HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 16 matching records:

Displaying record number 60035

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location Pol(547-556)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Epitope Name PW10
Species (MHC/HLA) human(A*24)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60037

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location Pol(547-556)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Epitope Name PW10
Species (MHC/HLA) human(A*25)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60036

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location Pol(547-556)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Epitope Name PW10
Species (MHC/HLA) human(A*29)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60034

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location Pol(547-556)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Epitope Name PW10
Species (MHC/HLA) human(A*32)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 57150

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location RT(392-401)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Epitope Name PW10
Subtype B
Species (MHC/HLA) human(A32)
Immunogen HIV-1 infection
Patient MHC/HLA A26, A32, B27, Cw1, Cw2
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HIV exposed persistently seronegative (HEPS), acute/early infection

Notes

References

Liu2009b Yi Liu, Amanda Woodward, Haiying Zhu, Thomas Andrus, John McNevin, Jean Lee, James I. Mullins, Lawrence Corey, M. Juliana McElrath, and Tuofu Zhu. Preinfection Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T Lymphocytes Failed to Prevent HIV Type 1 Infection from Strains Genetically Unrelated to Viruses in Long-Term Exposed Partners. J. Virol., 83(20):10821-10829, Oct 2009. PubMed ID: 19706711. Show all entries for this paper.


Displaying record number 1533

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location RT(559-568 SF2)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Species (MHC/HLA) human(A32)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.


Displaying record number 52276

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location RT
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Epitope Name A32-PW10(RT)
Subtype B
Species (MHC/HLA) human(A32)
Immunogen HIV-1 infection
Patient MHC/HLA A32, B14, B7; A32, B44; A30, A32, B18, B27
Experimental methods  
Keywords HAART, ART, supervised treatment interruptions (STI)

Notes

References

Altfeld2002 Marcus Altfeld, Jan van Lunzen, Nicole Frahm, Xu G. Yu, Claus Schneider, Robert L. Eldridge, Margaret E. Feeney, Dirk Meyer-Olson, Hans-Juergen Stellbrink, and Bruce D. Walker. Expansion of Pre-existing, Lymph Node-localized CD8+ T Cells During Supervised Treatment Interruptions in Chronic HIV-1 Infection. J. Clin. Invest., 109(6):837-843, Mar 2002. PubMed ID: 11901192. Show all entries for this paper.


Displaying record number 55028

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location  
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Species (MHC/HLA) human(A32)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding
Keywords binding affinity, immunodominance, optimal epitope

Notes

References

Bihl2006 Florian Bihl, Nicole Frahm, Loriana Di Giammarino, John Sidney, Mina John, Karina Yusim, Tonia Woodberry, Kaori Sango, Hannah S. Hewitt, Leah Henry, Caitlyn H. Linde, John V. Chisholm, III, Tauheed M. Zaman, Eunice Pae, Simon Mallal, Bruce D Walker, Alessandro Sette, Bette T. Korber, David Heckerman, and Christian Brander. Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses. J. Immunol., 176(7):4094-4101, 1 Apr 2006. PubMed ID: 16547245. Show all entries for this paper.


Displaying record number 55207

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location  
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Species (MHC/HLA) human(A32)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords supertype, HLA cross-presentation

Notes

References

Frahm2007b Nicole Frahm, Karina Yusim, Todd J. Suscovich, Sharon Adams, John Sidney, Peter Hraber, Hannah S. Hewitt, Caitlyn H. Linde, Daniel G. Kavanagh, Tonia Woodberry, Leah M. Henry, Kellie Faircloth, Jennifer Listgarten, Carl Kadie, Nebojsa Jojic, Kaori Sango, Nancy V. Brown, Eunice Pae, M. Tauheed Zaman, Florian Bihl, Ashok Khatri, Mina John, Simon Mallal, Francesco M. Marincola, Bruce D . Walker, Alessandro Sette, David Heckerman, Bette T. Korber, and Christian Brander. Extensive HLA Class I Allele Promiscuity among Viral CTL Epitopes. Eur. J. Immunol., 37(9):2419-2433, Sep 2007. PubMed ID: 17705138. Show all entries for this paper.


Displaying record number 551

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location RT(559-568 LAI)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(A*3201)
Immunogen  
Experimental methods  
Keywords  

Notes

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.


Displaying record number 1134

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location RT(559-568 LAI)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Subtype B
Species (MHC/HLA) human(A*3201)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy CedeƱo, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 1979

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location RT(392-401)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Epitope Name Pol-PW10; RT-PW10
Subtype B
Species (MHC/HLA) human(A*3201)
Immunogen HIV-1 infection
Patient MHC/HLA 01RCH59: A*0201, A*3201, B*4002, B*5301, Cw*0202, Cw*0401
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords  

Notes

References

Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.


Displaying record number 58797

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location RT(559-568)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Species (MHC/HLA) human(A*3201)
Immunogen  
Experimental methods  
Keywords review

Notes

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.


Displaying record number 60039

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location Pol(547-556)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Epitope Name PW10
Species (MHC/HLA) human(B*1517)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60038

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location Pol(547-556)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Epitope Name PW10
Species (MHC/HLA) human(B*3501, B*3508)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60040

HXB2 Location Pol(547-556)
RT(392-401)
DNA(3723..3752)
Pol Epitope Map
Author Location Pol(547-556)
Epitope PIQKETWETW Epitope Alignment
PIQKETWETW epitope logo
Epitope Name PW10
Species (MHC/HLA) human(C*06)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


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