HIV molecular immunology database
Found 5 matching records:
Download this epitope record as JSON.
HXB2 Location | Gag(253-262) p24(121-130) DNA(1546..1575) |
Gag Epitope Map |
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Author Location | Gag(253-262) | |
Epitope |
NPPIPVGDIY
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | NY10, NY10-260D | |
Subtype | C | |
Species (MHC/HLA) | human(B*35:01) | |
Immunogen | HIV-1 infection | |
Country | Barbados, Botswana, Haiti, Japan, Mexico, South Africa, United Kingdom, United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining, Tetramer binding | |
Keywords | subtype comparisons, optimal epitope |
Matthews2012 Philippa C. Matthews, Madoka Koyanagi, Henrik N. Kløverpris, Mikkel Harndahl, Anette Stryhn, Tomohiro Akahoshi, Hiroyuki Gatanaga, Shinichi Oka, Claudia Juarez Molina, Humberto Valenzuela Ponce, Santiago Avila Rios, David Cole, Jonathan Carlson, Rebecca P. Payne, Anthony Ogwu, Alfred Bere, Thumbi Ndung'u, Kamini Gounder, Fabian Chen, Lynn Riddell, Graz Luzzi, Roger Shapiro, Christian Brander, Bruce Walker, Andrew K. Sewell, Gustavo Reyes Teran, David Heckerman, Eric Hunter, Søren Buus, Masafumi Takiguchi, and Philip J. R. Goulder. Differential Clade-Specific HLA-B*3501 Association with HIV-1 Disease Outcome Is Linked to Immunogenicity of a Single Gag Epitope. J. Virol., 86(23):12643-12654, Dec 2012. PubMed ID: 22973023. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(253-262) p24(121-130) DNA(1546..1575) |
Gag Epitope Map |
---|---|---|
Author Location | ||
Epitope |
NPPIPVGDIY
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*35:01) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(253-262) p24(121-130) DNA(1546..1575) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(254-262) | |
Epitope |
NPPIPVGDIY
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | NY10 | |
Subtype | B | |
Species (MHC/HLA) | human(B*35:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | Other | |
Keywords | review, escape, HLA associated polymorphism |
Kloverpris2015a Henrik N. Kløverpris, Alasdair Leslie, and Philip Goulder. Role of HLA Adaptation in HIV Evolution. Front. Immunol., 6:665, 18 Jan 2016. PubMed ID: 26834742. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(253-262) p24(121-130) DNA(1546..1575) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(253-262) | |
Epitope |
NPPIPVGDIY
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | NY10 | |
Subtype | CRF01_AE | |
Species (MHC/HLA) | human(B*35:01, B*35:05) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | P206: A*02:03, A*11:02, B*18:02, B*35:01, C*04:01, C*07:04; P381: A*11:01, A*33:03, B*15:02, B*35:01, C*04:01, C*08:01; P453: A*24:02, B*15:25, B*35:01, C*07:02, C*12:03; P1349: A*02:03, A*11:01, B*35:01, B*38:02, C*03:03, C*07:02; P2097: A*24:02, A*31:01, B*35:01, B*46:01, C*01:02, C*04:01; P115: A*02:06, A*11:01, B*35:05, B*46:01, C*01:02, C*04:01; P1013: A*02:03, A*11:01, B*35:05, B*52:01, C*04:01, C*07:01; P1497: A*02:01, A*11:01, B*13:01, B*35:05, C*04:01, C*04:06; P1651: A*02:06, A*11:01, B*35:05, B*40:06, C*04:01, C*08:01 | |
Country | Thailand | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | structure, HLA associated polymorphism |
Mori2014 Masahiko Mori, Nuanjun Wichukchinda, Reiko Miyahara, Archawin Rojanawiwat, Panita Pathipvanich, Tomoyuki Maekawa, Toshiyuki Miura, Philip Goulder, Michio Yasunami, Koya Ariyoshi, and Pathom Sawanpanyalert. HLA-B*35:05 Is a Protective Allele with a Unique Structure among HIV-1 CRF01\_AE-Infected Thais, in Whom the B*57 Frequency Is Low. AIDS, 28(7):959-967, 24 Apr 2014. PubMed ID: 24566094. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(253-262) p24(121-130) DNA(1546..1575) |
Gag Epitope Map |
---|---|---|
Author Location | p24(253-262) | |
Epitope |
NPPIPVGDIY
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | assay or method development, protective allele |
Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.