HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 1074

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HXB2 Location Nef(136-145)
DNA(9202..9231)
Nef Epitope Map
Author Location Nef(157-166)
Epitope PLTFGWCFKL Epitope Alignment
PLTFGWCFKL epitope logo
Species (MHC/HLA) human(A*02)
Immunogen vaccine
Experimental methods  
Keywords  

Vaccine Details

Vaccine type DNA prime with vaccinia boost

Notes

References

Woodberry1999 T. Woodberry, J. Gardner, L. Mateo, D. Eisen, J. Medveczky, I. A. Ramshaw, S. A. Thomson, R. A. Ffrench, S. L. Elliott, H. Firat, F. A. Lemonnier, and A. Suhrbier. Immunogenicity of a Human Immunodeficiency Virus (HIV) Polytope Vaccine. J. Virol., 73:5320-5325, 1999. PubMed ID: 10364278. Show all entries for this paper.


Displaying record number 53800

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HXB2 Location Nef(136-145)
DNA(9202..9231)
Nef Epitope Map
Author Location Nef
Epitope PLTFGWCFKL Epitope Alignment
PLTFGWCFKL epitope logo
Epitope Name P10L
Species (MHC/HLA) transgenic mouse(A*02:01)
Immunogen vaccine
Experimental methods Chromium-release assay, Flow cytometric T-cell cytokine assay
Keywords memory cells, vaccine antigen design, characterizing CD8+ T cells

Vaccine Details

Vaccine type measles virus (MV)
Vaccine strain multiple epitope immunogen
Vaccine component gp140, gp140ΔV3

Notes

References

Lorin2005a Clarisse Lorin, Frédéric Delebecque, Valérie Labrousse, Lucie Da Silva, François Lemonnier, Michel Brahic, and Frédéric Tangy. A Recombinant Live Attenuated Measles Vaccine Vector Primes Effective HLA-A0201-Restricted Cytotoxic T Lymphocytes and Broadly Neutralizing Antibodies against HIV-1 Conserved Epitopes. Vaccine, 23(36):4463-4472, 22 Aug 2005. PubMed ID: 15993518. Show all entries for this paper.


Displaying record number 1073

Download this epitope record as JSON.

HXB2 Location Nef(136-145)
DNA(9202..9231)
Nef Epitope Map
Author Location Nef(136-145)
Epitope PLTFGWCFKL Epitope Alignment
PLTFGWCFKL epitope logo
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons

Notes

References

Durali1998 D. Durali, J. Morvan, F. Letourneur, D. Schmitt, N. Guegan, M. Dalod, S. Saragosti, D. Sicard, J. P. Levy, and E. Gomard. Cross-Reactions between the Cytotoxic T-Lymphocyte Responses of Human Immunodeficiency Virus-Infected African and European Patients. J. Virol., 72:3547-3553, 1998. PubMed ID: 9557634. Show all entries for this paper.


Displaying record number 55902

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HXB2 Location Nef(136-145)
DNA(9202..9231)
Nef Epitope Map
Author Location Nef
Epitope PLTFGWCFKL Epitope Alignment
PLTFGWCFKL epitope logo
Show epitope variants
Epitope Name PL11(Nef)
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords variant cross-reactivity, chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 59262

Download this epitope record as JSON.

HXB2 Location Nef(136-145)
DNA(9202..9231)
Nef Epitope Map
Author Location Nef(136-145)
Epitope PLTFGWCFKL Epitope Alignment
PLTFGWCFKL epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA Subject 8: A*02:01, A*24:02, B*07:02, B*40:01, C*03:04, C*07:02
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords dynamics, acute/early infection, dendritic cells

Notes

References

Melhem2014 Nada M Melhem, Kellie N. Smith, Xiao-Li Huang, Bonnie A Colleton, Weimin Jiang, Robbie B. Mailliard, James I. Mullins, and Charles R. Rinaldo. The Impact of Viral Evolution and Frequency of Variant Epitopes on Primary and Memory Human Immunodeficiency Virus Type 1-Specific CD8+ T Cell Responses. Virology, 450-451:34-48, Feb 2014. PubMed ID: 24503065. Show all entries for this paper.


Displaying record number 61663

Download this epitope record as JSON.

HXB2 Location Nef(136-145)
DNA(9202..9231)
Nef Epitope Map
Author Location Nef(136-145)
Epitope PLTFGWCFKL Epitope Alignment
PLTFGWCFKL epitope logo
Epitope Name PL10
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA AC1: A*02:01, A*30:01, B*37:01, B*38:01, C*06:02, C*12:03; VP1: A*02:01, A*03:01, B*41:01, B*52:01, C*03:03, C*17:01
Country United States
Experimental methods Other, Relative replication capacity assay
Keywords NK cells, transmission pair

Notes

References

Walker-Sperling2017 Victoria E. Walker-Sperling, Christopher W. Pohlmeyer, Rebecca T. Veenhuis, Megan May, Krystle A. Luna, Allison R. Kirkpatrick, Oliver Laeyendecker, Andrea L. Cox, Mary Carrington, Justin R. Bailey, Roberto C. Arduino, and Joel N. Blankson. Factors Associated with the Control of Viral Replication and Virologic Breakthrough in a Recently Infected HIV-1 Controller. EBioMedicine, 16:141-149, Feb 2017. PubMed ID: 28159573. Show all entries for this paper.


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