HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 12 matching records:

Displaying record number 59423

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location Gag
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Subtype B
Species (MHC/HLA) human(B*51)
Immunogen HIV-1 infection
Patient MHC/HLA LTNP/EC-4: A*03, A*11, B*35, B*51, C*04, C*15; CP-1: A*02, A*11, B*08, B*51, C*04, C*07; CP-4: A*02, B*44, B*51, C*05, C*14; SP-4: A*02, A*30, B*44, B*51, C*02, C*05
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, immunodominance

Notes

References

Migueles2015 Stephen A. Migueles, Daniel Mendoza, Matthew G. Zimmerman, Kelly M. Martins, Sushila A. Toulmin, Elizabeth P. Kelly, Bennett A. Peterson, Sarah A. Johnson, Eric Galson, Kate O. Poropatich, Andy Patamawenu, Hiromi Imamichi, Alexander Ober, Catherine A. Rehm, Sara Jones, Claire W. Hallahan, Dean A. Follmann, and Mark Connors. CD8+ T-Cell Cytotoxic Capacity Associated with Human Immunodeficiency Virus-1 Control Can Be Mediated through Various Epitopes and Human Leukocyte Antigen Types. EBioMedicine, 2(1):46-58, Jan 2015. PubMed ID: 26137533. Show all entries for this paper.


Displaying record number 58394

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location Gag(327-335 IIIB, MN)
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Show epitope variants
Epitope Name NI9
Subtype B
Species (MHC/HLA) human(B*51)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ, CTL suppression of replication
Keywords rate of progression, immunodominance, escape, HLA associated polymorphism, elite controllers

Notes

References

Zhang2011 YongHong Zhang, YanChun Peng, HuiPing Yan, Keyi Xu, Masumichi Saito, Hao Wu, XinYue Chen, Srinika Ranasinghe, Nozomi Kuse, Tim Powell, Yan Zhao, WeiHua Li, Xin Zhang, Xia Feng, Ning Li, Aleksandra Leligdowicz, XiaoNing Xu, Mina John, Masafumi Takiguchi, Andrew McMichael, Sarah Rowland-Jones, and Tao Dong. Multilayered Defense in HLA-B51-Associated HIV Viral Control. J. Immunol., 187(2):684-691, 15 Jul 2011. PubMed ID: 21670313. Show all entries for this paper.


Displaying record number 1386

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location p24(323-333)
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Epitope Name NAN
Species (MHC/HLA) human(B51)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART, acute/early infection

Notes

References

Oxenius2000b A. Oxenius, D. A. Price, P. J. Easterbrook, C. A. O'Callaghan, A. D. Kelleher, J. A. Whelan, G. Sontag, A. K. Sewell, and R. E. Phillips. Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes. Proc. Natl. Acad. Sci. U.S.A., 97(7):3382-7, 28 Mar 2000. URL: http://www.pnas.org/cgi/content/full/97/7/3382. PubMed ID: 10737796. Show all entries for this paper.


Displaying record number 52979

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location p24(193-201)
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Species (MHC/HLA) human(B51)
Immunogen HIV-1 infection
Patient MHC/HLA A3, A32, B15, B51, C*03, Cw6, DQ7, DR4, DR8
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, escape

Notes

References

Geels2003 Mark J. Geels, Marion Cornelissen, Hanneke Schuitemaker, Kiersten Anderson, David Kwa, Jolanda Maas, John T. Dekker, Elly Baan, Fokla Zorgdrager, Remco van den Burg, Martijn van Beelen, Vladimir V. Lukashov, Tong-Ming Fu, William A. Paxton, Lia van der Hoek, Sheri A. Dubey, John W. Shiver, and Jaap Goudsmit. Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual. J. Virol., 77(23):12430-12440, Dec 2003. PubMed ID: 14610167. Show all entries for this paper.


Displaying record number 53456

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location p24
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Species (MHC/HLA) human(B51)
Immunogen HIV-1 infection
Patient MHC/HLA A1, A32, B*14:10, B15; A*31:01, A68, B*44:03, B51
Country Spain
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HAART, ART, supervised treatment interruptions (STI)

Notes

References

Arnedo-Valero2004 Mireia Arnedo-Valero, Montserrat Plana, Antonio Mas, Meritxell Guilà, Cristina Gil, Pedro Castro, Felipe Garcia, Esteban Domingo, Josep Ma Gatell, and Tomàs Pumarola. Similar HIV-1 Evolution and Immunological Responses at 10 Years Despite Several Therapeutic Strategies and Host HLA Types. J. Med. Virol., 73(4):495-501, Aug 2004. PubMed ID: 15221891. Show all entries for this paper.


