HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 7 matching records:

Displaying record number 62160

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HXB2 Location Pol(424-432)
RT(269-277)
DNA(3354..3380)
Pol Epitope Map
Author Location RT(269-277)
Epitope QIYPGIKVK Epitope Alignment
QIYPGIKVK epitope logo
Show epitope variants
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Country Australia, Canada, United States
Experimental methods Other
Keywords escape, HLA associated polymorphism

Notes

References

Avila-Rios2009 Santiago Avila-Rios, Christopher E. Ormsby, Jonathan M. Carlson, Humberto Valenzuela-Ponce, Juan Blanco-Heredia, Daniela Garrido-Rodriguez, Claudia Garcia-Morales, David Heckerman, Zabrina L. Brumme, Simon Mallal, Mina John, Enrique Espinosa, and Gustavo Reyes-Teran. Unique Features of HLA-Mediated HIV Evolution in a Mexican Cohort: A Comparative Study. Retrovirology, 6:72, 2009. PubMed ID: 19664284. Show all entries for this paper.


Displaying record number 61135

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HXB2 Location Pol(424-432)
RT(269-277)
DNA(3354..3380)
Pol Epitope Map
Author Location Pol
Epitope QIYPGIKVK Epitope Alignment
QIYPGIKVK epitope logo
Epitope Name QPK9
Subtype C
Species (MHC/HLA) human(A*03:01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining, Other
Keywords escape, mutation acquisition

Notes

References

Carlson2016 Jonathan M. Carlson, Victor Y. Du, Nico Pfeifer, Anju Bansal, Vincent Y. F. Tan, Karen Power, Chanson J. Brumme, Anat Kreimer, Charles E. DeZiel, Nicolo Fusi, Malinda Schaefer, Mark A. Brockman, Jill Gilmour, Matt A. Price, William Kilembe, Richard Haubrich, Mina John, Simon Mallal, Roger Shapiro, John Frater, P. Richard Harrigan, Thumbi Ndung'u, Susan Allen, David Heckerman, John Sidney, Todd M. Allen, Philip J. R. Goulder, Zabrina L. Brumme, Eric Hunter, and Paul A. Goepfert. Impact of Pre-Adapted HIV Transmission. Nat. Med., 22(6):606-613, Jun 2016. PubMed ID: 27183217. Show all entries for this paper.


Displaying record number 61174

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HXB2 Location Pol(424-432)
RT(269-277)
DNA(3354..3380)
Pol Epitope Map
Author Location Pol(424-432)
Epitope QIYPGIKVK Epitope Alignment
QIYPGIKVK epitope logo
Show epitope variants
Epitope Name QPK9
Subtype B
Species (MHC/HLA) human(A*03:01)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords acute/early infection, variant cross-reactivity

Notes

References

Du2016 Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, and Paul A. Goepfert. HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection. J. Immunol., 196(8):3276-3286, 15 Apr 2016. PubMed ID: 26983786. Show all entries for this paper.


Displaying record number 53504

Download this epitope record as JSON.

HXB2 Location Pol(424-432)
RT(269-277)
DNA(3354..3380)
Pol Epitope Map
Author Location Pol
Epitope QIYPGIKVK Epitope Alignment
QIYPGIKVK epitope logo
Epitope Name QK9
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A1, A3, B57, B7, Cw6, Cw7
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, escape, characterizing CD8+ T cells, viral fitness and reversion

Notes

References

Allen2005a Todd M. Allen, Marcus Altfeld, Shaun C. Geer, Elizabeth T. Kalife, Corey Moore, Kristin M. O'Sullivan, Ivna DeSouza, Margaret E. Feeney, Robert L. Eldridge, Erica L. Maier, Daniel E. Kaufmann, Matthew P. Lahaie, Laura Reyor, Giancarlo Tanzi, Mary N. Johnston, Christian Brander, Rika Draenert, Jurgen K. Rockstroh, Heiko Jessen, Eric S. Rosenberg, Simon A. Mallal, and Bruce D. Walker. Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution. J. Virol., 79(21):13239-13249, Nov 2005. PubMed ID: 16227247. Show all entries for this paper.


Displaying record number 62162

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HXB2 Location Pol(424-432)
RT(269-277)
DNA(3354..3380)
Pol Epitope Map
Author Location RT(269-277)
Epitope QIYPGIKVK Epitope Alignment
QIYPGIKVK epitope logo
Show epitope variants
Species (MHC/HLA) human(B*08, B*42)
Immunogen HIV-1 infection
Country Australia, Canada, United States
Experimental methods Other
Keywords escape, HLA associated polymorphism

Notes

References

Avila-Rios2009 Santiago Avila-Rios, Christopher E. Ormsby, Jonathan M. Carlson, Humberto Valenzuela-Ponce, Juan Blanco-Heredia, Daniela Garrido-Rodriguez, Claudia Garcia-Morales, David Heckerman, Zabrina L. Brumme, Simon Mallal, Mina John, Enrique Espinosa, and Gustavo Reyes-Teran. Unique Features of HLA-Mediated HIV Evolution in a Mexican Cohort: A Comparative Study. Retrovirology, 6:72, 2009. PubMed ID: 19664284. Show all entries for this paper.


Displaying record number 57000

Download this epitope record as JSON.

HXB2 Location Pol(424-432)
RT(269-277)
DNA(3354..3380)
Pol Epitope Map
Author Location Pol
Epitope QIYPGIKVK Epitope Alignment
QIYPGIKVK epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


Displaying record number 61102

Download this epitope record as JSON.

HXB2 Location Pol(424-432)
RT(269-277)
DNA(3354..3380)
Pol Epitope Map
Author Location RT(269-277)
Epitope QIYPGIKVK Epitope Alignment
QIYPGIKVK epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA CH470: A*01:01, A*03:01, B*08:01, B*49:01, C*07:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords computational epitope prediction, escape, acute/early infection, mutation acquisition

Notes

References

Barton2016 John P. Barton, Nilu Goonetilleke, Thomas C. Butler, Bruce D. Walker, Andrew J. McMichael, and Arup K. Chakraborty. Relative Rate and Location of Intra-Host HIV Evolution to Evade Cellular Immunity Are Predictable. Nat. Commun., 7:11660, 23 May 2016. PubMed ID: 27212475. Show all entries for this paper.


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