HIV molecular immunology database


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Displaying record number 1049

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HXB2 Location Nef(126-138)
Nef Epitope Map
Author Location Nef(126-138 BRU)
Epitope NYTPGPGVRYPLT Epitope Alignment
NYTPGPGVRYPLT epitope logo
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods  



Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.

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