HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 4 matching records:

Displaying record number 59292

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HXB2 Location gp160(352-361)
gp120(352-361)
DNA(7278..7307)
gp160 Epitope Map
Author Location Env(352-360)
Epitope QFRNKTIVF Epitope Alignment
QFRNKTIVF epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Patient MHC/HLA CH077: A*02:05, B*53:01, B*57:01, C*04:01, C*18:01
Experimental methods CD8 T-cell Elispot - IFNγ, Relative replication capacity assay
Keywords viral fitness and reversion

Notes

References

Song2014 Hongshuo Song, Bhavna Hora, Tanmoy Bhattacharya, Nilu Goonetilleke, Michael K. P. Liu, Kevin Wiehe, Hui Li, Shilpa S. Iyer, Andrew J. McMichael, Alan S. Perelson, and Feng Gao. Reversion and T Cell Escape Mutations Compensate the Fitness Loss of a CD8+ T Cell Escape Mutant in Their Cognate Transmitted/Founder Virus. PLoS One, 9(7):e102734, 2014. PubMed ID: 25028937. Show all entries for this paper.


Displaying record number 57473

Download this epitope record as JSON.

HXB2 Location gp160(352-361)
gp120(352-361)
DNA(7278..7307)
gp160 Epitope Map
Author Location Env
Epitope QFRNKTIVF Epitope Alignment
QFRNKTIVF epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(C*04:01)
Immunogen HIV-1 infection
Patient MHC/HLA A*02:05, A*02:05, B*53:01, B*57:01, C*04:01, C*18:01
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords acute/early infection

Notes

References

Wood2009 Natasha Wood, Tanmoy Bhattacharya, Brandon F. Keele, Elena Giorgi, Michael Liu, Brian Gaschen, Marcus Daniels, Guido Ferrari, Barton F. Haynes, Andrew McMichael, George M. Shaw, Beatrice H. Hahn, Bette Korber, and Cathal Seoighe. HIV Evolution in Early Infection: Selection Pressures, Patterns of Insertion and Deletion, and the Impact of APOBEC. PLoS Pathog., 5(5):e1000414, May 2009. PubMed ID: 19424423. Show all entries for this paper.


Displaying record number 58238

Download this epitope record as JSON.

HXB2 Location gp160(352-361)
gp120(352-361)
DNA(7278..7307)
gp160 Epitope Map
Author Location Env(358-366)
Epitope QFRNKTIVF Epitope Alignment
QFRNKTIVF epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(C*04:01)
Immunogen HIV-1 infection
Patient MHC/HLA CH077: A*02:05, B*53:01, B*57:01, C*04:01, C*18:01
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords dynamics, escape, acute/early infection, autologous responses, characterizing CD8+ T cells

Notes

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 56642

Download this epitope record as JSON.

HXB2 Location gp160(352-361)
gp120(352-361)
DNA(7278..7307)
gp160 Epitope Map
Author Location Env(352-360)
Epitope QFRNKTIVF Epitope Alignment
QFRNKTIVF epitope logo
Show epitope variants
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA A*02:05, B*53:01, B*57:01, C*04:01, C*18:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords escape, acute/early infection

Notes

References

Goonetilleke2009 Nilu Goonetilleke, Michael K. P. Liu, Jesus F. Salazar-Gonzalez, Guido Ferrari, Elena Giorgi, Vitaly V. Ganusov, Brandon F. Keele, Gerald H. Learn, Emma L. Turnbull, Maria G Salazar, Kent J Weinhold, Stephen Moore, CHAVI Clinical Core B, Norman Letvin, Barton F. Haynes, Myron S. Cohen, Peter Hraber, Tanmoy Bhattacharya, Persephone Borrow, Alan S. Perelson, Beatrice H. Hahn, George M. Shaw, Bette T. Korber, and Andrew J. McMichael. The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. J. Exp. Med., 206(6):1253-1272, 8 Jun 2009. PubMed ID: 19487423. Show all entries for this paper.


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