HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 52866

Download this epitope record as JSON.

HXB2 Location Pol(212-221)
RT(57-66)
DNA(2718..2747)
Pol Epitope Map
Author Location Pol
Epitope NTPVFAIKKK Epitope Alignment
NTPVFAIKKK epitope logo
Epitope Name 1274
Subtype multiple
Species (MHC/HLA) human(A11, A68, B8)
Immunogen HIV-1 infection
Patient MHC/HLA 202001: A25, A68, B18, B27; 606001: A1, A68, B15, B40, Cw3
Country United States
Experimental methods T-cell Elispot
Keywords binding affinity, supertype, computational epitope prediction, immunodominance, HLA cross-presentation, novel epitope

Notes

References

DeGroot2003 Anne S. De Groot, Bill Jesdale, William Martin, Caitlin Saint Aubin, Hakima Sbai, Andrew Bosma, Judy Lieberman, Gail Skowron, Fadi Mansourati, and Kenneth H. Mayer. Mapping Cross-Clade HIV-1 Vaccine Epitopes Using a Bioinformatics Approach. Vaccine, 21(27-30):4486-4504, 1 Oct 2003. PubMed ID: 14505932. Show all entries for this paper.


Displaying record number 54968

Download this epitope record as JSON.

HXB2 Location Pol(212-221)
RT(57-66)
DNA(2718..2747)
Pol Epitope Map
Author Location Pol(209-221)
Epitope NTPVFAIKKK Epitope Alignment
NTPVFAIKKK epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection, peptide-HLA interaction
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords immunodominance, T-cell crossreactivity to human proteins

Notes

References

Rolland2007a Morgane Rolland, David C. Nickle, Wenjie Deng, Nicole Frahm, Christian Brander, Gerald H. Learn, David Heckerman, Nebosja Jojic, Vladimir Jojic, Bruce D. Walker, and James I. Mullins. Recognition of HIV-1 Peptides by Host CTL Is Related to HIV-1 Similarity to Human Proteins. PLoS ONE, 2(9):e823, 2007. PubMed ID: 17786195. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health