HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 12 matching records:

Displaying record number 60062

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location Pol(675-683)
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Epitope Name QKK9
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60061

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location Pol(675-683)
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Epitope Name QKK9
Species (MHC/HLA) human(A*11)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 53560

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location Pol(676-684)
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Subtype B
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Patient MHC/HLA A11, A2, B18, B44, Cw12, Cw5
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Allen2005a Todd M. Allen, Marcus Altfeld, Shaun C. Geer, Elizabeth T. Kalife, Corey Moore, Kristin M. O'Sullivan, Ivna DeSouza, Margaret E. Feeney, Robert L. Eldridge, Erica L. Maier, Daniel E. Kaufmann, Matthew P. Lahaie, Laura Reyor, Giancarlo Tanzi, Mary N. Johnston, Christian Brander, Rika Draenert, Jurgen K. Rockstroh, Heiko Jessen, Eric S. Rosenberg, Simon A. Mallal, and Bruce D. Walker. Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution. J. Virol., 79(21):13239-13249, Nov 2005. PubMed ID: 16227247. Show all entries for this paper.


Displaying record number 55925

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location RT
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Epitope Name QK9(RT)
Subtype B
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 53482

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location Pol(676-684)
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Epitope Name QK9
Subtype B
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Patient MHC/HLA A11, A2, B18, B44, Cw12, Cw5
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords  

Notes

References

Allen2005 Todd M. Allen, Xu G. Yu, Elizabeth T. Kalife, Laura L. Reyor, Mathias Lichterfeld, Mina John, Michael Cheng, Rachel L. Allgaier, Stanley Mui, Nicole Frahm, Galit Alter, Nancy V. Brown, Mary N. Johnston, Eric S. Rosenberg, Simon A. Mallal, Christian Brander, Bruce D. Walker, and Marcus Altfeld. De Novo Generation of Escape Variant-Specific CD8+ T-Cell Responses Following Cytotoxic T-Lymphocyte Escape in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(20):12952-12960, Oct 2005. PubMed ID: 16188997. Show all entries for this paper.


Displaying record number 60985

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location RT(520-528)
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Subtype B
Species (MHC/HLA) human(A*1101)
Immunogen HIV-1 infection
Patient MHC/HLA 51314: A*0301, A*1101, B*3503, B*5301, Cw*0401, Cw*0401
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 52102

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location Pol(675-683)
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Show epitope variants
Subtype B, CRF01_AE
Species (MHC/HLA) human(A*1101)
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons, TCR usage

Notes

References

Fukada2002 Katsuhiko Fukada, Hiroko Tomiyama, Chantapong Wasi, Tomoko Matsuda, Shigeru Kusagawa, Hironori Sato, Shinichi Oka, Yutaka Takebe, and Masafumi Takiguchi. Cytotoxic T-cell Recognition of HIV-1 Cross-Clade and Clade-Specific Epitopes in HIV-1-Infected Thai and Japanese Patients. AIDS, 16(5):701-711, 29 Mar 2002. PubMed ID: 11964526. Show all entries for this paper.


Displaying record number 52533

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location RT(80-88)
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Species (MHC/HLA) human(A*1101)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 57645

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location Pol(675-)
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Epitope Name Pol675
Subtype B
Species (MHC/HLA) human(A*1101)
Immunogen HIV-1 infection
Country Japan
Experimental methods HLA binding, Intracellular cytokine staining, Relative replication capacity assay, Tetramer binding
Keywords rate of progression

Notes

References

Koizumi2010 Hirokazu Koizumi, Masao Hashimoto, Mamoru Fujiwara, Hayato Murakoshi, Takayuki Chikata, Mohamed Ali Borghan, Atsuko Hachiya, Yuka Kawashima, Hiroshi Takata, Takamasa Ueno, Shinichi Oka, and Masafumi Takiguchi. Different In Vivo Effects of HIV-1 Immunodominant Epitope-Specific Cytotoxic T Lymphocytes on Selection of Escape Mutant Viruses. J. Virol., 84(11):5508-5519, Jun 2010. PubMed ID: 20335254. Show all entries for this paper.


Displaying record number 1194

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location Pol(520-528 LAI)
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Subtype B
Species (MHC/HLA) human(A*1101)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Fukada1999 K. Fukada, Y. Chujoh, H. Tomiyama, K. Miwa, Y. Kaneko, S. Oka, and M. Takiguchi. HLA-A*1101-Restricted Cytotoxic T Lymphocyte Recognition of HIV-1 Pol Protein. AIDS, 13:1413-1414, 1999. PubMed ID: 10449296. Show all entries for this paper.

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 52897

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location Pol
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Epitope Name 1336
Subtype multiple
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A23, A3, B49, B57
Experimental methods T-cell Elispot
Keywords binding affinity, computational epitope prediction

Notes

References

DeGroot2003 Anne S. De Groot, Bill Jesdale, William Martin, Caitlin Saint Aubin, Hakima Sbai, Andrew Bosma, Judy Lieberman, Gail Skowron, Fadi Mansourati, and Kenneth H. Mayer. Mapping Cross-Clade HIV-1 Vaccine Epitopes Using a Bioinformatics Approach. Vaccine, 21(27-30):4486-4504, 1 Oct 2003. PubMed ID: 14505932. Show all entries for this paper.


Displaying record number 56999

HXB2 Location Pol(675-683)
RT(520-528)
DNA(4107..4133)
Pol Epitope Map
Author Location Pol
Epitope QIIEQLIKK Epitope Alignment
QIIEQLIKK epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


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