HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 5 matching records:

Displaying record number 61144

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HXB2 Location Gag(198-205)
p24(66-73)
DNA(1381..1404)
Gag Epitope Map
Author Location  
Epitope MQMLKETI Epitope Alignment
MQMLKETI epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human, mouse(B*52:01)
Immunogen HIV-1 infection, vaccine
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords vaccine-induced immune responses, vaccine antigen design

Vaccine Details

Vaccine type DNA, modified vaccinia Ankara (MVA), adenovirus
Vaccine strain B clade

Notes

References

Ondondo2016 Beatrice Ondondo, Hayato Murakoshi, Genevieve Clutton, Sultan Abdul-Jawad, Edmund G.-T. Wee, Hiroyuki Gatanaga, Shinichi Oka, Andrew J. McMichael, Masafumi Takiguchi, Bette Korber, and Tomáš Hanke. Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection. Mol. Ther., 24(4):832-842, Apr 2016. PubMed ID: 26743582. Show all entries for this paper.


Displaying record number 61494

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HXB2 Location Gag(198-205)
p24(66-73)
DNA(1381..1404)
Gag Epitope Map
Author Location HIV-1
Epitope MQMLKETI Epitope Alignment
MQMLKETI epitope logo
Epitope Name MI8
Subtype B
Species (MHC/HLA) human(B*52:01)
Immunogen HIV-1 infection
Patient MHC/HLA KI-774: B*52:01
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords optimal epitope, chronic infection

Notes

References

Chikata2017 Takayuki Chikata, Hayato Murakoshi, Madoka Koyanagi, Kazutaka Honda, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype. J. Infect. Dis., 216(11):1415-1424, 12 Dec 2017. PubMed ID: 28968792. Show all entries for this paper.


Displaying record number 61503

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HXB2 Location Gag(198-205)
p24(66-73)
DNA(1381..1404)
Gag Epitope Map
Author Location Gag(198-205)
Epitope MQMLKETI Epitope Alignment
MQMLKETI epitope logo
Epitope Name GagMI8
Subtype B
Species (MHC/HLA) human(B*52:01)
Immunogen HIV-1 infection
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords optimal epitope, novel epitope, chronic infection

Notes

References

Murakoshi2015 Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Naoki Ishizuka, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes. J. Virol., 89(10):5330-5339, May 2015. PubMed ID: 25741000. Show all entries for this paper.


Displaying record number 61504

Download this epitope record as JSON.

HXB2 Location Gag(198-205)
p24(66-73)
DNA(1381..1404)
Gag Epitope Map
Author Location Gag(199-209)
Epitope MQMLKETI Epitope Alignment
MQMLKETI epitope logo
Epitope Name GagQA11
Subtype B
Species (MHC/HLA) human(B*52:01)
Immunogen HIV-1 infection
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords optimal epitope, chronic infection

Notes

References

Murakoshi2015 Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Naoki Ishizuka, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes. J. Virol., 89(10):5330-5339, May 2015. PubMed ID: 25741000. Show all entries for this paper.


Displaying record number 61878

Download this epitope record as JSON.

HXB2 Location Gag(198-205)
p24(66-73)
DNA(1381..1404)
Gag Epitope Map
Author Location  
Epitope MQMLKETI Epitope Alignment
MQMLKETI epitope logo
Show epitope variants
Epitope Name Gag MI8
Subtype B
Species (MHC/HLA) human(B*52:01)
Immunogen HIV-1 infection, vaccine
Patient MHC/HLA KI-774: B*52:01; KI-108: A*24:02, B*52:01, C*12:02
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords vaccine-induced immune responses, viral replication

Notes

References

Murakoshi2019 Hayato Murakoshi, Nozomi Kuse, Tomohiro Akahoshi, Yu Zhang, Takayuki Chikata, Mohamed Ali Borghan, Hiroyuki Gatanaga, Shinichi Oka, Keiko Sakai, and Masafumi Takiguchi. Broad Recognition of Circulating HIV-1 by HIV-1-Specific Cytotoxic T-Lymphocytes with Strong Ability to Suppress HIV-1 Replication. J. Virol., 93(1), 1 Jan 2019. PubMed ID: 30333175. Show all entries for this paper.


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