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Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 58600

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HXB2 Location Gag(253-262)
p24(121-130)
DNA(1546..1575)
Gag Epitope Map
Author Location Gag(253-262)
Epitope NPPIPVGDIY Epitope Alignment
NPPIPVGDIY epitope logo
Show epitope variants
Epitope Name NY10, NY10-260D
Subtype C
Species (MHC/HLA) human(B*35:01)
Immunogen HIV-1 infection
Country Barbados, Botswana, Haiti, Japan, Mexico, South Africa, United Kingdom, United States
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining, Tetramer binding
Keywords subtype comparisons, optimal epitope

Notes

References

Matthews2012 Philippa C. Matthews, Madoka Koyanagi, Henrik N. Kløverpris, Mikkel Harndahl, Anette Stryhn, Tomohiro Akahoshi, Hiroyuki Gatanaga, Shinichi Oka, Claudia Juarez Molina, Humberto Valenzuela Ponce, Santiago Avila Rios, David Cole, Jonathan Carlson, Rebecca P. Payne, Anthony Ogwu, Alfred Bere, Thumbi Ndung'u, Kamini Gounder, Fabian Chen, Lynn Riddell, Graz Luzzi, Roger Shapiro, Christian Brander, Bruce Walker, Andrew K. Sewell, Gustavo Reyes Teran, David Heckerman, Eric Hunter, Søren Buus, Masafumi Takiguchi, and Philip J. R. Goulder. Differential Clade-Specific HLA-B*3501 Association with HIV-1 Disease Outcome Is Linked to Immunogenicity of a Single Gag Epitope. J. Virol., 86(23):12643-12654, Dec 2012. PubMed ID: 22973023. Show all entries for this paper.


Displaying record number 58627

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HXB2 Location Gag(253-262)
p24(121-130)
DNA(1546..1575)
Gag Epitope Map
Author Location  
Epitope NPPIPVGDIY Epitope Alignment
NPPIPVGDIY epitope logo
Species (MHC/HLA) human(B*35:01)
Immunogen  
Experimental methods  
Keywords optimal epitope, A-list

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 61211

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HXB2 Location Gag(253-262)
p24(121-130)
DNA(1546..1575)
Gag Epitope Map
Author Location Gag(254-262)
Epitope NPPIPVGDIY Epitope Alignment
NPPIPVGDIY epitope logo
Show epitope variants
Epitope Name NY10
Subtype B
Species (MHC/HLA) human(B*35:01)
Immunogen HIV-1 infection
Experimental methods Other
Keywords review, escape, HLA associated polymorphism

Notes

References

Kloverpris2015a Henrik N. Kløverpris, Alasdair Leslie, and Philip Goulder. Role of HLA Adaptation in HIV Evolution. Front. Immunol., 6:665, 18 Jan 2016. PubMed ID: 26834742. Show all entries for this paper.


Displaying record number 59119

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HXB2 Location Gag(253-262)
p24(121-130)
DNA(1546..1575)
Gag Epitope Map
Author Location Gag(253-262)
Epitope NPPIPVGDIY Epitope Alignment
NPPIPVGDIY epitope logo
Show epitope variants
Epitope Name NY10
Subtype CRF01_AE
Species (MHC/HLA) human(B*35:01, B*35:05)
Immunogen HIV-1 infection
Patient MHC/HLA P206: A*02:03, A*11:02, B*18:02, B*35:01, C*04:01, C*07:04; P381: A*11:01, A*33:03, B*15:02, B*35:01, C*04:01, C*08:01; P453: A*24:02, B*15:25, B*35:01, C*07:02, C*12:03; P1349: A*02:03, A*11:01, B*35:01, B*38:02, C*03:03, C*07:02; P2097: A*24:02, A*31:01, B*35:01, B*46:01, C*01:02, C*04:01; P115: A*02:06, A*11:01, B*35:05, B*46:01, C*01:02, C*04:01; P1013: A*02:03, A*11:01, B*35:05, B*52:01, C*04:01, C*07:01; P1497: A*02:01, A*11:01, B*13:01, B*35:05, C*04:01, C*04:06; P1651: A*02:06, A*11:01, B*35:05, B*40:06, C*04:01, C*08:01
Country Thailand
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords structure, HLA associated polymorphism

Notes

References

Mori2014 Masahiko Mori, Nuanjun Wichukchinda, Reiko Miyahara, Archawin Rojanawiwat, Panita Pathipvanich, Tomoyuki Maekawa, Toshiyuki Miura, Philip Goulder, Michio Yasunami, Koya Ariyoshi, and Pathom Sawanpanyalert. HLA-B*35:05 Is a Protective Allele with a Unique Structure among HIV-1 CRF01\_AE-Infected Thais, in Whom the B*57 Frequency Is Low. AIDS, 28(7):959-967, 24 Apr 2014. PubMed ID: 24566094. Show all entries for this paper.


Displaying record number 62805

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HXB2 Location Gag(253-262)
p24(121-130)
DNA(1546..1575)
Gag Epitope Map
Author Location p24(253-262)
Epitope NPPIPVGDIY Epitope Alignment
NPPIPVGDIY epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen engineered
Experimental methods Other, Relative replication capacity assay
Keywords assay or method development, protective allele

Notes

References

Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.


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