HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 11 matching records:

Displaying record number 60008

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location Pol(415-426)
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Epitope Name LY12
Species (MHC/HLA) human(A*30)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 56001

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location RT
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Epitope Name LY12(RT)
Subtype B
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 52988

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location Pol(260-271)
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Show epitope variants
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Patient MHC/HLA A3, A32, B15, B51, Cw03, Cw6, DQ7, DR4, DR8
Country Netherlands
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, escape

Notes

References

Geels2003 Mark J. Geels, Marion Cornelissen, Hanneke Schuitemaker, Kiersten Anderson, David Kwa, Jolanda Maas, John T. Dekker, Elly Baan, Fokla Zorgdrager, Remco van den Burg, Martijn van Beelen, Vladimir V. Lukashov, Tong-Ming Fu, William A. Paxton, Lia van der Hoek, Sheri A. Dubey, John W. Shiver, and Jaap Goudsmit. Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual. J. Virol., 77(23):12430-12440, Dec 2003. PubMed ID: 14610167. Show all entries for this paper.


Displaying record number 54351

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location RT
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Epitope Name B15-LY12(RT)
Species (MHC/HLA) human(B15)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 491

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location RT(415-426 IIIB)
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Species (MHC/HLA) human(B*1501)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

Notes

References

Llano2019 Anuska Llano, Samandhy CedeƱo, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 60007

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location Pol(415-426)
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Epitope Name LY12
Species (MHC/HLA) human(B*1501)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60010

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location Pol(415-426)
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Epitope Name LY12
Species (MHC/HLA) human(B*1503)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 60009

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location Pol(415-426)
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Epitope Name LY12
Species (MHC/HLA) human(B*27)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 1816

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location RT(260-271)
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Species (MHC/HLA) human(B*62)
Immunogen HIV-1 infection
Experimental methods  
Keywords immunodominance

Notes

References

Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.


Displaying record number 53753

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location Pol(415-426)
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Show epitope variants
Epitope Name LY12
Subtype B
Species (MHC/HLA) human(B62)
Immunogen HIV-1 infection
Patient MHC/HLA A*01, A*11, B*08, B*15, Cw*04, Cw*07
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Flow cytometric T-cell cytokine assay
Keywords escape, characterizing CD8+ T cells, optimal epitope

Notes

References

Koibuchi2005a Tomohiko Koibuchi, Todd M. Allen, Mathias Lichterfeld, Stanley K. Mui, Kristin M. O'Sullivan, Alicja Trocha, Spyros A. Kalams, R. Paul Johnson, and Bruce D. Walker. Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(13):8171-8181, Jul 2005. PubMed ID: 15956562. Show all entries for this paper.


Displaying record number 490

HXB2 Location Pol(415-426)
RT(260-271)
DNA(3327..3362)
Pol Epitope Map
Author Location RT(415-426 IIIB)
Epitope LVGKLNWASQIY Epitope Alignment
LVGKLNWASQIY epitope logo
Species (MHC/HLA) human(B62)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Brander1996 Christian Brander and Bruce Walker. The HLA-Class I Restricted CTL Response in HIV-1 Infection: Systematic Identification of Optimal Epitopes. In The HLA-Class I Restricted CTL Response in HIV-1 Infection: Systematic Identification of Optimal Epitopes. pages IV--50--IV--60. Los Alamos National Laboratory, Theoretical Biology and Biophysics, Los Alamos, New Mexico, 1996. URL: http://hiv-web.lanl.gov/immunology. Show all entries for this paper.

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.


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