HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 10 matching records:

Displaying record number 55945

HXB2 Location Gag(34-44)
p17(34-44)
DNA(889..921)
Gag Epitope Map
Author Location p17
Epitope LVWASRELERF Epitope Alignment
LVWASRELERF epitope logo
Epitope Name LF11(p17)
Subtype B
Species (MHC/HLA) human(A30)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 60015

HXB2 Location Gag(34-44)
p17(34-44)
DNA(889..921)
Gag Epitope Map
Author Location Gag(34-44)
Epitope LVWASRELERF Epitope Alignment
LVWASRELERF epitope logo
Epitope Name LF11
Species (MHC/HLA) human(A*30)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 54118

HXB2 Location Gag(34-44)
p17(34-44)
DNA(889..921)
Gag Epitope Map
Author Location p17(34-44)
Epitope LVWASRELERF Epitope Alignment
LVWASRELERF epitope logo
Species (MHC/HLA) human(A*30)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 53056

HXB2 Location Gag(34-44)
p17(34-44)
DNA(889..921)
Gag Epitope Map
Author Location p17
Epitope LVWASRELERF Epitope Alignment
LVWASRELERF epitope logo
Epitope Name LF-11
Subtype C
Species (MHC/HLA) human(A*3002, B*5703)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD4 T-cell Elispot - IFNγ, CD8 T-cell Elispot - IFNγ, Chromium-release assay, Intracellular cytokine staining
Keywords subtype comparisons, epitope processing, immunodominance, HLA cross-presentation

Notes

References

Masemola2004a Agatha M. Masemola, Tumelo N. Mashishi, Greg Khoury, Helba Bredell, Maria Paximadis, Tiyani Mathebula, Debra Barkhan, Adrian Puren, Efthyia Vardas, Mark Colvin, Lynn Zijenah, David Katzenstein, Rosemary Musonda, Susan Allen, Newton Kumwenda, Taha Taha, Glenda Gray, James McIntyre, Salim Abdool Karim, Haynes W. Sheppard, and Clive M. Gray. Novel and Promiscuous CTL Epitopes in Conserved Regions of Gag Targeted by Individuals with Early Subtype C HIV Type 1 Infection from Southern Africa. J. Immunol., 173(7):4607-4617, 1 Oct 2004. PubMed ID: 15383595. Show all entries for this paper.


Displaying record number 60016

HXB2 Location Gag(34-44)
p17(34-44)
DNA(889..921)
Gag Epitope Map
Author Location Gag(34-44)
Epitope LVWASRELERF Epitope Alignment
LVWASRELERF epitope logo
Epitope Name LF11
Species (MHC/HLA) human(B*52)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 53307

HXB2 Location Gag(34-44)
p17(34-44)
DNA(889..921)
Gag Epitope Map
Author Location ( C consensus)
Epitope LVWASRELERF Epitope Alignment
LVWASRELERF epitope logo
Subtype C
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords characterizing CD8+ T cells

Notes

References

Kiepiela2004 Photini Kiepiela, Alasdair J. Leslie, Isobella Honeyborne, Danni Ramduth, Christina Thobakgale, Senica Chetty, Prinisha Rathnavalu, Corey Moore, Katja J. Pfafferott, Louise Hilton, Peter Zimbwa, Sarah Moore, Todd Allen, Christian Brander, Marylyn M. Addo, Marcus Altfeld, Ian James, Simon Mallal, Michael Bunce, Linda D. Barber, James Szinger, Cheryl Day, Paul Klenerman, James Mullins, Bette Korber, Hoosen M. Coovadia, Bruce D. Walker, and Philip J. R. Goulder. Dominant Influence of HLA-B in Mediating the Potential Co-Evolution of HIV and HLA. Nature, 432(7018):769-775, 9 Dec 2004. LA-UR 04-5920. PubMed ID: 15592417. Show all entries for this paper.


Displaying record number 60013

HXB2 Location Gag(34-44)
p17(34-44)
DNA(889..921)
Gag Epitope Map
Author Location Gag(34-44)
Epitope LVWASRELERF Epitope Alignment
LVWASRELERF epitope logo
Epitope Name LF11
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 58693

HXB2 Location Gag(34-44)
p17(34-44)
DNA(889..921)
Gag Epitope Map
Author Location p17(81-89)
Epitope LVWASRELERF Epitope Alignment
LVWASRELERF epitope logo
Epitope Name LF11
Subtype C
Species (MHC/HLA) human(B*5703)
Immunogen HIV-1 infection
Country Botswana, South Africa, Zimbabwe
Experimental methods CD8 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining, Tetramer binding
Keywords optimal epitope, HLA associated polymorphism, novel epitope

Notes

References

Kloverpris2012 Henrik N. Kloverpris, Anette Stryhn, Mikkel Harndahl, Mary van der Stok, Rebecca P. Payne, Philippa C. Matthews, Fabian Chen, Lynn Riddell, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HLA-B*57 Micropolymorphism Shapes HLA Allele-Specific Epitope Immunogenicity, Selection Pressure, and HIV Immune Control. J. Virol., 86(2):919-929, Jan 2012. PubMed ID: 22090105. Show all entries for this paper.


Displaying record number 53958

HXB2 Location Gag(34-44)
p17(34-44)
DNA(889..921)
Gag Epitope Map
Author Location ( C consensus)
Epitope LVWASRELERF Epitope Alignment
LVWASRELERF epitope logo
Subtype C
Species (MHC/HLA) human(B*5703)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 60014

HXB2 Location Gag(34-44)
p17(34-44)
DNA(889..921)
Gag Epitope Map
Author Location Gag(34-44)
Epitope LVWASRELERF Epitope Alignment
LVWASRELERF epitope logo
Epitope Name LF11
Species (MHC/HLA) human(C*04)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


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