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Search CTL/CD8+ T-Cell Epitope Database

Found 9 matching records:

Displaying record number 60018

HXB2 Location Gag(78-85)
p17(78-85)
DNA(1021..1044)
Gag Epitope Map
Author Location Gag(78-85)
Epitope LYNTVATL Epitope Alignment
LYNTVATL epitope logo
Epitope Name LL8
Species (MHC/HLA) human(A*02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 53691

HXB2 Location Gag(78-85)
p17(78-85)
DNA(1021..1044)
Gag Epitope Map
Author Location p17
Epitope LYNTVATL Epitope Alignment
LYNTVATL epitope logo
Subtype D
Species (MHC/HLA) human(A24)
Immunogen HIV-1 infection
Patient MHC/HLA A23, A24, B35, B58, Cw4, Cw7
Country Democratic Republic of the Congo
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction

Notes

References

Geels2005 Mark J. Geels, Sheri A. Dubey, Kiersten Anderson, Elly Baan, Margreet Bakker, Georgios Pollakis, William A. Paxton, John W. Shiver, and Jaap Goudsmit. Broad Cross-Clade T-Cell Responses to Gag in Individuals Infected with Human Immunodeficiency Virus Type 1 Non-B Clades (A to G): Importance of HLA Anchor Residue Conservation. J. Virol., 79(17):11247-11258, Sep 2005. PubMed ID: 16103177. Show all entries for this paper.


Displaying record number 60017

HXB2 Location Gag(78-85)
p17(78-85)
DNA(1021..1044)
Gag Epitope Map
Author Location Gag(78-85)
Epitope LYNTVATL Epitope Alignment
LYNTVATL epitope logo
Epitope Name LL8
Species (MHC/HLA) human(C*14)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 56363

HXB2 Location Gag(78-85)
p17(78-85)
DNA(1021..1044)
Gag Epitope Map
Author Location p17(78-85)
Epitope LYNTVATL Epitope Alignment
LYNTVATL epitope logo
Epitope Name LL8
Subtype B
Species (MHC/HLA) human(Cw*14)
Immunogen HIV-1 infection
Country Australia, Canada, Germany, United States
Experimental methods  
Keywords HLA associated polymorphism

Notes

References

Brumme2008 Zabrina L. Brumme, Chanson J. Brumme, Jonathan Carlson, Hendrik Streeck, Mina John, Quentin Eichbaum, Brian L Block, Brett Baker, Carl Kadie, Martin Markowitz, Heiko Jessen, Anthony D. Kelleher, Eric Rosenberg, John Kaldor, Yuko Yuki, Mary Carrington, Todd M. Allen, Simon Mallal, Marcus Altfeld, David Heckerman, and Bruce D. Walker. Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection. J. Virol., 82(18):9216-9227, Sep 2008. PubMed ID: 18614631. Show all entries for this paper.


Displaying record number 54143

HXB2 Location Gag(78-85)
p17(78-85)
DNA(1021..1044)
Gag Epitope Map
Author Location  
Epitope LYNTVATL Epitope Alignment
LYNTVATL epitope logo
Species (MHC/HLA) human(Cw*14)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 54942

HXB2 Location Gag(78-85)
p17(78-85)
DNA(1021..1044)
Gag Epitope Map
Author Location  
Epitope LYNTVATL Epitope Alignment
LYNTVATL epitope logo
Species (MHC/HLA) human(Cw*14)
Immunogen HIV-1 infection, vaccine
Patient MHC/HLA A*0201, A*1101; B*4002, B*5101
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Tetramer binding
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type canarypox
Vaccine strain B clade LAI, B clade MN
Vaccine component Gag-Pol, gp120, gp41

Notes

References

Horton2006a Helen Horton, Colin Havenar-Daughton, Deborah Lee, Erin Moore, Jianhong Cao, John McNevin, Thomas Andrus, Haiying Zhu, Abbe Rubin, Tuofu Zhu, Connie Celum, and M. Juliana McElrath. Induction of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses in HIV Vaccine Trial Participants Who Subsequently Acquire HIV-1 Infection. J. Virol., 80(19):9779-9788, Oct 2006. PubMed ID: 16973582. Show all entries for this paper.


Displaying record number 58974

HXB2 Location Gag(78-85)
p17(78-85)
DNA(1021..1044)
Gag Epitope Map
Author Location Gag(78-85)
Epitope LYNTVATL Epitope Alignment
LYNTVATL epitope logo
Subtype B
Species (MHC/HLA) human(Cw*1402)
Immunogen HIV-1 infection
Country Australia, Canada, Spain, Switzerland
Experimental methods Other
Keywords mutation acquisition

Notes

References

Bartha2013 István Bartha, Jonathan M. Carlson, Chanson J. Brumme, Paul J. McLaren, Zabrina L. Brumme, Mina John, David W. Haas, Javier Martinez-Picado, Judith Dalmau, Cecilio López-Galíndez, Concepción Casado, Andri Rauch, Huldrych F. Günthard, Enos Bernasconi, Pietro Vernazza, Thomas Klimkait, Sabine Yerly, Stephen J. O'Brien, Jennifer Listgarten, Nico Pfeifer, Christoph Lippert, Nicolo Fusi, Zoltán Kutalik, Todd M. Allen, Viktor Müller, P. Richard Harrigan, David Heckerman, Amalio Telenti, and Jacques Fellay. A Genome-to-Genome Analysis of Associations between Human Genetic Variation, HIV-1 Sequence Diversity, and Viral Control. eLife, 2:e01123, 2013. PubMed ID: 24171102. Show all entries for this paper.


Displaying record number 61909

HXB2 Location Gag(78-85)
p17(78-85)
DNA(1021..1044)
Gag Epitope Map
Author Location Gag
Epitope LYNTVATL Epitope Alignment
LYNTVATL epitope logo
Epitope Name Gag LL8
Species (MHC/HLA) human(Cw*1402, Cw*1403)
Immunogen HIV-1 infection
Experimental methods CTL suppression of replication, HLA binding, Other
Keywords NK cells

Notes

References

Lin2016 Zhansong Lin, Kimiko Kuroki, Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Ying Qi, Takayuki Chikata, Takuya Naruto, Madoka Koyanagi, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka, Mary Carrington, Katsumi Maenaka, and Masafumi Takiguchi. HIV-1 Control by NK Cells via Reduced Interaction between KIR2DL2 and HLA-C*12:02/C*14:03. Cell Rep., 17(9):2210-2220, 22 Nov 2016. PubMed ID: 27880898. Show all entries for this paper.


Displaying record number 55692

HXB2 Location Gag(78-85)
p17(78-85)
DNA(1021..1044)
Gag Epitope Map
Author Location Gag(78-85 SF2)
Epitope LYNTVATL Epitope Alignment
LYNTVATL epitope logo
Epitope Name LYN
Subtype B
Species (MHC/HLA) mouse(H-2d)
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type protein
Vaccine strain B clade SF2
Vaccine component Gag, Tat
Adjuvant Complete Freund's Adjuvant (CFA), Incomplete Freund's Adjuvant (IFA)

Notes

References

Cellini2008 Silvia Cellini, Cinzia Fortini, Eleonora Gallerani, Federica Destro, Egidio Brocca Cofano, Antonella Caputo, and Riccardo Gavioli. Identification of New HIV-1 Gag-Specific Cytotoxic T Lymphocyte Responses in BALB/c Mice. Virol. J., 5:81, 2008. PubMed ID: 18625037. Show all entries for this paper.


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