HIV molecular immunology database
Found 11 matching records:
Download this epitope record as JSON.
HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | p17(34-44) | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Species (MHC/HLA) | human(A*30) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(34-44) | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Epitope Name | LF11 | |
Species (MHC/HLA) | human(A*30) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | p17 | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Epitope Name | LF11(p17) | |
Subtype | B | |
Species (MHC/HLA) | human(A30) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | chronic infection |
Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | p17 | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Epitope Name | LF-11 | |
Subtype | C | |
Species (MHC/HLA) | human(A*30:02, B*57:03) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD4 T-cell Elispot - IFNγ, CD8 T-cell Elispot - IFNγ, Chromium-release assay, Intracellular cytokine staining | |
Keywords | subtype comparisons, epitope processing, immunodominance, HLA cross-presentation |
Masemola2004a Agatha M. Masemola, Tumelo N. Mashishi, Greg Khoury, Helba Bredell, Maria Paximadis, Tiyani Mathebula, Debra Barkhan, Adrian Puren, Efthyia Vardas, Mark Colvin, Lynn Zijenah, David Katzenstein, Rosemary Musonda, Susan Allen, Newton Kumwenda, Taha Taha, Glenda Gray, James McIntyre, Salim Abdool Karim, Haynes W. Sheppard, and Clive M. Gray. Novel and Promiscuous CTL Epitopes in Conserved Regions of Gag Targeted by Individuals with Early Subtype C HIV Type 1 Infection from Southern Africa. J. Immunol., 173(7):4607-4617, 1 Oct 2004. PubMed ID: 15383595. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(34-44) | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Epitope Name | LF11 | |
Species (MHC/HLA) | human(B*52) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(34-44) | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Epitope Name | LF11 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | ( C consensus) | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(B57) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | characterizing CD8+ T cells |
Kiepiela2004 Photini Kiepiela, Alasdair J. Leslie, Isobella Honeyborne, Danni Ramduth, Christina Thobakgale, Senica Chetty, Prinisha Rathnavalu, Corey Moore, Katja J. Pfafferott, Louise Hilton, Peter Zimbwa, Sarah Moore, Todd Allen, Christian Brander, Marylyn M. Addo, Marcus Altfeld, Ian James, Simon Mallal, Michael Bunce, Linda D. Barber, James Szinger, Cheryl Day, Paul Klenerman, James Mullins, Bette Korber, Hoosen M. Coovadia, Bruce D. Walker, and Philip J. R. Goulder. Dominant Influence of HLA-B in Mediating the Potential Co-Evolution of HIV and HLA. Nature, 432(7018):769-775, 9 Dec 2004. LA-UR 04-5920. PubMed ID: 15592417. Show all entries for this paper.
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HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | p17(81-89) | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Epitope Name | LF11 | |
Subtype | C | |
Species (MHC/HLA) | human(B*57:03) | |
Immunogen | HIV-1 infection | |
Country | Botswana, South Africa, Zimbabwe | |
Experimental methods | CD8 T-cell Elispot - IFNγ, HLA binding, Intracellular cytokine staining, Tetramer binding | |
Keywords | optimal epitope, HLA associated polymorphism, novel epitope |
Kloverpris2012 Henrik N. Kloverpris, Anette Stryhn, Mikkel Harndahl, Mary van der Stok, Rebecca P. Payne, Philippa C. Matthews, Fabian Chen, Lynn Riddell, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HLA-B*57 Micropolymorphism Shapes HLA Allele-Specific Epitope Immunogenicity, Selection Pressure, and HIV Immune Control. J. Virol., 86(2):919-929, Jan 2012. PubMed ID: 22090105. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | ( C consensus) | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human(B*57:03) | |
Immunogen | HIV-1 infection | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, optimal epitope |
Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(34-44) | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Epitope Name | LF11 | |
Species (MHC/HLA) | human(C*04) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(34-44) p17(34-44) DNA(889..921) |
Gag Epitope Map |
---|---|---|
Author Location | p17(34-44) | |
Epitope |
LVWASRELERF
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | assay or method development, protective allele |
Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.