HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 53989

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HXB2 Location Pol(132-141)
Protease(76-85)
DNA(2478..2507)
Pol Epitope Map
Author Location ( C consensus)
Epitope LVGPTPVNII Epitope Alignment
LVGPTPVNII epitope logo
Subtype C
Species (MHC/HLA) human(A*02:05)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, optimal epitope

Notes

References

Kiepiela2007 Photini Kiepiela, Kholiswa Ngumbela, Christina Thobakgale, Dhanwanthie Ramduth, Isobella Honeyborne, Eshia Moodley, Shabashini Reddy, Chantal de Pierres, Zenele Mncube, Nompumelelo Mkhwanazi, Karen Bishop, Mary van der Stok, Kriebashnie Nair, Nasreen Khan, Hayley Crawford, Rebecca Payne, Alasdair Leslie, Julia Prado, Andrew Prendergast, John Frater, Noel McCarthy, Christian Brander, Gerald H. Learn, David Nickle, Christine Rousseau, Hoosen Coovadia, James I. Mullins, David Heckerman, Bruce D. Walker, and Philip Goulder. CD8+ T-Cell Responses to Different HIV Proteins Have Discordant Associations with Viral Load. Nat. Med., 13(1):46-53, Jan 2007. PubMed ID: 17173051. Show all entries for this paper.


Displaying record number 57780

Download this epitope record as JSON.

HXB2 Location Pol(132-141)
Protease(76-85)
DNA(2478..2507)
Pol Epitope Map
Author Location ( H2d)
Epitope LVGPTPVNII Epitope Alignment
LVGPTPVNII epitope logo
Species (MHC/HLA) mouse, transgenic mouse
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ, CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, T-cell Elispot
Keywords vaccine-induced immune responses, variant cross-reactivity, drug resistance

Vaccine Details

Vaccine type DNA
Vaccine strain B clade LAI
Vaccine component Protease

Notes

References

Hallengard2011 David Hallengärd, B. Kristian Haller, Sarah Petersson, Andreas Boberg, Anna-Karin Maltais, Maria Isaguliants, Britta Wahren, and Andreas Bråve. Increased Expression and Immunogenicity of HIV-1 Protease Following Inactivation of the Enzymatic Activity. Vaccine, 29(4):839-348, 17 Jan 2011. PubMed ID: 21109032. Show all entries for this paper.


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