HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 11 matching records:

Displaying record number 60059

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HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location Env(805-814)
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Epitope Name QL10
Species (MHC/HLA) human(B*08)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60981

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HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location gp160(805-814)
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Subtype B
Species (MHC/HLA) human(B*08:01)
Immunogen HIV-1 infection
Patient MHC/HLA 67200: A*01:01, A*24:02, B*08:01, B*57:01, C*06:02, C*07:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 60060

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HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location Env(805-814)
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Epitope Name QL10
Species (MHC/HLA) human(B*35:02, B*35:03, B*53:01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60058

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HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location Env(805-814)
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Epitope Name QL10
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 56039

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HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location gp41
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Epitope Name QL10(gp41)
Subtype B
Species (MHC/HLA) human(B40)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 60982

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HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location gp160(805-814)
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Subtype B
Species (MHC/HLA) human(B*40:01)
Immunogen HIV-1 infection
Patient MHC/HLA 98621: A*02:01:01G, B*40:01:01G, B*44:02:01G, C*03:04:01G, C*05:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection

Notes

References

Kunwar2013 Pratima Kunwar, Natalie Hawkins, Warren L. Dinges, Yi Liu, Erin E. Gabriel, David A. Swan, Claire E. Stevens, Janine Maenza, Ann C. Collier, James I. Mullins, Tomer Hertz, Xuesong Yu, and Helen Horton. Superior Control of HIV-1 Replication by CD8+ T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design. PLoS One, 8(5):e64405, 2013. PubMed ID: 23741326. Show all entries for this paper.


Displaying record number 55062

Download this epitope record as JSON.

HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location Env(805-814)
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Show epitope variants
Epitope Name QL10
Species (MHC/HLA) human(B*40:01)
Immunogen HIV-1 infection
Patient MHC/HLA A*02:01, A*24:02, B*40:01, B*50:01, C*03, Cw4
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords immunodominance, escape, variant cross-reactivity

Notes

References

Draenert2006 Rika Draenert, Todd M. Allen, Yang Liu, Terri Wrin, Colombe Chappey, Cori L. Verrill, Guillem Sirera, Robert L. Eldridge, Matthew P. Lahaie, Lidia Ruiz, Bonaventura Clotet, Christos J. Petropoulos, Bruce D. Walker, and Javier Martinez-Picado. Constraints on HIV-1 Evolution and Immunodominance Revealed in Monozygotic Adult Twins Infected with the Same Virus. J. Exp. Med., 203(3):529-539, 20 Mar 2006. PubMed ID: 16533886. Show all entries for this paper.


Displaying record number 874

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HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location gp41(810-819 LAI)
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Subtype B
Species (MHC/HLA) human(B*40:01)
Immunogen  
Experimental methods  
Keywords optimal epitope, A-list

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 1812

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HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location gp41(805-814)
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Species (MHC/HLA) human(B*60, B*61)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.


Displaying record number 1843

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HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location gp41( SF2)
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Species (MHC/HLA) human(B60)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Altfeld2000 M. A. Altfeld, A. Trocha, R. L. Eldridge, E. S. Rosenberg, M. N. Phillips, M. M. Addo, R. P. Sekaly, S. A. Kalams, S. A. Burchett, K. McIntosh, B. D. Walker, and P. J. Goulder. Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay. J. Virol., 74:8541, 2000. PubMed ID: 10954555. Show all entries for this paper.


Displaying record number 52220

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HXB2 Location gp160(805-814)
gp41(294-303)
DNA(8637..8666)
gp160 Epitope Map
Author Location Env(799-813 BH10, LAI)
Epitope QELKNSAVSL Epitope Alignment
QELKNSAVSL epitope logo
Species (MHC/HLA) human
Immunogen computer prediction
Experimental methods Other
Keywords computational epitope prediction, T-cell crossreactivity to human proteins

Notes

References

Maksiutov2002 A. Z. Maksiutov, A. G. Bachinskii, and S. I. Bazhan. [Searching for Local Similarities Between HIV-1 and Human Proteins. Application to Vaccines]. Mol Biol (Mosk), 36(3):447-459, May-Jun 2002. Article in Russian. PubMed ID: 12068630. Show all entries for this paper.


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