Displaying record number 350

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location p24(324-335 IIIB)
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Species (MHC/HLA) human(B51)
Immunogen HIV-1 infection
Experimental methods  
Keywords responses in children, mother-to-infant transmission, escape

Notes

References

Wilson1999a C. C. Wilson, R. C. Brown, B. T. Korber, B. M. Wilkes, D. J. Ruhl, D. Sakamoto, K. Kunstman, K. Luzuriaga, I. C. Hanson, S. M. Widmayer, A. Wiznia, S. Clapp, A. J. Ammann, R. A. Koup, S. M. Wolinsky, and B. D. Walker. Frequent Detection of Escape from Cytotoxic T-Lymphocyte Recognition in Perinatal Human Immunodeficiency Virus (HIV) Type 1 Transmission: The Ariel Project for the Prevention of Transmission of HIV from Mother to Infant. J. Virol., 73:3975-3985, 1999. PubMed ID: 10196293. Show all entries for this paper.


Displaying record number 349

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location Gag(327-335 SF2)
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Show epitope variants
Species (MHC/HLA) human(B*51:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons, rate of progression

Notes

References

Tomiyama1999 H. Tomiyama, T. Sakaguchi, K. Miwa, S. Oka, A. Iwamoto, Y. Kaneko, and M. Takiguchi. Identification of multiple HIV-1 CTL epitopes presented by HLA-B*5101. Hum. Immunol., 60:177-86, 1999. PubMed ID: 10321954. Show all entries for this paper.


Displaying record number 57642

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location Gag(327-329)
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Epitope Name Gag327-9
Subtype B
Species (MHC/HLA) human(B*51:01)
Immunogen HIV-1 infection
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay
Keywords rate of progression

Notes

References

Kawashima2010 Yuka Kawashima, Nozomi Kuse, Hiroyuki Gatanaga, Takuya Naruto, Mamoru Fujiwara, Sachi Dohki, Tomohiro Akahoshi, Katsumi Maenaka, Philip Goulder, Shinichi Oka, and Masafumi Takiguchi. Long-Term Control of HIV-1 in Hemophiliacs Carrying Slow-Progressing Allele HLA-B*5101. J. Virol., 84(14):7151-7160, Jul 2010. PubMed ID: 20410273. Show all entries for this paper.


Displaying record number 53159

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location p24(193-201)
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Show epitope variants
Species (MHC/HLA) human(B*51:01)
Immunogen HIV-1 infection
Patient MHC/HLA A*02:01, A*31, B*27, B*51:01, C*02; A*24:02, A*26, B*07, B*51:01, C*07
Country Japan
Experimental methods Chromium-release assay
Keywords epitope processing, escape

Notes

References

Yokomaku2004 Yoshiyuki Yokomaku, Hideka Miura, Hiroko Tomiyama, Ai Kawana-Tachikawa, Masafumi Takiguchi, Asato Kojima, Yoshiyuki Nagai, Aikichi Iwamoto, Zene Matsuda, and Koya Ariyoshi. Impaired Processing and Presentation of Cytotoxic-T-Lymphocyte (CTL) Epitopes Are Major Escape Mechanisms from CTL Immune Pressure in Human Immunodeficiency Virus Type 1 Infection. J. Virol., 78(3):1324-1332, Feb 2004. PubMed ID: 14722287. Show all entries for this paper.


Displaying record number 1458

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location p24(191-205)
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Ferrari2000 G. Ferrari, D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. AIDS Res. Hum. Retroviruses, 16(14):1433-43, 20 Sep 2000. PubMed ID: 11018863. Show all entries for this paper.


Displaying record number 58938

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HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location Gag
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Subtype A
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Kenya, Pakistan
Experimental methods Other
Keywords epitope processing

Notes

References

Abidi2013 Syed H. Abidi, Aniqa Shahid, Laila S. Lakhani, Muhammad R. Khanani, Peter Ojwang, Nancy Okinda, Reena Shah, Farhat Abbas, Sarah Rowland-Jones, and Syed Ali. Population-Specific Evolution of HIV Gag Epitopes in Genetically Diverged Patients. Infect. Genet. Evol., 16:78-86, Jun 2013. PubMed ID: 23403357. Show all entries for this paper.


Displaying record number 59422

Download this epitope record as JSON.

HXB2 Location Gag(325-333)
p24(193-201)
DNA(1762..1788)
Gag Epitope Map
Author Location Gag
Epitope NANPDCKTI Epitope Alignment
NANPDCKTI epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA LTNP/EC-17: A*11, A*24, B*35, B*38, C*04, C*12
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, immunodominance

Notes

References

Migueles2015 Stephen A. Migueles, Daniel Mendoza, Matthew G. Zimmerman, Kelly M. Martins, Sushila A. Toulmin, Elizabeth P. Kelly, Bennett A. Peterson, Sarah A. Johnson, Eric Galson, Kate O. Poropatich, Andy Patamawenu, Hiromi Imamichi, Alexander Ober, Catherine A. Rehm, Sara Jones, Claire W. Hallahan, Dean A. Follmann, and Mark Connors. CD8+ T-Cell Cytotoxic Capacity Associated with Human Immunodeficiency Virus-1 Control Can Be Mediated through Various Epitopes and Human Leukocyte Antigen Types. EBioMedicine, 2(1):46-58, Jan 2015. PubMed ID: 26137533. Show all entries for this paper.


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