24:02, A*30:01, B*13:02, B*39:01, C*06:02, C*12:03; A*02:01, A*03:01, B*13:02, B*15:01, C*03:04, C*06:02
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type adenovirus type 5 (Ad5), DNA prime with Ad5 boost
Vaccine strain B clade IIIB, B clade JRFL, B clade CAM-1
Vaccine component Gag, Nef, Pol

Notes

References

Li2011a Fusheng Li, Adam C. Finnefrock, Sheri A. Dubey, Bette T. M. Korber, James Szinger, Suzanne Cole, M. Juliana McElrath, John W. Shiver, Danilo R. Casimiro, Lawrence Corey, and Steven G Self. Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias Towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study. PLoS One, 6(6):e20479, 2011. PubMed ID: 21695251. Show all entries for this paper.


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