HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 1397

Download this epitope record as JSON.

HXB2 Location Nef(79-87)
DNA(9031..9057)
Nef Epitope Map
Author Location Nef(81-89 HXB3)
Epitope MTYKAALDL Epitope Alignment
MTYKAALDL epitope logo
Species (MHC/HLA) mouse(A*02:01)
Immunogen vaccine
Experimental methods  
Keywords binding affinity, computational epitope prediction

Vaccine Details

Vaccine type DNA, peptide
Vaccine strain B clade HXB3
Vaccine component Nef
Adjuvant Complete Freund's Adjuvant (CFA)

Notes

References

Sandberg2000 J. K. Sandberg, A. C. Leandersson, C. Devito, B. Kohleisen, V. Erfle, A. Achour, M. Levi, S. Schwartz, K. Karre, B. Wahren, and J. Hinkula. Human immunodeficiency virus type 1 Nef epitopes recognized in HLA-A2 transgenic mice in response to DNA and peptide immunization. Virology, 273(1):112-9, 20 Jul 2000. PubMed ID: 10891413. Show all entries for this paper.


Displaying record number 53176

Download this epitope record as JSON.

HXB2 Location Nef(79-87)
DNA(9031..9057)
Nef Epitope Map
Author Location Nef(79-87)
Epitope MTYKAALDL Epitope Alignment
MTYKAALDL epitope logo
Epitope Name Nef79-87
Species (MHC/HLA) human, humanized mouse(A2)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords responses in children, immunodominance, characterizing CD8+ T cells

Notes

References

Chandwani2004 R. Chandwani, K. A. Jordan, B. L. Shacklett, E. Papasavvas, L. J. Montaner, M. G. Rosenberg, D. F. Nixon, and J. K. Sandberg. Limited Magnitude and Breadth in the HLA-A2-Restricted CD8 T-Cell Response to Nef in Children with Vertically Acquired HIV-1 Infection. Scand. J. Immunol., 59(1):109-114, Jan 2004. PubMed ID: 14723629. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health